公开(公告)号：WO2013148666A1

公开(公告)日：2013-10-03

申请号：PCT/US2013/033856

申请日：2013-03-26

Applicant: INNOVATIVE SCIENCE TOOLS, INC.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/35

CPC classification number: G01N21/255 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/18 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/8507 ,  G01N21/9508 ,  G01N2021/475 ,  G01N2021/4759 ,  G01N2201/0627 ,  G01N2201/0631 ,  G02B6/4298

Abstract: A device and method for identifying solid and powdered materials use near-infrared reflection spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared reflection spectroscopy is employed within either the 700 - 1100 nm or the 900 - 1700 nm wavelength range to identify solid or powdered materials and determine whether they match specific known materials. Uses include identifying solid and powdered materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or powdered sample that consists of a mixture of components. A primary application involving identification analysis verification of the identify and purity of powdered materials used for fabricating drug tablets and capsules for quality control purposes.

Abstract translation: 用于识别固体和粉末材料的装置和方法使用近红外反射光谱结合多变量校准方法来分析光谱数据。 在700 - 1100 nm或900 - 1700 nm波长范围内使用近红外反射光谱法，以确定固体或粉末材料，并确定它们是否与特定的已知材料相匹配。 用途包括以大约2至15秒的快速测量周期时间识别固体和粉末材料，并采用不需要样品制备的方法，以及定量分析来确定固体或粉末样品中一种或多种化学成分的浓度 它由组分的混合物组成。 涉及用于制造药物片剂和胶囊用于质量控制目的的粉末材料的鉴定和纯度的识别分析验证的主要应用。

公开(公告)号：WO2013148656A1

公开(公告)日：2013-10-03

申请号：PCT/US2013/033844

申请日：2013-03-26

Applicant: INNOVATIVE SCIENCE TOOLS, INC.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/35

CPC classification number: G01N21/359 ,  G01J3/0205 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/9508 ,  G01N2201/06153 ,  G01N2201/0627 ,  G01N2201/0631

Abstract: A device and method for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared transmission spectroscopy is employed within either the 700 - 1100 nm or the 900 - 1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.

Abstract translation: 用于识别固体和液体材料的装置和方法使用近红外透射光谱与多变量校准方法结合用于分析光谱数据。 在700 - 1100 nm或900 - 1700 nm波长范围内采用近红外透射光谱法来识别固体或液体材料，并确定它们是否与特定的已知材料相匹配。 用途包括以约2至15秒的快速测量周期时间识别固体（包括粉末）和液体材料，并采用不需要样品制备的方法以及定量分析来确定一种或多种化学成分的浓度 固体或液体样品，由组分的混合物组成。 这种分析的主要应用包括检测假药片，胶囊和液体药物。

公开(公告)号：EP2831565B1

公开(公告)日：2019-01-23

申请号：EP13768319.9

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G02B6/42 ,  G01N21/85 ,  G01N21/95 ,  G01J3/02 ,  G01N21/47 ,  G01J3/18

公开(公告)号：EP3527969A2

公开(公告)日：2019-08-21

申请号：EP19162638.1

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G02B6/42 ,  G01N21/85 ,  G01N21/95 ,  G01J3/02 ,  G01J3/10 ,  G01J3/42

Abstract: An optical analyzer system for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. The device includes an optical concentrator (310) to increase efficiency of light transmission from the light source (305) through a sample aperture (320) to a sample holder (130). Near-infrared transmission spectroscopy is employed within either the 700 - 1100 nm or the 900 - 1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.

公开(公告)号：EP3527969A3

公开(公告)日：2019-11-20

申请号：EP19162638.1

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G02B6/42 ,  G01N21/85 ,  G01N21/95 ,  G01J3/02 ,  G01J3/10 ,  G01J3/42

Abstract: An optical analyzer system for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. The device includes an optical concentrator (310) to increase efficiency of light transmission from the light source (305) through a sample aperture (320) to a sample holder (130). Near-infrared transmission spectroscopy is employed within either the 700 - 1100 nm or the 900 - 1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.

公开(公告)号：EP2831566B1

公开(公告)日：2019-05-01

申请号：EP13768596.2

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/3563 ,  G01N21/3577 ,  G01J3/10 ,  G01N21/359 ,  G01J3/02 ,  G01J3/42 ,  G01N21/95

公开(公告)号：EP2831566A1

公开(公告)日：2015-02-04

申请号：EP13768596.2

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/35

CPC classification number: G01N21/359 ,  G01J3/0205 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/9508 ,  G01N2201/06153 ,  G01N2201/0627 ,  G01N2201/0631

Abstract: A device and method for identifying solid and liquid materials use near-infrared transmission spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared transmission spectroscopy is employed within either the 700-1100 nm or the 900-1700 nm wavelength range to identify solid or liquid materials and determine whether they match specific known materials. Uses include identifying solid (including powdered) and liquid materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or liquid sample that consists of a mixture of components. A primary application of such analysis includes detection of counterfeit drug tablets, capsules and liquid medications.

公开(公告)号：EP2831565A1

公开(公告)日：2015-02-04

申请号：EP13768319.9

申请日：2013-03-26

Applicant: Innovative Science Tools, Inc.

Inventor： MICHEELS, Ronald H. ,  LEE, Don J.

IPC: G01N21/35

CPC classification number: G01N21/255 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/18 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/8507 ,  G01N21/9508 ,  G01N2021/475 ,  G01N2021/4759 ,  G01N2201/0627 ,  G01N2201/0631 ,  G02B6/4298

Abstract: A device and method for identifying solid and powdered materials use near-infrared reflection spectroscopy combined with multivariate calibration methods for analysis of the spectral data. Near-infrared reflection spectroscopy is employed within either the 700 - 1100 nm or the 900 - 1700 nm wavelength range to identify solid or powdered materials and determine whether they match specific known materials. Uses include identifying solid and powdered materials with a fast measurement cycle time of about 2 to 15 seconds and with a method that requires no sample preparation, as well as quantitative analysis to determine the concentration of one or more chemical components in a solid or powdered sample that consists of a mixture of components. A primary application involving identification analysis verification of the identify and purity of powdered materials used for fabricating drug tablets and capsules for quality control purposes.