公开(公告)号：WO9804920A3

公开(公告)日：1998-06-04

申请号：PCT/US9712737

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： KUMAR AMIT ,  JANG LARRY SHELDON ,  LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  PLATSHON MARK CHARLES

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  B01L3/00 ,  B01L9/06 ,  G01N35/04

CPC classification number: G01N21/03 ,  G01N21/6428 ,  G01N33/54366 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  G01N2021/0346 ,  G01N2021/6482

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：CA2261747A1

公开(公告)日：1998-02-05

申请号：CA2261747

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  KUMAR AMIT ,  PLATSHON MARK CHARLES ,  JANG LARRY SHELDON

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  G01N1/00 ,  G01N21/01

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：CA2261747C

公开(公告)日：2005-07-12

申请号：CA2261747

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： PLATSHON MARK CHARLES ,  ROCCO RICHARD MICHELE ,  JANG LARRY SHELDON ,  KUMAR AMIT ,  LEUNG DANTON KAI-YU

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  G01N1/00 ,  G01N21/01

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：AT262181T

公开(公告)日：2004-04-15

申请号：AT97935039

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： KUMAR AMIT ,  JANG LARRY SHELDON ,  LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  PLATSHON MARK CHARLES

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  B01L9/06 ,  B01L3/00 ,  G01N35/04

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：AU732627B2

公开(公告)日：2001-04-26

申请号：AU3807097

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： KUMAR AMIT ,  JANG LARRY SHELDON ,  LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  PLATSHON MARK CHARLES

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  B01L9/06 ,  B01L3/00 ,  G01N35/04

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：NZ333841A

公开(公告)日：2000-08-25

申请号：NZ33384197

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： KUMAR AMIT ,  JANG LARRY SHELDON ,  LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  PLATSHON MARK CHARLES

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  G01N35/04 ,  B01L3/00 ,  B01L9/06

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.

公开(公告)号：AU3807097A

公开(公告)日：1998-02-20

申请号：AU3807097

申请日：1997-07-22

Applicant: IDEXX LAB INC

Inventor： KUMAR AMIT ,  JANG LARRY SHELDON ,  LEUNG DANTON KAI-YU ,  ROCCO RICHARD MICHELE ,  PLATSHON MARK CHARLES

IPC: G01N21/03 ,  G01N21/64 ,  G01N33/543 ,  G01N33/552 ,  G01N33/94 ,  G01N35/00 ,  B01L9/06 ,  B01L3/00 ,  G01N35/04

Abstract: A fluorescent immunoassay employing the interior surface of a capillary tube is provided. Devices to permit immunoassays using one or more capillary tubes, an apparatus for use with the devices, and a process for screening for analyte in a sample using the devices and apparatus are also provided. Samples suspected of containing analyte are added to a disposable self-contained sample tray containing one or more sample wells, mixed with a reagent, drawn into one or more spaced-apart capillary tubes held within a disposable cartridge connected to an analytical apparatus, reacted with a binding member on the surface of the capillary tube, washed to stop the reaction, and dried by the apparatus. The capillary tube is then exposed to a signal generation device to create a fluorescence signal that is detected using a signal detector. The apparatus determines the presence of the analyte and optionally determines the amount of analyte present in the sample, and presents the results to the operator.