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公开(公告)号:KR810001964B1
公开(公告)日:1981-12-01
申请号:KR770001712
申请日:1977-07-25
Applicant: HOECHST AG
Inventor: VERTESY L , SCHLINGMANN M
IPC: C12N1/08
Abstract: Process for reducing the lipid and nucleic acid content in microbial cell masses was described. Thus, dry cell masses of Methylomonas clarus was mixed with MeOH. While stirring, NH3 was added and dissolved. The mixt. was filtered and washed with MeOH. The cell mass was dried under vaccum and suspended in the water. The mixt. was held at 55≦̸C for 20 min., cooled, and centrifuged and the solids were mixed with water, stirred for 10 min. at 20≦̸C, and dried under reduced pressure to give title materials.
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公开(公告)号:US3767799A
公开(公告)日:1973-10-23
申请号:US3767799D
申请日:1971-07-16
Applicant: HOECHST AG
Inventor: SUKATSCH D , VERTESY L , PRAEVE P
CPC classification number: C12P1/06 , Y10S435/836
Abstract: AN ANTIBIOTIC, ACTIVE AGAINST GRAM-POSITIVE AND GRAMNEGATIVE BACTERIA AND MYCOBACTERIA, THE SODIUM SALT OF WHICH ANTIBIOTIC HAS THE FORMULA C31H44O7PNA, HAS AN ULTRA-VIOLET SPECTRUM SHOWING MAXIMA AT 284, 275.5, 264, AND 235 NANOMETERS, AND HAS AN INFRARED SPECTRUM SHOWING PEAKS AT 3400, 3080, 2920, 2820, 1725, 1640, 1445, 1370, 1160, 985, 890, AND 750 CM.-1. PROCESS FOR PREPARING SAID ANTIBIOTIC BY CULTIVATION OR BACILLUS LICHENIFORMIS VAR. MESENTERICUS.
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公开(公告)号:DK446481A
公开(公告)日:1982-04-10
申请号:DK446481
申请日:1981-10-08
Applicant: HOECHST AG
Inventor: VERTESY L , MRACEK M , BRAUNITZER G , ASCHAUER H
Abstract: What are disclosed are two peptides having alpha -amylase inactivator activity, a method for making the inhibitors, in combination, by culturing Streptomyces tendae 4158 or Streptomyces tendae HAG 1226, methods for separating the combination into its two components, and methods and compositions for treating diabetes, pre-diabetes, or adiposity by administration of such peptide alpha -amylase inhibitors.
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公开(公告)号:DK143414B
公开(公告)日:1981-08-17
申请号:DK159678
申请日:1978-04-11
Applicant: HOECHST AG
Inventor: OEDING V , PFAFF W , VERTESY L , WEIDENMUELLER H L
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公开(公告)号:SE7804095L
公开(公告)日:1979-10-12
申请号:SE7804095
申请日:1978-04-11
Applicant: HOECHST AG
Inventor: OEDING V , PFAFF W , VERTESY L , WEIDENMULLER H-L
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公开(公告)号:YU60392A
公开(公告)日:1994-09-09
申请号:YU60392
申请日:1992-06-11
Applicant: HOECHST AG
Inventor: VERTESY L , BETZ J , FEHLHABER H W , LIMBERT M
IPC: A61K31/33 , A61K31/00 , A61K38/00 , A61K38/12 , A61K38/14 , A61P31/00 , A61P31/04 , C07D519/00 , C07K1/02 , C07K1/113 , C07K1/20 , C07K7/06 , C07K7/52 , C07K9/00 , C07K14/195 , C07K14/41 , C12N1/20 , C12P21/00 , C12P21/02 , C12R1/04
Abstract: NOVI GLIKOPEPTIDI I POSTUPAK ZA NJIHOVU PROIZVODNJU, novi glikopeptidi: des-metil-balhimycin, jedinjenje formule C65H71Cl2N9O24, des-metilleucil-balhimycin, jedinjenje formule C59H60Cl2N8O23, des-gluko-balhimycin, jedinjenje formule C60H63Cl2N9O19, ureido-balhimycin, jedinjenje formule C67H74Cl2N10O25, des-metil-des-gluko-balhimycin jedinjenje formule C59H61Cl2N9O19, i balhimycin V, jedinjenje formule C73H84Cl2N10O26, metil-balhimycin, jedinjenje formule C65H75Cl2N9O24, i balhimycin R, jedinjenje formule C72H83Cl2N9O28, imaju antibiotičko dejstvo. Takodje je opisan postupak za dobijanje novih glikopeptida kultivisanjem mikroorganizama soja Acitinomyces Y-86, 21022 u vodenoj hranljivoj podlozi, nakon čega se željene jedinjenja izoluju i prečišćavaju.
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公开(公告)号:NZ198570A
公开(公告)日:1985-01-31
申请号:NZ19857081
申请日:1981-10-07
Applicant: HOECHST AG
Inventor: VERTESY L , MRACEK M , BRAUNITZER G , ASCHAUER H
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