公开(公告)号：JP2002179703A

公开(公告)日：2002-06-26

申请号：JP2000381592

申请日：2000-12-15

Applicant: KAO CORP

Inventor： SHIRAHATA NOBORU ,  MASUKAWA KATSUNORI ,  KUZUKAWA MICHIYA ,  ONO SHIGEYUKI

IPC: A23L2/52 ,  C08B37/04

Abstract: PROBLEM TO BE SOLVED: To provide a method for separating polysaccharides in which an acidic polysaccharide and a neutral polysaccharide are separated simply and in high recovery rate from a mixed aqueous solution containing an acidic polysaccharide and a neutral polysaccharide. SOLUTION: This method for separating polysaccharides comprises separating an acidic polysaccharide from a neutral polysaccharide by jointly using a process in which an acidic polysaccharide is fractionated by gelling with addition of an acid and a process in which an acidic polysaccharide is fractionated by gelling with addition of a bi-valent or higher valent metal salt both to a mixed aqueous solution of polysaccharides containing an acidic polysaccharide and a neutral polysaccharide.

公开(公告)号：JPH05246990A

公开(公告)日：1993-09-24

申请号：JP4863192

申请日：1992-03-05

Applicant: KAO CORP

Inventor： TAMURA TADASHI ,  KIYOMINE AKIRA ,  MORITA OSAMU ,  KUZUKAWA MICHIYA ,  OGAWA MASAHIKO ,  TAGAMI HIDETOSHI ,  YOSHIHARA TORU

IPC: A61K8/00 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  C07D213/61 ,  C07D213/64 ,  C07D213/73 ,  C09B67/44 ,  D06P3/08 ,  A61K7/13

Abstract: PURPOSE:To provide the subject compound useful as a coupling substance to be added to corneal fiber-dyeing compositions, and giving the composition capable of dyeing the corneal fibers such as hair into a blue color tone in a high chroma and excellent in the dyeability, discoloration resistance and washing resistance. CONSTITUTION:A compound of formula I (R , R are H, lower alkyl capable of being substituted with an OH group; Ar is substitutable aryl; m is 0-4; n is 1-4; l is 0, 1) or its salt, for example, 1,2-bis-(3,5-diamino-2-pyridyloxy)ethane.4 hydrochloride. The compound is obtained e.g. by reacting a 2-halogeno-3,5- dinitropyridine of formula II (X is halogen) with an aryl-substituted metal alkoxide of formula III (M is alkali metal; Ar' is Ar) in a solvent such as THF at a temperature of -5 deg.C to the boiling point of the solvent and subsequently reducing the product in the presence of a catalyst such as palladium carbon catalyst.

公开(公告)号：JP2000206067A

公开(公告)日：2000-07-28

申请号：JP225399

申请日：1999-01-07

Applicant: KAO CORP

Inventor： SHINOZAKI TAKAO ,  KUZUKAWA MICHIYA ,  MURATA KUNIHIRO ,  HOSOKAWA HITOSHI ,  SHIMIZU MOMOKO ,  SHIMA HIROSHI

IPC: A61K8/00 ,  A61B5/055 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/06 ,  G01N24/08 ,  G01R33/48 ,  A61K7/027

Abstract: PROBLEM TO BE SOLVED: To nondestructively and accurately evaluate and predict the degree of oil bleeding on the surface of a lipstick by obtaining a T2 emphasis image or a spin density image on the cross section of the lipstick by the NMR imaging method, and using the ratio between the maximum and minimum values of the signal strength. SOLUTION: A test tube is used to suppress the vibration of a sample. In this case, glass with a shape suited for the shape of the sample, a test tube made of resin, or a sample tube for NMR, especially a sample tube made of resin or rubber being formed to the shape of a lipstick or a lipstick container, are preferable. The lipstick sample is charged into an NMR imaging device, imaging measurement is made to obtain a T2 emphasis image or a spin density image, and the signal strength of the cross section of the lipstick is obtained from the image. In general, the spin echo method or the gradient echo method is utilized as a method for imaging the inside of the lipstick. The arithmetic averaging value of the strength of each pixel is obtained, where the pixel exists within a circle of a radius (x) mm (x indicates value of 1-10% of the radius of the lipstick) with a point where the signal strength is maximized and a point where the signal strength is minimized as a center.

公开(公告)号：JP2000206066A

公开(公告)日：2000-07-28

申请号：JP225299

申请日：1999-01-07

Applicant: KAO CORP

Inventor： SHINOZAKI TAKAO ,  KUZUKAWA MICHIYA ,  MURATA KUNIHIRO ,  HOSOKAWA HITOSHI ,  SHIMIZU MOMOKO ,  SHIMA HIROSHI

IPC: A61K8/00 ,  A61B5/055 ,  A61Q1/06 ,  A61Q11/00 ,  G01N24/08 ,  G01R33/48 ,  A61K7/027

Abstract: PROBLEM TO BE SOLVED: To accurately evaluate the easiness to break of a lipstick in a non- destructive manner. SOLUTION: The T2 emphasized image of the transverse section or vertical section of a lipstick is obtained by the NMR(nuclear magnetic resonance) imaging method and a ratio of the average value of signal intensities of the outer peripheral portion of the lipstick from the surface thereof to X% (X=5-70) of the radius thereof and the average value of signal intensities of the center portion of the lipstick from the center thereof to Y% of the radius thereof is used to evaluate the easiness to breakage of the lipstick in a non-destructive manner.

公开(公告)号：JPH0428770A

公开(公告)日：1992-01-31

申请号：JP13299090

申请日：1990-05-23

Applicant: KAO CORP

Inventor： KUZUKAWA MICHIYA ,  OKADA SHIGENOBU ,  KANBE REIKO ,  IKEDA YUZO ,  YOSHIMURA KOICHI

IPC: C09B31/068 ,  C09B67/54

Abstract: PURPOSE:To obtain Red No.225 without skin sensitization by recrystallizing the Red No.225 and removing a specific compound from the recrystallized substance using column chromatography. CONSTITUTION:Red No.225 is preferably recrystallized from a mixed solution of hexane and chloroform at (1:5) to (5:1) ratio. A compound expressed by the formula is then removed from the resultant recrystallized substance using carbon tetrachloride or a mixture solution of benzene and chloroform preferably as an eluent by column chromatography to remove a compound expressed by the formula and afford the objective coloring matter.

公开(公告)号：JPS6478135A

公开(公告)日：1989-03-23

申请号：JP23650087

申请日：1987-09-21

Applicant: KAO CORP

Inventor： TAKANO SATOSHI ,  KUZUKAWA MICHIYA

IPC: G01N21/79 ,  G01N31/00 ,  G01N31/16

Abstract: PURPOSE:To easily execute the measurement by split-phase titration of various kinds of ionic surfactants by using a specific split-phase indicator alone or previously preparing two kinds of dyes which are suitable for use under an alkaline condition and acidic condition and are approximately equal in the wavelength of absorption maximal as the split-phase indicator. CONSTITUTION:Direct titration or back titration is executed by using a heterogeneous system consisting of the ionic surfactant to be inspected, the water contg. the split-phase indicator forming a complex with the surfactant and water insoluble org. solvent as a liquid to be titrated and the surfactant having the charge reverse from the charge of the surfactant or the same charge as a titrating liquid, in a method for measuring the ionic surfactant by the split-phase titration. Any among orange I, Amaranth and New Coccine is used alone as the split-phase indicator. Two kinds of the dyes which is suitable for use under the alkaline condition and the acidic condition and are approximately equal in the wavelength of the absorption maximal are otherwise previously prepd. and the dyes suitable for the respective conditions are selectively used.