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公开(公告)号：WO0210713A3
公开(公告)日：2003-12-24
申请号：PCT/US0124118
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , MARTA TERESA M , PADMANABHAN ARAVIND , STARTEN ERNEST ALLEN , CABUZ EUGEN LOAN , BONNE ULRICH , OHNSTEIN THOMAS RAYMOND , COX JAMES ALLEN , ZOOK DAVID J
IPC: G01N33/49 , B01L3/00 , G01N15/14 , G01N33/487 , G05D7/06
CPC classification number: G01N15/1404 , A61B5/150022 , A61B5/15003 , A61B5/150221 , A61B5/150343 , A61B5/150351 , A61B5/150809 , A61B5/150824 , A61B5/157 , B01L3/5027 , G01N2015/1486 , Y10T436/101666
Abstract: A portable or wearable cytometer (10) that can be used at remote locations, such as in the field or at home. The flow cytometer (10) of the present invention may help improve the healthcare of many weak, sick or elderly people by providing early detection of infection. By detecting the infection early, the infection may be more readily treatable. In military applications, the portable cytometer (10) of the present invention may help save lives by providing early detection of infection due to biological agents.
Abstract translation: 便携式或可穿戴式的血细胞计数器（10），其可以在远程位置使用，例如在野外或在家中使用。 本发明的流式细胞仪（10）可以通过提供早期检测感染来帮助改善许多弱者，病人或老年人的医疗保健。 通过早期检测感染，感染可能更容易治疗。 在军事应用中，本发明的便携式血细胞计数器（10）可以通过提供由于生物制剂引起的感染的早期检测来帮助挽救生命。
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公开(公告)号：WO0210714A2
公开(公告)日：2002-02-07
申请号：PCT/US0124119
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , MARTA TERESA , PADMANABHAN ARAVIND , COX JAMES ALLEN , ZOOK DAVID J
CPC classification number: G01N15/1456 , G01N15/1434 , G01N35/085 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0238 , G01N2015/1075
Abstract: An optical detection system for flow cytometry that uses two or more light sources (208,210) positioned laterally at different distances from the central axis (202) of the flow stream (50) for providing light through different parts of the flow stream (50). Byusing two or more light sources (208,210), the particle position can be detected, and the alignment and width of the core stream (160) can be monitored and controlled. In addition, the velocity and size of the particles can be more accurately determined than when only a single light source is used.
Abstract translation: 一种用于流式细胞术的光学检测系统，其使用两个或更多个光源（208,210），所述两个或更多个光源（208,210）横向定位在与所述流动流（50）的中心轴线（202）不同的距离处，用于通过所述流动流（50）的不同部分提供光。 通过使用两个或更多个光源（208,210），可以检测颗粒位置，并且可以监测和控制核心流（160）的对准和宽度。 此外，与仅使用单个光源相比，可以更准确地确定颗粒的速度和尺寸。
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3.发明申请FREQUENCY-MULTIPLEXED DETECTION OF MULTIPLE WAVELENGTH LIGHT FOR FLOW CYTOMETRY 审中-公开用于流式细胞术的多波长光的频繁多重检测
公开(公告)号：WO2006026766A3
公开(公告)日：2006-06-01
申请号：PCT/US2005031493
申请日：2005-09-01
Applicant: HONEYWELL INT INC , COX JAMES A , ZOOK DAVID J
Inventor： COX JAMES A , ZOOK DAVID J
IPC: G01N15/14
CPC classification number: G01N15/1459 , G01N2015/1438 , G01N2015/1477 , G01N2015/1486 , G01N2201/0691
Abstract: A multiplexed set of light sources having outputs of light with various wavelengths which are combined into one beam. The beam may impinge a particle in a flow channel of a cytometer. The light leaving the flow channel may be sensed by a detector and the light distinguished according to wavelength.
Abstract translation: 具有不同波长的光输出组合成一个光束的多路复用光源组。 该束可以将粒子撞击在细胞计数器的流动通道中。 离开流动通道的光可以被检测器感测并且光根据波长来区分。
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公开(公告)号：WO0210874A3
公开(公告)日：2002-07-18
申请号：PCT/US0124120
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , SATREN ERNEST ALLEN , CABUZ EUGEN LOAN , BONNE ULRICH , OHNSTEIN THOMAS RAYMOND , ZOOK DAVID J
CPC classification number: G05D7/0694 , G01N15/1404 , Y10T137/0368 , Y10T137/0396 , Y10T137/7759 , Y10T137/7761 , Y10T137/87265
Abstract: A fluid driving system for portable flow cytometers (10) or other portable devices that accept a less precise and less stable pressure source, and then adjusts the pressure in a closed-loop manner to maintain a constant, desired flow velocity. The fluid driving system may be used in portable or wearable cytometers (10) for use in remote locations, such as at home or in the field.
Abstract translation: 用于便携式流式细胞仪（10）或其他便携式装置的流体驱动系统，其接受较不精确和较不稳定的压力源，然后以闭环方式调节压力以保持恒定的所需流速。 流体驱动系统可以用于便携式或可穿戴血细胞计数器（10），以用于远程位置，例如在家中或在田间。
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公开(公告)号：DE602005021253D1
公开(公告)日：2010-06-24
申请号：DE602005021253
申请日：2005-12-16
Applicant: HONEYWELL INT INC
Inventor： WANG TZU-YU , ZOOK DAVID J , SHIFFER STEPHEN R , CABUZ EUGEN I , CABUZ CLEOPATRA
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Patent Agency Ranking
公开(公告)号：AT354122T
公开(公告)日：2007-03-15
申请号：AT01961840
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , MARTA TERESA M , PADMANABHAN ARAVIND , STARTEN ERNEST ALLEN , CABUZ EUGEN LOAN , BONNE ULRICH , OHNSTEIN THOMAS RAYMOND , COX JAMES ALLEN , ZOOK DAVID J
IPC: G01N33/49 , B01L3/00 , G01N15/14 , G01N33/487 , G05D7/06
Abstract: A portable or wearable cytometer that can be used at remote locations, such as in the field or at home. The flow cytometer of the present invention may help improve the healthcare of many weak, sick or elderly people by providing early detection of infection. By detecting the infection early, the infection may be more readily treatable. In military applications, the portable cytometer of the present invention may help save lives by providing early detection of infection due to biological agents.
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公开(公告)号：DE60126680T2
公开(公告)日：2007-11-15
申请号：DE60126680
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , MARTA TERESA M , PADMANABHAN ARAVIND , STARTEN ERNEST ALLEN , CABUZ EUGEN LOAN , BONNE ULRICH , OHNSTEIN THOMAS RAYMOND , COX JAMES ALLEN , ZOOK DAVID J
IPC: G01N33/49 , G05D7/06 , B01L3/00 , G01N15/14 , G01N33/487
Abstract: A portable or wearable cytometer that can be used at remote locations, such as in the field or at home. The flow cytometer of the present invention may help improve the healthcare of many weak, sick or elderly people by providing early detection of infection. By detecting the infection early, the infection may be more readily treatable. In military applications, the portable cytometer of the present invention may help save lives by providing early detection of infection due to biological agents.
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公开(公告)号：AU8307501A
公开(公告)日：2002-02-13
申请号：AU8307501
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , SATREN ERNEST ALLEN , CABUZ EUGEN LOAN , BONNE ULRICH , OHNSTEIN THOMAS RAYMOND , ZOOK DAVID J
Abstract: A fluid driving system for portable flow cytometers or other portable devices that accepts a less precise and less stable pressure source, and then adjusts the pressure in a closed-loop manner to maintain a constant, desired flow velocity. The fluid driving system may be used in portable or wearable cytometers for use in remote locations, such as at home or in the field.
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公开(公告)号：AU8095601A
公开(公告)日：2002-02-13
申请号：AU8095601
申请日：2001-08-02
Applicant: HONEYWELL INT INC
Inventor： CABUZ CLEOPATRA , MARTA TERESA , PADMANABHAN ARAVIND , COX JAMES ALLEN , ZOOK DAVID J
Abstract: An optical detection system for flow cytometry that uses two or more light sources positioned laterally at different distances from the central axis of the flow stream for providing light through different parts of the flow stream. By using two or more light sources, the particle position can be detected, and the alignment and width of the core stream can be monitored and controlled. In addition, the velocity and size of the particles can be more accurately determined than when only a single light source is used.
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公开(公告)号：DE60323735D1
公开(公告)日：2008-11-06
申请号：DE60323735
申请日：2003-03-17
Applicant: HONEYWELL INT INC
Inventor： COLE BARRETT E , ZOOK DAVID J
IPC: G01J5/02
Abstract: The present invention relates to a sensor comprising: a thermally isolated area on a substrate; a heating element proximate the thermally isolated area; a pair of conductors each having a portion adjacent a portion of the other; and a plurality of carbon nanotubes formed extending from one of the conductors to the other.
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