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公开(公告)号:EP0294491A4
公开(公告)日:1990-06-28
申请号:EP88900128
申请日:1987-12-21
Applicant: KAO CORP
Inventor: IWASAKI TETSUJI , UESAKA TOSHIO
CPC classification number: C12P1/04 , C12R1/38 , Y10S435/874
Abstract: New antibiotic Y1-HU3 has the following characteristics: (a) mol. wt. 469; (b) m.pt. 180-190oC, pale yellow crystals; (c) UV spectrum has two maxima at 312 nm and 300 nm (in chloroform); (d) soluble in methanol, chloroform; (e) insol. in n-hexane. The IR, 1H NMR and 13C NMR spectra are given. Antiobiotic Y1-HU3 is obtd. by culture of Pseudomonas species Y1-Hu (FERM-BP 1610). In an example Pseudomonas sp. Y1-HU is cultured in potato dextrose medium at pH and 28 deg. C for four days. The cell bodies are sepd. and the culture filtrate extracted with chloroform. The extract is concd. and chromatographed on silica gel (Wakogel C-200) using chloroform as eluent. The produce is dissolved in chloroform/methanol and hexane added to give antibiotic Y1-HU (10 mg from 1 litre culutre).
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公开(公告)号:AU2006316123A1
公开(公告)日:2007-05-24
申请号:AU2006316123
申请日:2006-11-17
Applicant: KAO CORP
Inventor: UESAKA TOSHIO , UMEHARA MASAHIRO , SUGAWARA SATOSHI , SAKUMA YASUMITSU , INOMATA YUKIO
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公开(公告)号:DE69626629D1
公开(公告)日:2003-04-17
申请号:DE69626629
申请日:1996-10-15
Applicant: KAO CORP
Inventor: NAKAJIMA ATSUSHI , FUKUDA MASATAKA , MORITA TAKESHI , UESAKA TOSHIO , SADAHIRO TOMOKO
IPC: A61K8/34 , A61K8/36 , A61K8/365 , A61K8/43 , A61K8/68 , A61K8/97 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q19/00 , A61Q19/08 , A61K7/48 , A61K7/06
Abstract: The present invention relates to cosmetic compositions comprising (A) at least one amide derivative having a specified formula; and (B) at least one ingredient selected from the group consisting of (B-1) polyhydric alcohols, (B-2) vegetable extracts and (B-3) organic acids or salts thereof. The compositions can enhance the water-retaining ability of the horny layer and have excellent effects for improving skin roughness and preventing the formation of wrinkles.
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公开(公告)号:DE3786795D1
公开(公告)日:1993-09-02
申请号:DE3786795
申请日:1987-12-21
Applicant: KAO CORP
Inventor: IWASAKI TETSUJI , UESAKA TOSHIO
Abstract: New antibiotic Y1-HU3 has the following characteristics: (a) mol. wt. 469; (b) m.pt. 180-190oC, pale yellow crystals; (c) UV spectrum has two maxima at 312 nm and 300 nm (in chloroform); (d) soluble in methanol, chloroform; (e) insol. in n-hexane. The IR, 1H NMR and 13C NMR spectra are given. Antiobiotic Y1-HU3 is obtd. by culture of Pseudomonas species Y1-Hu (FERM-BP 1610). In an example Pseudomonas sp. Y1-HU is cultured in potato dextrose medium at pH and 28 deg. C for four days. The cell bodies are sepd. and the culture filtrate extracted with chloroform. The extract is concd. and chromatographed on silica gel (Wakogel C-200) using chloroform as eluent. The produce is dissolved in chloroform/methanol and hexane added to give antibiotic Y1-HU (10 mg from 1 litre culutre).
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公开(公告)号:DE60111459D1
公开(公告)日:2005-07-21
申请号:DE60111459
申请日:2001-02-23
Applicant: KAO CORP
Inventor: HOSOKAWA MASARU , SHIMIZU KUMIKO , UESAKA TOSHIO , SUGAI ICHIRO , MORI SHINOBU
IPC: A61K9/06 , A61K9/70 , A61K47/30 , A61K9/00 , A61K9/08 , A61K9/10 , A61K9/107 , A61K47/34 , A61K47/32 , A61K47/36 , A61K47/38 , A61K31/665
Abstract: Provided is a composition for percutaneous administration containing a mixture of polymers forming a surface-segregated film, and (B) an active ingredient. The composition provides excellent percutaneous absorption efficacy of the active ingredient, particularly, a water-soluble active ingredient, has excellent feeling and is convenient to use.
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公开(公告)号:AU2006316123B2
公开(公告)日:2012-03-01
申请号:AU2006316123
申请日:2006-11-17
Applicant: KAO CORP
Inventor: UESAKA TOSHIO , UMEHARA MASAHIRO , SUGAWARA SATOSHI , SAKUMA YASUMITSU , INOMATA YUKIO
Abstract: Provided are a cosmetic composition which is an O/W/O emulsion composition and contains, in the oil phases O and O thereof, fine metal oxide particles having ultraviolet screening ability; and a preparation process of the cosmetic composition.
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公开(公告)号:AU2006316121A1
公开(公告)日:2007-05-24
申请号:AU2006316121
申请日:2006-11-17
Applicant: KAO CORP
Inventor: SAKUMA YASUMITSU , INOMATA YUKIO , UESAKA TOSHIO , SUGAWARA SATOSHI , UMEHARA MASAHIRO
Abstract: Provided is an O/W emulsion cosmetic composition, which contains the following components (A), (B) and (C): (A) a polymer which is either a nonionic or cationic polymer composed of a hydrophobic monomer unit and a hydrophilic monomer unit and contains from 40 to 80 wt. % of a hydrophilic group; (B) a dispersion containing the following components (a), (b), (c) and (d): (a) powders having ultraviolet screening ability and having a surface subjected to hydrophobic treatment, (b) a polymer composed of a hydrophobic monomer unit and a hydrophilic monomer unit, (c) a silicone oil, and (d) an alcohol having from 1 to 3 carbon atoms, at an (a):(b):(c):(d) weight ratio of (from 25 to 65):(from 0.1 to 5):(from 10 to 50):(from 10 to 50); and (C) water.
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公开(公告)号:DE60111459T2
公开(公告)日:2006-05-11
申请号:DE60111459
申请日:2001-02-23
Applicant: KAO CORP
Inventor: HOSOKAWA MASARU , SHIMIZU KUMIKO , UESAKA TOSHIO , SUGAI ICHIRO , MORI SHINOBU
IPC: A61K9/00 , A61K9/06 , A61K9/08 , A61K9/10 , A61K9/107 , A61K9/70 , A61K31/665 , A61K47/30 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38
Abstract: Provided is a composition for percutaneous administration containing a mixture of polymers forming a surface-segregated film, and (B) an active ingredient. The composition provides excellent percutaneous absorption efficacy of the active ingredient, particularly, a water-soluble active ingredient, has excellent feeling and is convenient to use.
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公开(公告)号:DE69626629T2
公开(公告)日:2004-02-05
申请号:DE69626629
申请日:1996-10-15
Applicant: KAO CORP
Inventor: NAKAJIMA ATSUSHI , FUKUDA MASATAKA , MORITA TAKESHI , UESAKA TOSHIO , SADAHIRO TOMOKO
IPC: A61K8/34 , A61K8/36 , A61K8/365 , A61K8/43 , A61K8/68 , A61K8/97 , A61Q5/00 , A61Q5/02 , A61Q5/06 , A61Q19/00 , A61Q19/08 , A61K7/48 , A61K7/06
Abstract: The present invention relates to cosmetic compositions comprising (A) at least one amide derivative having a specified formula; and (B) at least one ingredient selected from the group consisting of (B-1) polyhydric alcohols, (B-2) vegetable extracts and (B-3) organic acids or salts thereof. The compositions can enhance the water-retaining ability of the horny layer and have excellent effects for improving skin roughness and preventing the formation of wrinkles.
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公开(公告)号:AU2006316121B2
公开(公告)日:2012-03-08
申请号:AU2006316121
申请日:2006-11-17
Applicant: KAO CORP
Inventor: SAKUMA YASUMITSU , INOMATA YUKIO , UESAKA TOSHIO , SUGAWARA SATOSHI , UMEHARA MASAHIRO
Abstract: Provided is an O/W emulsion cosmetic composition, which contains the following components (A), (B) and (C): (A) a polymer which is either a nonionic or cationic polymer composed of a hydrophobic monomer unit and a hydrophilic monomer unit and contains from 40 to 80 wt.% of a hydrophilic group; (B) a dispersion containing the following components (a), (b), (c) and (d): (a) powders having ultraviolet screening ability and having a surface subjected to hydrophobic treatment, (b) a polymer composed of a hydrophobic monomer unit and a hydrophilic monomer unit, (c) a silicone oil, and (d) an alcohol having from 1 to 3 carbon atoms, at an (a):(b):(c):(d) weight ratio of (from 25 to 65):(from 0.1 to 5):(from 10 to 50):(from 10 to 50); and (C) water.
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