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    1.
    发明专利
    未知

    公开(公告)号：DE602006012040D1

    公开(公告)日：2010-03-18

    申请号：DE602006012040

    申请日：2006-10-12

    Applicant: JSR CORP

    Inventor： TAMORI KOUJI ,  FUKUTA TETSUO ,  MURATA MITSUHIRO ,  UENO MASARU ,  KATAYOSE SATOSHI ,  TAKAMOTO EIJI ,  KASAI KIYOSHI

    IPC: G01N33/543

    Abstract: The organic polymer particles comprise a carboxyl group and 2,3-dihydroxypropyl group, and the magnetic particles for diagnostics comprise fine magnetic material particles and a polymer part containing a hydrophilic polymer part and a crosslinked polymer part, a dry coating film obtained from a water dispersion thereof having a contact angle with water of 5° to 60°. The process for producing the carboxyl group-containing particles comprises a step of producing an ester bond by reacting a hydroxyl group in organic polymer particles having the hydroxyl group with a carboxylic anhydride. The organic polymer particles comprise a hydroxyl group originating from a 2,3-dihydroxypropyl group and a polyoxyethylene group.

    4.
    发明专利
    未知

    公开(公告)号：DE602006010956D1

    公开(公告)日：2010-01-21

    申请号：DE602006010956

    申请日：2006-10-12

    Applicant: JSR CORP

    Inventor： TAMORI KOUJI ,  FUKUTA TETSUO ,  MURATA MITSUHIRO ,  UENO MASARU ,  KATAYOSE SATOSHI ,  TAKAMOTO EIJI ,  KASAI KIYOSHI

    IPC: G01N33/53 ,  C08G63/00

    Abstract: The organic polymer particles comprise a carboxyl group and 2,3-dihydroxypropyl group, and the magnetic particles for diagnostics comprise fine magnetic material particles and a polymer part containing a hydrophilic polymer part and a crosslinked polymer part, a dry coating film obtained from a water dispersion thereof having a contact angle with water of 5° to 60°. The process for producing the carboxyl group-containing particles comprises a step of producing an ester bond by reacting a hydroxyl group in organic polymer particles having the hydroxyl group with a carboxylic anhydride. The organic polymer particles comprise a hydroxyl group originating from a 2,3-dihydroxypropyl group and a polyoxyethylene group.

    Hollow polymer particle for immunodiagnosis, its manufacturing method, and reagent for immunodiagnosis
    7.
    发明专利
    Hollow polymer particle for immunodiagnosis, its manufacturing method, and reagent for immunodiagnosis 审中-公开
    用于免疫缺陷病的中空聚合物颗粒，其制造方法和免疫测定试剂

    公开(公告)号：JP2008215816A

    公开(公告)日：2008-09-18

    申请号：JP2007049169

    申请日：2007-02-28

    Applicant: Jsr Corp ,  Jsr株式会社

    Inventor： HAN KAKUN ,  KASAI KIYOSHI

    IPC: G01N33/545 ,  C08F2/22 ,  C08F291/00 ,  G01N33/543

    Abstract: PROBLEM TO BE SOLVED: To provide a hollow polymer particle for immunodiagnosis having excellent preservation stability and handleability, its manufacturing method, and a reagent for immunodiagnosis.
    SOLUTION: As for the hollow polymer particle for immunodiagnosis, a biochemical substance is immobilized on the surface, and the hollow rate is 5-80%, and the average particle size is 0.03-5.0 μm.
    COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供具有优异的保存稳定性和可操作性的免疫诊断用中空聚合物颗粒，其制造方法和免疫诊断用试剂。 解决方案：对于用于免疫诊断的中空聚合物颗粒，将生化物质固定在表面上，中空率为5-80％，平均粒径为0.03-5.0μm。 版权所有（C）2008，JPO＆INPIT

    Polymer particle for immunodiagnostic drug
    8.
    发明专利
    Polymer particle for immunodiagnostic drug 审中-公开
    用于免疫抑制剂的聚合物颗粒

    公开(公告)号：JP2006266970A

    公开(公告)日：2006-10-05

    申请号：JP2005087719

    申请日：2005-03-25

    Applicant: Jsr Corp ,  Jsr株式会社

    Inventor： KASAI KIYOSHI ,  HAN KAKUN

    IPC: G01N33/545 ,  C08F212/36

    Abstract: PROBLEM TO BE SOLVED: To provide a particle having a specific surface area more than a smooth surface particle, by making a particle surface layer irregular, and capable of coupling a large amount of antibodies per unit area, and suitable for highly sensitive and wide range measurement in a latex flocculation reaction.
    SOLUTION: This particle for an immunodiagnostic drug is a particle polymerized with a polymerizable unsaturated compound having a content of divinyl benzene more than 30 wt.%, having 0.02-2μm of particle size, having 20% or less of particle size fluctuation coefficient, and having a specific surface area, found by a nitrogen adsorption method, of at least 1.3 times of that calculated from an average particle size.
    COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题：为了提供具有比平滑表面颗粒更大的比表面积的颗粒，通过使颗粒表面层不规则，并且能够连接每单位面积的大量抗体，并且适合于高度敏感 并在胶乳絮凝反应中进行了广泛的测量。 解决方案：用于免疫诊断药物的该颗粒是具有二乙烯基苯含量大于30重量％的可聚合不饱和化合物的颗粒，其具有0.02-2μm的粒径，具有20％或更小的粒度波动 系数，并且具有通过氮吸附法找到的比表面积为由平均粒径计算的至少1.3倍。 版权所有（C）2007，JPO＆INPIT

    Physiologically active substance carrier polymer particle
    9.
    发明专利
    Physiologically active substance carrier polymer particle 审中-公开

    公开(公告)号：JP2004061301A

    公开(公告)日：2004-02-26

    申请号：JP2002220110

    申请日：2002-07-29

    Applicant: Jsr Corp ,  Jsr株式会社

    Inventor： KASAI KIYOSHI ,  MASUKAWA TORU

    IPC: G01N33/545 ,  C08F212/14 ,  C08F220/28 ,  C08F290/06 ,  G01N33/543

    CPC classification number: G01N33/54346 ,  C08F290/062

    Abstract: PROBLEM TO BE SOLVED: To provide physiologically active substance carrier polymer particles for sensitizing a protein substance such as an antibody, an antigen, an enzyme or a hormone, or a nucleic acid substance such as DNA/RNA, or a physiologically active sugar chain compound (physiologically active substance), to the particle surface by a chemical bonding method.
    SOLUTION: This physiologically active substance carrier polymer particles are acquired by radical emulsion polymerization of following compounds: (1) a radical polymeric vinyl monomer having a carboxylic acid group, 0.1-20 wt.%; (2) a compound shown by a following general formula (1) and a radical polymeric vinyl monomer having a strong acid group or either of them, 0.05-20 wt.%, the general formula (1): CH2=C(R
    1 )CO(OCH2CH2)nOR
    2 (In the formula, R1 shows a hydrogen atom or a methyl group, and R2 shows a hydrogen atom, C1-C6 alkyl group, an alkoxy phenyl group, a phenyl group, an acryloyl group or a methacryloyl group, and n shows the number of 2-22.); and (3) a radical polymeric vinyl monomer copolymerizable with a monomer described in (1) or (2), 40-99.8 wt.%.
    COPYRIGHT: (C)2004,JPO

    AQUEOUS DISPERSION OF POLYORGANOSILOAXNE/ORGANIC POLYMER COMPOSITE PARTICLE AND ITS PRODUCTION METHOD
    10.
    发明专利
    AQUEOUS DISPERSION OF POLYORGANOSILOAXNE/ORGANIC POLYMER COMPOSITE PARTICLE AND ITS PRODUCTION METHOD 失效

    公开(公告)号：JP2002201243A

    公开(公告)日：2002-07-19

    申请号：JP2000402548

    申请日：2000-12-28

    Applicant: JSR CORP

    Inventor： KASAI KIYOSHI ,  SAKURAI FUJIO ,  TAMORI KOJI

    IPC: C08F291/16 ,  C09D4/06 ,  C09D183/04 ,  C09D201/00

    Abstract: PROBLEM TO BE SOLVED: To provide an aqueous dispersion of polyorganosiloxane/organic polymer composite particles which, when used for a coating material, is excellent in craze resistance in drying and excellent in adhesiveness and resistances to weather, water, and staining; and a production method of the same. SOLUTION: This aqueous dispersion is prepared by causing (A) 1 pt.wt. seed polymer particles having a wt. average mol.wt. of 500-30,000 to absorb (B) 1-50 pts.wt. at least one silane component selected from among organosilanes, hydrolyzates of the organosilanes, and condensates of the organosilanes and (C) 1-100 pts.wt. free-radically polymerizable monomer in an aqueous medium and subjecting the silane component (B) to hydrolysis and condensation conditions and the free-radically polymerizable monomer to free- radical polymerization conditions.

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