公开(公告)号：GB2601680A

公开(公告)日：2022-06-08

申请号：GB202202615

申请日：2020-07-15

Applicant: IBM ,  AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR

Inventor： NATHANIEL PARK ,  JAMES HEDRICK ,  GAVIN JONES ,  VICTORIA PIUNOVA ,  YI YAN YANG ,  PANG KERN JEREMY TAN ,  CHUAN YANG ,  CHERYLETTE ANNE ALEXANDER

IPC: A61K31/765 ,  A61P31/00 ,  A61P35/00

Abstract: Techniques regarding guanidinium functionalized polylysine polymers that can have antimicrobial and/or anticancer activity are provided. For example, one or more embodiments described herein can comprise a chemical composition, which can comprise a polymer comprising a molecular backbone covalently bonded to a pendent guanidinium functional group, wherein the molecular backbone can comprise a polylysine structure.

公开(公告)号：GB2601680B

公开(公告)日：2023-02-22

申请号：GB202202615

申请日：2020-07-15

Applicant: IBM ,  AGENCY SCIENCE TECH & RES

Inventor： NATHANIEL PARK ,  JAMES HEDRICK ,  GAVIN JONES ,  VICTORIA PIUNOVA ,  YI YAN YANG ,  PANG KERN JEREMY TAN ,  CHUAN YANG ,  CHERYLETTE ANNE ALEXANDER

IPC: A61K31/765 ,  A61P31/00 ,  A61P35/00

Abstract: Techniques regarding enhancing antimicrobial activity of antirheumatic agents by combination therapy are provided. For example, one or more embodiments described herein can regard a chemical composition comprising a polycarbonate polymer functionalized with a guanidinium functional group. The chemical composition can also comprise an antirheumatic agent, and the polycarbonate polymer can enhance an antimicrobial activity of the antirheumatic agent.

公开(公告)号：GB2583041B

公开(公告)日：2021-06-09

申请号：GB202010000

申请日：2018-12-03

Applicant: IBM

Inventor： NATHANIEL PARK ,  JAMES HEDRICK ,  GAVIN JONES

IPC: C08F251/00 ,  C08G18/28 ,  C08G18/32 ,  C08G18/83 ,  C08G64/42 ,  C08J7/12

Abstract: Techniques regarding chemical compounds comprising perfluoroaryl groups that can facilitate post-synthesis functionalization are provided. For example, one or more embodiments described herein can comprise a chemical compound. The chemical compound can comprise a molecular backbone. The chemical compound can also comprise a pendent functional group bonded to the molecular backbone. The pendent functional group can comprise a perfluoroaryl group and a methylene group.

公开(公告)号：GB2583041A

公开(公告)日：2020-10-14

申请号：GB202010000

申请日：2018-12-03

Applicant: IBM

Inventor： NATHANIEL PARK ,  JAMES HEDRICK ,  GAVIN JONES

IPC: C08F251/00 ,  C08G18/28 ,  C08G18/32 ,  C08G18/83 ,  C08G64/42 ,  C08J7/12

Abstract: Techniques regarding chemical compounds comprising perfluoroaryl groups that can facilitate post-synthesis functionalization are provided. For example, one or more embodiments described herein can comprise a chemical compound. The chemical compound can comprise a molecular backbone. The chemical compound can also comprise a pendent functional group bonded to the molecular backbone. The pendent functional group can comprise a perfluoroaryl group and a methylene group.