公开(公告)号：US10018627B2

公开(公告)日：2018-07-10

申请号：US14513660

申请日：2014-10-14

Applicant: Japan Science and Technology Agency

Inventor： Hiroyuki Noji ,  Lisa Yamauchi

IPC: G01N33/543

CPC classification number: G01N33/54313 ,  G01N33/54393

Abstract: A technique for efficiently sealing many substances, such as beads, nucleic acid, protein, virus, cells, and lipid membrane complex, into an array is provided.The present invention provides a method for sealing a substance, including: (i) a step of introducing a first solvent containing a substance on a substrate on which a plurality of receptacles capable of storing the substance are formed separated from each other by a side wall; and (ii) a step of introducing a second solvent having a greater specific gravity than that of the first solvent onto the first solvent, the step (ii) being carried out after the step (i).

公开(公告)号：US10451619B2

公开(公告)日：2019-10-22

申请号：US15321312

申请日：2015-07-01

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki Noji ,  Lisa Yamauchi

IPC: G01N33/543 ,  C12Q1/04 ,  C12Q1/68 ,  C12Q1/70 ,  G01N37/00 ,  G01N35/10 ,  G01N21/64 ,  G01N33/53

Abstract: As a technique for efficiently sealing many substances, such as beads, nucleic acid, protein, virus, cells, and lipid membrane complex, into an array, the present invention provides a method for sealing a substance, including: (i) a step of introducing a first solvent containing a substance on a substrate on which a plurality of receptacles capable of storing the substance are formed separated from each other by a side wall; and (ii) a step of introducing a second solvent having a greater specific gravity than that of the first solvent onto the first solvent, the step (ii) being carried out after the step (i).