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公开(公告)号:GB2601680A
公开(公告)日:2022-06-08
申请号:GB202202615
申请日:2020-07-15
Applicant: IBM , AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR
Inventor: NATHANIEL PARK , JAMES HEDRICK , GAVIN JONES , VICTORIA PIUNOVA , YI YAN YANG , PANG KERN JEREMY TAN , CHUAN YANG , CHERYLETTE ANNE ALEXANDER
IPC: A61K31/765 , A61P31/00 , A61P35/00
Abstract: Techniques regarding guanidinium functionalized polylysine polymers that can have antimicrobial and/or anticancer activity are provided. For example, one or more embodiments described herein can comprise a chemical composition, which can comprise a polymer comprising a molecular backbone covalently bonded to a pendent guanidinium functional group, wherein the molecular backbone can comprise a polylysine structure.
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公开(公告)号:GB2548029B
公开(公告)日:2018-01-10
申请号:GB201707021
申请日:2016-02-09
Applicant: IBM , SAN JOSE STATE UNIV RESEARCH FOUNDATION
Inventor: YOUNG-HYE NA , GERAUD JEAN-MICHEL DUBOIS , JOSEPH SLY (DECEASED) , VICTORIA PIUNOVA , ROBERT DENNIS MILLER , DANIEL STILLMAN
Abstract: A thin film composite (TFC) forward osmosis (FO) membrane includes a porous support with surfaces having thereon a hydrophilic self-assembled monolayer. An active layer on the support is sufficiently dense to remove an ionic species from a liquid.
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公开(公告)号:GB2583304B
公开(公告)日:2022-07-20
申请号:GB202010225
申请日:2018-12-04
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: JAMES HEDRICK , MAREVA FEVRE , NATHANIEL PARK , VICTORIA PIUNOVA , YI YAN YANG , PANG KERN JEREMY TAN , CHUAN YANG
Abstract: Techniques regarding polymers with antimicrobial functionality are provided. For example, one or more embodiments described herein can regard a polymer, which can comprise a repeating ionene unit. The repeating ionene unit can comprise a cation distributed along a degradable backbone. The degradable backbone can comprise a terephthalamide structure. Further, the repeating ionene unit can have antimicrobial functionality.
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公开(公告)号:GB2580240B
公开(公告)日:2020-12-16
申请号:GB202003173
申请日:2018-11-09
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: VICTORIA PIUNOVA , NOAH FREDERICK FINE NATHEL , JAMES HEDRICK , YI YAN YANG , WILLY CHIN , ZHI XIANG VOO
IPC: A61K47/50 , A01N33/12 , A01N43/90 , A01N47/06 , A01N59/00 , A01P1/00 , A61L2/23 , C08G64/00 , C08G64/42 , C09D5/14 , C09D169/00
Abstract: Techniques regarding star polymers with enhanced antimicrobial functionality are provided. For example, a polymer is provided that can comprise a core that can have a singlet oxygen generator and that can generate a singlet oxygen species upon irradiation with light. The polymer can also comprise a plurality of polycarbonate arms covalently bonded to the core. The plurality of polycarbonate arms can be degradable and can comprise a cation. Further, the plurality of polycarbonate arms can have antimicrobial functionality.
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公开(公告)号:GB2599837A
公开(公告)日:2022-04-13
申请号:GB202200053
申请日:2020-05-07
Applicant: IBM
Inventor: DMITRY ZUBAREV , VICTORIA PIUNOVA , NATHANIEL PARK , JAMES HEDRICK
IPC: G06N3/00
Abstract: Techniques regarding autonomously controlling one or more chemical reactors using generative machine learning models are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a model component that can build a generative machine learning model based on training data regarding a past chemical reactor operation. The generative machine learning model can generate a recommended chemical reactor control setting for experimental discovery of a polymer.
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公开(公告)号:GB2583426B
公开(公告)日:2022-07-27
申请号:GB202010334
申请日:2018-12-04
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: JAMES HEDRICK , MAREVA FEVRE , VICTORIA PIUNOVA , NATHANIEL PARK , PANG KERN JEREMY TAN , YI YAN YANG , MU SAN ZHANG
IPC: C08G73/00 , A01N33/12 , A01N37/30 , A01N43/50 , C07C233/61 , C07C233/78
Abstract: Techniques regarding ionene compositions with antimicrobial functionality are provided. For example, one or more embodiments can comprise a monomer, which can comprise a single ionene unit. The single ionene unit can comprise a cation distributed along a molecular backbone. Also, a hydrophobic functional group can be covalently bonded to the molecular backbone, and the single ionene unit can have antimicrobial functionality.
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公开(公告)号:GB2583304A
公开(公告)日:2020-10-21
申请号:GB202010225
申请日:2018-12-04
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: JAMES HEDRICK , MAREVA FEVRE , NATHANIEL PARK , VICTORIA PIUNOVA , YI YAN YANG , PANG KERN JEREMY TAN , CHUAN YANG
Abstract: Disclosed is a polymer comprising a repeating ionene unit. The repeating ionene unit can comprise a cation distributed along a degradable backbone. The degradable backbone can comprise a terephthalamide structure. Further the repeating ionene unit can have antimicrobial functionality.
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公开(公告)号:GB2548029A
公开(公告)日:2017-09-06
申请号:GB201707021
申请日:2016-02-09
Applicant: IBM , SAN JOSE STATE UNIV RES FOUND
Inventor: YOUNG-HYE NA , GERAUD JEAN-MICHEL DUBOIS , JOSEPH SLY (DECEASED) , VICTORIA PIUNOVA , ROBERT DENNIS MILLER , DANIEL STILLMAN
Abstract: A thin film composite (TFC) forward osmosis (FO) membrane includes a porous support with surfaces having thereon a hydrophilic self-assembled monolayer. An active layer on the support is sufficiently dense to remove an ionic species from a liquid.
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公开(公告)号:GB2601680B
公开(公告)日:2023-02-22
申请号:GB202202615
申请日:2020-07-15
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: NATHANIEL PARK , JAMES HEDRICK , GAVIN JONES , VICTORIA PIUNOVA , YI YAN YANG , PANG KERN JEREMY TAN , CHUAN YANG , CHERYLETTE ANNE ALEXANDER
IPC: A61K31/765 , A61P31/00 , A61P35/00
Abstract: Techniques regarding enhancing antimicrobial activity of antirheumatic agents by combination therapy are provided. For example, one or more embodiments described herein can regard a chemical composition comprising a polycarbonate polymer functionalized with a guanidinium functional group. The chemical composition can also comprise an antirheumatic agent, and the polycarbonate polymer can enhance an antimicrobial activity of the antirheumatic agent.
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公开(公告)号:GB2583426A
公开(公告)日:2020-10-28
申请号:GB202010334
申请日:2018-12-04
Applicant: IBM , AGENCY SCIENCE TECH & RES
Inventor: JAMES HEDRICK , MAREVA FEVRE , VICTORIA PIUNOVA , NATHANIEL PARK , PANG KERN JEREMY TAN , YI YAN YANG , MU SAN ZHANG
IPC: C08G73/00
Abstract: Techniques regarding ionene compositions with antimicrobial functionality are provided. For example, one or more embodiments can comprise a monomer, which can comprise a single ionene unit. The single ionene unit can comprise a cation distributed along a molecular backbone. Also, a hydrophobic functional group can be covalently bonded to the molecular backbone, and the single ionene unit can have antimicrobial functionality.
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