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公开(公告)号：KR20180054635A
公开(公告)日：2018-05-24
申请号：KR20187008127
申请日：2016-09-21
Applicant: HOFFMANN LA ROCHE
Inventor： MATTEI PATRIZIO , HERT JEROME , HUNZIKER DANIEL , RUDOLPH MARKUS , SCHMITZ PETRA , DI GIORGIO PATRICK
IPC: C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5517 , A61P27/02 , C07D471/04
CPC classification number: C07D471/04
Abstract: 본발명은신규한하기화학식 I의화합물, 상기화합물을포함하는조성물, 및상기화합물의사용방법을제공한다: [화학식 I]상기식에서, R, R, Y, W, m, n, p 및 q는본원에정의된바와같다.
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公开(公告)号：KR20180053408A
公开(公告)日：2018-05-21
申请号：KR20187011566
申请日：2016-09-20
Applicant: HOFFMANN LA ROCHE
Inventor： HERT JEROME , HUNZIKER DANIEL , MATTEI PATRIZIO , RUDOLPH MARKUS , SCHMITZ PETRA , ULLMER CHRISTOPH
IPC: C07D487/04 , A61K31/407 , A61P27/02
CPC classification number: C07D487/04
Abstract: 본발명은신규한하기화학식 I의화합물, 상기화합물을포함하는조성물, 및상기화합물의사용방법을제공한다: [화학식 I]상기식에서, R, R, R, Y, W, m, n, p 및 q는본원에정의된바와같다.
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公开(公告)号：KR20180054830A
公开(公告)日：2018-05-24
申请号：KR20187011565
申请日：2016-09-20
Applicant: HOFFMANN LA ROCHE
Inventor： DI GIORGIO PATRICK , HERT JEROME , HUNZIKER DANIEL , MATTEI PATRIZIO , RUDOLPH MARKUS , SCHMITZ PETRA
IPC: C07D487/04 , A61K31/407 , A61P27/02
CPC classification number: C07D487/04 , C07D519/00
Abstract: 본발명은신규한하기화학식 I의화합물, 상기화합물을포함하는조성물, 및상기화합물의사용방법을제공한다: [화학식 I]상기식에서, R, R, R, Y, W, m, n, p 및 q는본원에정의된바와같다.
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公开(公告)号：KR20180054634A
公开(公告)日：2018-05-24
申请号：KR20187008126
申请日：2016-09-21
Applicant: HOFFMANN LA ROCHE
Inventor： DI GIORGIO PATRICK , HERT JEROME , HUNZIKER DANIEL , MATTEI PATRIZIO , RUDOLPH MARKUS , SCHMITZ PETRA , ULLMER CHRISTOPH
IPC: C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5517 , A61P27/02 , C07D471/04
CPC classification number: C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5517 , C07D471/04
Abstract: 본발명은신규한하기화학식 I의화합물, 상기화합물을포함하는조성물, 및상기화합물의사용방법을제공한다: [화학식 I]상기식에서, R, R, Y, W, m, n, p 및 q는본원에정의된바와같다.
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公开(公告)号：KR20180043837A
公开(公告)日：2018-04-30
申请号：KR20187009433
申请日：2016-09-01
Applicant: HOFFMANN LA ROCHE
Inventor： HERT JEROME , HUNZIKER DANIEL , KUEHNE HOLGER , LUEBBERS THOMAS , MARTIN RAINER E , MATTEI PATRIZIO , NEIDHART WERNER , RICHTER HANS , RUDOLPH MARKUS , PINARD EMMANUEL
IPC: C07D249/12 , A61K31/4196 , A61K31/4245 , A61P27/02 , A61P27/06 , C07D403/12 , C07D413/12
CPC classification number: C07D403/12 , C07D231/12 , C07D231/56 , C07D237/14 , C07D249/12 , C07D401/12 , C07D407/04 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04 , C07F7/0812
Abstract: 본발명은하기화학식 (I)의신규화합물, 상기화합물을포함하는조성물, 및상기화합물의사용방법을제공한다:(I) 상기식에서, R, R, R, R및 W는본원명세서에정의된바와같다.
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Patent Agency Ranking
公开(公告)号：WO2017050791A8
公开(公告)日：2017-07-06
申请号：PCT/EP2016072347
申请日：2016-09-21
Applicant: F HOFFMANN-LA ROCHE AG , HOFFMANN-LA ROCHE INC
Inventor： DI GIORGIO PATRICK , HERT JÉRÔME , HUNZIKER DANIEL , MATTEI PATRIZIO , RUDOLPH MARKUS , SCHMITZ PETRA , ULLMER CHRISTOPH
IPC: C07D471/04 , A61K31/407 , A61K31/437 , A61K31/5517 , A61P1/00 , A61P25/00 , A61P29/00 , A61P37/00 , C07D487/04
CPC classification number: C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5517 , C07D471/04
Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2,Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
Abstract translation: 本发明提供具有通式（I）的新化合物，其中R 1，R 2，Y，W，m，n，p和q如本文所定义，包括所述化合物的组合物和使用所述化合物的方法。
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公开(公告)号：MX381728B
公开(公告)日：2025-03-13
申请号：MX2019010772
申请日：2019-09-10
Applicant: HOFFMANN LA ROCHE
Inventor： HUNZIKER DANIEL , GOMME JUSTIN , HERT JÉRÔME , RUDOLPH MARKUS , DI GIORGIO PATRICK , MATTEI PATRIZIO , SCHMITZ PETRA
IPC: A61K31/397 , A61K31/4025 , A61K31/496 , A61P27/02 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: La invención proporciona nuevos compuestos que tienen la fórmula general (I) (ver Fórmula) en la que R1, R2, Y, X, W, m y n son como se definen en el presente documento, composiciones que incluyen los compuestos y métodos de uso de los compuestos.
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公开(公告)号：PH12019502118A1
公开(公告)日：2020-07-06
申请号：PH12019502118
申请日：2019-09-16
Applicant: HOFFMANN LA ROCHE
Inventor： MATTEI PATRIZIO , HERT JRME , HUNZIKER DANIEL , RUDOLPH MARKUS , SCHMITZ PETRA , DI GIORGIO PATRICK , GOMME JUSTIN
IPC: A61K31/4025 , A61K31/397 , A61K31/496 , A61P27/02 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: The invention provides novel compounds having the general formula (I) wherein R1 is selected from substituted phenyl, pyridinyl or thiophenyl, R2 is selected from optionally substituted aminosulphonylphenyl, aminosulphonylpyridinyl, aminosulphonylthiophenyl or aminosulphonylthiazolyl, X is nitrogen or carbon, Y is a linking group, Z is a direct bond or a linking group, m = 0-5, n = 0-5 with the proviso that m+n is 2-5, compositions including the compounds and the use of the compounds in the treatment or prophylaxis of ocular conditions.
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公开(公告)号：MA49879A
公开(公告)日：2020-06-24
申请号：MA49879
申请日：2018-03-13
Applicant: HOFFMANN LA ROCHE
Inventor： DI GIORGIO PATRICK , GOMME JUSTIN , HERT JÉRÔME , HUNZIKER DANIEL , MATTEI PATRIZIO , RUDOLPH MARKUS , SCHMITZ PETRA
IPC: A61K31/397 , A61K31/4025 , A61K31/496 , A61P27/02 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D405/14 , C07D409/14 , C07D417/14
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公开(公告)号：HUE046820T2
公开(公告)日：2020-03-30
申请号：HUE15711203
申请日：2015-03-23
Applicant: HOFFMANN LA ROCHE
Inventor： DI GIORGIO PATRICK , HERT JERÔME , HUNZIKER DANIEL , KUEHNE HOLGER , MATTEI PATRIZIO , RUDOLPH MARKUS
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