公开(公告)号：US11369770B2

公开(公告)日：2022-06-28

申请号：US16335762

申请日：2017-09-22

Applicant: INSTITUTE FOR BASIC SCIENCE

Inventor： Hee-Sup Shin ,  Charles Francois Vincent Latchoumane ,  Jan Born

IPC: A61M21/00 ,  A61N1/36 ,  A61N5/06 ,  A61N7/00 ,  A61N2/00

Abstract: The present invention relates to a brain stimulating device and, particularly, relates to a brain stimulating device comprising: a brainwave measurement unit for outputting a brainwave signal; and a stimulation unit for applying spindle-like stimulation to a brain in accordance with the generation of slow oscillation included in the brainwave signal. The brain stimulating device according to the present invention can reinforce memory or reduce memory deterioration due to dementia. Also, the brain stimulating device according to the present invention can reinforce hippocampus-dependent memory. Further, a portable device according to the present invention can control and monitor the brain stimulating device. Moreover, a method for assessing the performance of the brain stimulating device according to the present invention can assess the performance of the brain stimulating device.

公开(公告)号：US20230364423A1

公开(公告)日：2023-11-16

申请号：US18027023

申请日：2021-09-30

Applicant: The Board of Trustees of Leland Stanford Junior University ,  Institute for Basic Science

Inventor： Jin Hyung Lee ,  Hee-Sup Shin

IPC: A61N1/36 ,  A61N1/05 ,  A61N5/06 ,  A61K31/46 ,  A61K31/407 ,  A61P25/00

CPC classification number: A61N1/36082 ,  A61N1/0534 ,  A61N5/0622 ,  A61K31/46 ,  A61K31/407 ,  A61P25/00

Abstract: The disclosure pertains to methods for modifying empathy in a subject, such as a human, by modulating type 2 theta oscillations in a brain region of the subject. The methods include increasing empathy in a subject, such as a human, by increasing type 2 theta oscillations in a brain region of the subject, thereby increasing empathy in the subject. The human subject may have a psychiatric or neurological condition that causes suboptimal empathy. Modulating type 2 theta oscillations in a brain region of a subject can be accomplished by optogenetic treatment, electric stimulation of a brain region, administration of a pharmaceutical drug, or a combination thereof. Also provided are systems for performing the methods disclosed herein.