公开(公告)号：US10517928B2

公开(公告)日：2019-12-31

申请号：US15503078

申请日：2015-08-06

Applicant: KAGOSHIMA UNIVERSITY

Inventor： Akio Ido ,  Hirohito Tsubouchi ,  Yuga Komaki

IPC: A61K38/18 ,  A61L31/16 ,  A61L31/04 ,  A61P1/04

Abstract: According to this invention, the following are provided: a pharmaceutical composition for treating and/or preventing esophageal stenosis, comprising an HGF protein as an active ingredient (wherein the HGF protein may be a polypeptide that is any one of the following: (a) a polypeptide comprising the amino acid sequence shown in SEQ ID NO: 2; (b) a polypeptide comprising an amino acid sequence shown in SEQ ID NO: 2 in which one to several amino acids are deleted, substituted, or added; or (c) a polypeptide comprising an amino acid sequence having at least 90% identity with the amino acid sequence shown in SEQ ID NO: 2; and a stent comprising the pharmaceutical composition.