公开(公告)号：WO2019009593A2

公开(公告)日：2019-01-10

申请号：PCT/KR2018/007526

申请日：2018-07-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： CHUNG, Hak Suk ,  JI, Yu Hyun ,  AN, Jin Su ,  KWON, Ick Chan ,  YANG, Eun Gyeong

IPC: C12N15/74 ,  C12N9/14 ,  C12N9/16 ,  C12P19/04

Abstract: A bacterium that constitutively produces monophosphoryl lipid A (MLA) and a method of producing MLA by using the bacterium may simply produce MLA and a derivative thereof without acid hydrolysis, reduce a probability of natural mutation, and increase yields of MLA and a derivative thereof by constitutive expression of the MLA and derivative thereof.