公开(公告)号：GB2542063A

公开(公告)日：2017-03-08

申请号：GB201621585

申请日：2015-06-05

Applicant: IBM

Inventor： DYLAN JOSEPH BODAY ,  JEANNETTE M GARCIA ,  JAMES L HEDRICK ,  RUDY J WOJTECKI ,  GAVIN O JONES

IPC: C02F1/28 ,  B01D15/08 ,  B01J20/26 ,  C02F101/20

Abstract: Method for controlling metals in a liquid are described. The liquid is contacted with a hexahydrotriazine and/or a hemiaminal material, and metal is adsorbed from the liquid onto the material. The hexahydrotriazine and/or hemiaminal material may be made from a diamine and an aldehyde.

公开(公告)号：GB2543222B

公开(公告)日：2017-06-28

申请号：GB201701185

申请日：2015-09-01

Applicant: IBM ,  AGENCY FOR SCIENCE TECH AND RES (A*STAR)

Inventor： AMANDA CATHERINE ENGLER ,  DANIEL JOSEPH COADY ,  JAMES L HEDRICK ,  YI YAN YANG ,  XIYU KE

IPC: C08G64/02 ,  A61K47/34 ,  C08G64/42

Abstract: Water soluble biodegradable polymers were prepared by an organoacid catalyzed ring opening polymerization (ROP) of a cyclic carbonate monomer bearing an active ester side chain. The initial polymer comprising an active ester side chain was treated with an amino-alcohol, which transformed the active ester groups to N-substituted amide groups bearing mono-hydroxy alkyl groups and/or dihydroxy alkyl groups, thereby forming the water soluble polymers. The water-soluble polymers are non-toxic and exhibit stealth properties in buffered serum solution.

公开(公告)号：GB2543197A

公开(公告)日：2017-04-12

申请号：GB201621583

申请日：2015-06-05

Applicant: IBM

Inventor： DYLAN JOSEPH BODAY ,  JEANNETTE M GARCIA ,  JAMES L HEDRICK ,  RUDY J WOJTECKI ,  GAVIN O JONES

IPC: C02F1/28 ,  B01D15/08 ,  B01J20/26 ,  C02F101/20

Abstract: Method and apparatus for controlling metals in a liquid are described. The liquid is contacted with a hexahydrotriazine and/or a hemiaminal material, and metal is adsorbed from the liquid onto the material. The hexahydrotriazine and/or hemiaminal material may be made from a diamine and an aldehyde.

公开(公告)号：GB2519914B

公开(公告)日：2018-03-14

申请号：GB201504011

申请日：2013-09-04

Applicant: IBM ,  AGENCY SCIENCE TECH & RES

Inventor： JAMES L HEDRICK ,  SHRINIVAS VENKATARAMAN ,  YI YAN YANG

IPC: A61K31/785 ,  A01N37/44 ,  A01N39/02 ,  A61L2/16 ,  A61P31/04

Abstract: An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2): wherein a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, and each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G′ is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X− is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions.

公开(公告)号：SG10201600620SA

公开(公告)日：2016-10-28

申请号：SG10201600620S

申请日：2016-01-26

Applicant: AGENCY SCIENCE TECH & RES ,  IBM

Inventor： JAMES L HEDRICK ,  CHAN JULIAN M W ,  WOJTECKI RUDY J ,  YANG YI YAN ,  ASHLYNN LEE

公开(公告)号：GB2543197B

公开(公告)日：2019-09-11

申请号：GB201621583

申请日：2015-06-05

Applicant: IBM

Inventor： DYLAN JOSEPH BODAY ,  JEANNETTE M GARCIA ,  JAMES L HEDRICK ,  RUDY J WOJTECKI ,  GAVIN O JONES

IPC: C02F1/28 ,  B01D15/08 ,  B01J20/26 ,  C02F101/20

Abstract: Method and apparatus for controlling metals in a liquid are described. The liquid is contacted with a hexahydrotriazine and/or a hemiaminal material, and metal is adsorbed from the liquid onto the material. The hexahydrotriazine and/or hemiaminal material may be made from a diamine and an aldehyde.

公开(公告)号：GB2542063B

公开(公告)日：2019-09-11

申请号：GB201621585

申请日：2015-06-05

Applicant: IBM

Inventor： DYLAN JOSEPH BODAY ,  JEANNETTE M GARCIA ,  JAMES L HEDRICK ,  RUDY J WOJTECKI ,  GAVIN O JONES

IPC: C02F1/28 ,  B01D15/08 ,  B01J20/26 ,  C02F101/20

Abstract: Method and apparatus for controlling metals in a liquid are described. The liquid is contacted with a hexahydrotriazine and/or a hemiaminal material, and metal is adsorbed from the liquid onto the material. The hexahydrotriazine and/or hemiaminal material may be made from a diamine and an aldehyde.

公开(公告)号：GB2543222A

公开(公告)日：2017-04-12

申请号：GB201701185

申请日：2015-09-01

Applicant: IBM ,  AGENCY FOR SCIENCE TECH AND RES (A*STAR)

Inventor： AMANDA CATHERINE ENGLER ,  DANIEL JOSEPH COADY ,  JAMES L HEDRICK ,  YI YAN YANG ,  XIYU KE

IPC: C08G64/02 ,  A61K47/34 ,  C08G64/42

Abstract: Water soluble biodegradable polymers were prepared by an organoacid catalyzed ring opening polymerization (ROP) of a cyclic carbonate monomer bearing an active ester side chain. The initial polymer comprising an active ester side chain was treated with an amino-alcohol, which transformed the active ester groups to N-substituted amide groups bearing mono-hydroxy alkyl groups and/or dihydroxy alkyl groups, thereby forming the water soluble polymers. The water- soluble polymers are non-toxic and exhibit stealth properties in buffered serum solution.