公开(公告)号：WO2013188546A2

公开(公告)日：2013-12-19

申请号：PCT/US2013/045430

申请日：2013-06-12

Applicant: INVISTA Technologies S.à.r.l.

Inventor： PEARLMAN, Paul S. ,  CHEN, Changlin ,  BOTES, Adriana ,  CONRADIE, Alex Van Eck

IPC: C12P5/02 ,  C12N9/00 ,  C07C11/167 ,  C12N9/02

CPC classification number: C12N9/0004 ,  C12P5/026 ,  C12Y401/01033 ,  C12Y402/01127 ,  C12Y402/03027 ,  Y02E50/343

Abstract: This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.

Abstract translation: 该文献描述了通过在丁二烯合成底物中形成两个乙烯基来生产丁二烯的生化途径。 本文描述的这些途径依赖于酶，例如甲羟戊酸二磷酸脱羧酶，异戊二烯合酶和用于最终酶促步骤的脱水酶。

公开(公告)号：EP2861745A2

公开(公告)日：2015-04-22

申请号：EP13739305.4

申请日：2013-06-12

Applicant: Invista Technologies S.à.r.l.

Inventor： PEARLMAN, Paul S. ,  CHEN, Changlin ,  BOTES, Adriana ,  CONRADIE, Alex Van Eck

IPC: C12P5/02 ,  C12N9/00 ,  C07C11/167 ,  C12N9/02

CPC classification number: C12N9/0004 ,  C12P5/026 ,  C12Y401/01033 ,  C12Y402/01127 ,  C12Y402/03027 ,  Y02E50/343

Abstract: This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.

Abstract translation: 该文献描述了通过在丁二烯合成底物中形成两个乙烯基来生产丁二烯的生化途径。 本文描述的这些途径依赖于酶，例如甲羟戊酸二磷酸脱羧酶，异戊二烯合酶和用于最终酶促步骤的脱水酶。

公开(公告)号：EP2791347A2

公开(公告)日：2014-10-22

申请号：EP12809062.8

申请日：2012-12-14

Applicant: Invista Technologies S.à.r.l.

Inventor： BOTES, Adriana ,  CONRADIE, Alex van Eck

IPC: C12P7/18 ,  C12P7/44 ,  C12P17/10 ,  C12P13/00

CPC classification number: C12P7/44 ,  C12N15/52 ,  C12P7/18 ,  C12P13/001 ,  C12P13/005 ,  C12P17/10

Abstract: This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.

公开(公告)号：EP2785848A2

公开(公告)日：2014-10-08

申请号：EP12799032.3

申请日：2012-11-30

Applicant: INVISTA Technologies S.à.r.l.

Inventor： PEARLMAN, Paul S. ,  CHEN, Changlin ,  BOTES, Adriana ,  CONRADIE, Alex Van Eck

IPC: C12P5/02 ,  C12N9/00 ,  C07C11/167

CPC classification number: C12P5/026 ,  C12N9/0004 ,  C12N9/88 ,  C12N15/52 ,  C12Y401/01033 ,  C12Y402/03027 ,  Y02E50/343

Abstract: This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.

Abstract translation: 该文件描述了通过在丁二烯合成底物中形成两个乙烯基来生产丁二烯的生物化学途径。 本文所述的这些途径依赖酶如甲羟戊酸二磷酸脱羧酶，异戊二烯合酶和脱水酶用于最后的酶促步骤。