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公开(公告)号:JPH11302166A
公开(公告)日:1999-11-02
申请号:JP11198398
申请日:1998-04-22
Applicant: KAO CORP
Inventor: OCHIAI TATSUSHI , NAITO YUKIO , JOKURA HIROKO
IPC: A61K45/00 , A61K31/235 , A61K31/52 , A61K36/18 , A61K36/81 , A61P25/00 , A61P25/02 , A61P25/20 , A61P43/00 , A61K35/78
Abstract: PROBLEM TO BE SOLVED: To obtain the subject function improver effectively acting upon unidentified clinical syndrome symptoms such as systemic feebleness, fatigue, numbness of limb, shoulder stiffness and fatigue of eyes by combinedly using γ-oryzanol with a central nerve stimulator. SOLUTION: This function improver is obtained by combinedly using (A) γ-oryzanol with (B) a central nerve stimulator as active ingredients. The ingredient A is a generic term of agents included in nonsaponified materials in rice bran oil, having maximum absorbance at 231, 291 and 315 μm and a mixture of two or more kinds of unsaturated terpene alcohol-based ferulic acid esters. The ingredient B is preferably at least one selected from spicy ingredients of (i) ginger, (ii) capsicum and (iii) pepper and (iv) caffeine. This function improver is preferably used as a preparation for oral administration. The daily effective dose is preferably 1-500 mg ingredient A, 5-300 mg ingredient iv, 1 mg-50 g ingredient i, 0.1 mg-2 g ingredient ii and 0.1 mg-2 g ingredient iii.
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公开(公告)号:JPH0912481A
公开(公告)日:1997-01-14
申请号:JP18464095
申请日:1995-06-27
Applicant: TAIYO KAGAKU KK , KAO CORP
Inventor: KOBAYASHI TOSHINORI , HORIE KENJI , TANI NORIKO , FUJIKI MASARU , KIN BUSAKU , NAITO YUKIO , NOJIRI HIROSHI
IPC: A61K8/96 , A61K8/00 , A61K8/20 , A61K8/24 , A61K8/64 , A61K39/395 , A61Q5/02 , A61Q5/12 , A61Q11/00 , A61Q17/04 , A61K7/00 , A61K7/075 , A61K7/08 , A61K7/16 , A61K7/42
Abstract: PURPOSE: To easily obtain a quasi drug and a cosmetic containing a high purity γ-livetin maintaining its activity at a low cost by adding the γ-livetin purified by using a membrane under a specific condition. CONSTITUTION: These quasi drug and cosmetic are obtained by blending γ-livetin purified by adding a salt (preferably one kind or more selected from NaCl, KCl, CaCl2 , MgCl2 , NaH2 PO4 , Na2 HPO4 , KH2 PO4 and K2 HPO4 ) to a solution containing γ-livetin so as to become 0.7-3.0M concentration, preferably 1.5-2.0M, and then using a membrane having 90-500kDa fractionating molecular weight, preferably 100-300kDa (preferably an ultra-filtering membrane) under a condition at pH5.0-11.0, especially preferably at pH8.0-9.0. It is preferable that the aforementioned γ-livetin is a specific antibody to the hair. Further, the adding amount of the γ-livetin is preferably 0.001-50 pts.wt. based on the 100 pts.wt. quasi drug or cosmetic.
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公开(公告)号:JPH06298629A
公开(公告)日:1994-10-25
申请号:JP9140593
申请日:1993-04-19
Applicant: KAO CORP
Inventor: TANAMACHI HIROTO , NAITO YUKIO
IPC: A61K8/00 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/39 , A61K8/44 , A61Q5/00 , A61Q5/04 , A61K7/09
Abstract: PURPOSE:To obtain a hair deforming agent composition, comprising a specific organic acid such as a hydroxy-carboxylic acid and a permeation accelerator such as benzyl alcohol, assuming the acidity, excellent in high humidity resistance and capable of providing the hair deformation with high persistent effects without damaging vicious hair. CONSTITUTION:This hair deforming agent composition comprises one or more organic acids selected from DL-pyroglutamic acid, hydroxy-carboxylic acids, dicarboxylic acids and salts thereof and one or two or more permeation accelerators selected from benzyl alcohol, benzyloxyethanol and alkylene glycol monoalkyl ethers expressed by the formula [R is H or methyl; R is 1-5C alkyl; (m) is 1 or 2] and assumes the acidity. The composition preferably contains >=5wt.% organic acids and 1-30wt.% permeation accelerators. Furthermore, the hair deforming agent composition is preferably regulated to pH2.5-6, especially pH3-5. This composition is capable of simply making vicious hair into straight hair without damaging thereof.
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公开(公告)号:JPH0623087B2
公开(公告)日:1994-03-30
申请号:JP26368089
申请日:1989-10-09
Applicant: KAO CORP
Inventor: KAMETANI JUN , KOBAYASHI HISATAKA , TAKAHASHI TOSHE , IMAMURA TAKASHI , NAITO YUKIO
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公开(公告)号:JPH0552803B2
公开(公告)日:1993-08-06
申请号:JP23444587
申请日:1987-09-18
Applicant: KAO CORP
Inventor: NAITO YUKIO , OOSHIMA HISAMI , SAITO NORIKO
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公开(公告)号:JPH05139935A
公开(公告)日:1993-06-08
申请号:JP32505791
申请日:1991-11-14
Applicant: KAO CORP , TAIYO KAGAKU KK
Inventor: NOJIRI HIROSHI , NAITO YUKIO , TAKAHASHI HIDEHISA , FUJIKI MASARU , KIN BUSAKU
IPC: A61K8/00 , A61K8/64 , A61K8/98 , A61K39/395 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q7/00 , C07K16/00
Abstract: PURPOSE:To obtain a hair cosmetic providing hair with excellent conditioning effects such as moist feeling, flexibility, smoothness, prevention and restoration of split hair, gloss, etc., even in a dry state, not losing the effects even after shampoo several times. CONSTITUTION:A hair cosmetic containing about 0.01-50wt.%, preferably 0.01-20wt.% freeze-dried substance of egg yolk antibody (hair egg yolk antibody) obtained from eggs of domestic fowl immunized against hair such as powder prepared by grinding whole hair of healthy hair or damaged hair by permanent wave, etc., or hair constituent tissue into
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公开(公告)号:JPH0250881B2
公开(公告)日:1990-11-05
申请号:JP1642181
申请日:1981-02-06
Applicant: KAO CORP
Inventor: NEMOTO TOSHUKI , NAITO YUKIO , IKEDA YASUHIRO , TSUSHIMA RIKIO
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公开(公告)号:JPS6475411A
公开(公告)日:1989-03-22
申请号:JP23444587
申请日:1987-09-18
Applicant: KAO CORP
Inventor: NAITO YUKIO , OSHIMA HISAMI , SAITO NORIKO
Abstract: PURPOSE:To provide the titled treatment agent containing a specific cysteine derivative and a cationic polymer, having a specific pH range and capable of forming a semipermanent wave to hair by heating the hair coated with the agent and of semipermanently improving the feeling of the hair. CONSTITUTION:The hair-treatment agent contains (A) a cysteine derivative selected from the compounds of formula (R1 is H or 1-3C acyl), e.g. N-acetyl-3- mercaptoalanine and glutathione and (B) a cationic polymer such as quaternary derivative of cellulose ester, copolymer of vinyl pyrrolidone or polylysine and is adjusted to pH 7-9. The amounts of the components A and B are 0.1-5.0wt.% and 0.01-30.0wt.% especially 0.5-3.0wt.% and 0.1-10.0wt.%, respectively. 10-150ml of the agent is applied to the hair at a time and the hair is heated at 40-160 deg.C, preferably 40-80 deg.C.
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公开(公告)号:JPS62205014A
公开(公告)日:1987-09-09
申请号:JP4691786
申请日:1986-03-04
Applicant: KAO CORP
Inventor: NAITO YUKIO , OOSHIMA HISAMI
Abstract: PURPOSE:A hair deformation treating agent, containing a 3-mercapto-2- hydroxypropyltrialkylammonium salt as a principal ingredient and capable of forming firm waves in the hair at a relatively low temperature in a relatively short time by simple operation. CONSTITUTION:A hair deformation treating agent, containing a compound, expressed by the formula (R1 is 1-12C alkyl; R2 and R3 are alkyl; X is halogen) and having stable and high waving effect, e.g. 3-mercapto-2- hydroxypropyltrimethylammonium chloride, etc., as a principal ingredient and useful as the first solution of a two-bath cold permanent wave solution or heating type one-bath permanent wave solution. Since the above-mentioned treating agent has the above-mentioned effect and particularly no alkali agent or reducing substance and oxidizing substance in a high concentration are used in the heating type one-bath permanent wave solution, damage of the hair caused by elution of hair proteins can be reduced and the storage stability is good with slight irritancy to the skin.
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