公开(公告)号：US11064900B2

公开(公告)日：2021-07-20

申请号：US16085488

申请日：2017-04-03

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Seong-Joo Lee ,  Kiwoong Kim ,  Jeong-Hyun Shim ,  Kwon-Kyu Yu ,  Seong-min Hwang

IPC: A61B5/055 ,  G01R33/48 ,  G01R33/381 ,  G01R33/32 ,  G01R33/56 ,  A61B5/00 ,  G01R33/24 ,  G01R33/44 ,  G01R33/421

Abstract: Provided are an ultra-low field nuclear magnetic resonance device and a method for measuring an ultra-low field nuclear resonance image. The ultra-low field nuclear magnetic resonance device includes an AC power supply configured to supply a current to a measurement target in such a manner the current flows to the measurement target, magnetic field measurement means disposed adjacent to the measurement target, and measurement bias magnetic field generation means configured to apply a measurement bias magnetic field corresponding to a proton magnetic resonance frequency of the measurement target. A vibration frequency of the AC power supply matches the proton magnetic resonance frequency of the measurement target, and the magnetic field measurement means measures a nuclear magnetic resonance signal generated from the measurement target.

公开(公告)号：US20150268311A1

公开(公告)日：2015-09-24

申请号：US14692258

申请日：2015-04-21

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Kwon-Kyu Yu ,  Yong-Ho Lee ,  Kiwoong Kim ,  Hyukchan Kwon ,  Jin-Mok Kim ,  Sang-Kil Lee

IPC: G01R33/00 ,  H01L39/02 ,  H01L23/367 ,  G01R1/18 ,  G01R33/035 ,  H01L23/473

CPC classification number: G01R33/007 ,  A61B5/04005 ,  A61B5/05 ,  G01R1/18 ,  G01R33/035 ,  G01R33/0354 ,  H01L23/367 ,  H01L23/473 ,  H01L39/02 ,  H01L2924/0002 ,  H01L2924/00

Abstract: An apparatus and a method for indirectly cooling a superconducting quantum interference device (SQUID) are provided. The apparatus includes an outer container extending in a vertical direction; a metallic inner container inserted into the outer container to store a liquid coolant, the metal inner container including a top plate; a SQUID sensor module disposed between a bottom surface of the outer container and a bottom surface of the inner container; a heat transfer pillar adapted to cool the SQUID sensor module, the heat transfer pillar having one end connected to the bottom surface of the inner container and the other end directly or indirectly connected to the SQUID sensor module; a magnetic shield part formed of a superconductor covering a top surface of the SQUID sensor module; and a heat conduction plate being in thermal contact with the other end of the heat transfer pillar.

Abstract translation: 提供了用于间接冷却超导量子干涉装置（SQUID）的装置和方法。 该装置包括沿垂直方向延伸的外容器; 插入外容器中以存储液体冷却剂的金属内容器，金属内容器包括顶板; 设置在所述外容器的底面和所述内容器的底面之间的SQUID传感器模块; 传热柱，用于冷却SQUID传感器模块，传热柱的一端连接到内容器的底表面，另一端直接或间接地连接到SQUID传感器模块; 由覆盖SQUID传感器模块的顶表面的超导体形成的磁屏蔽部分; 并且导热板与传热柱的另一端热接触。

公开(公告)号：US10162028B2

公开(公告)日：2018-12-25

申请号：US14618535

申请日：2015-02-10

Applicant: Korea Research Institute of Standards and Science

Inventor： Seong-min Hwang ,  Kiwoong Kim ,  Kwon-Kyu Yu ,  Seong-Joo Lee ,  Jeong-Hyun Shim

IPC: G01R33/44 ,  G01R33/3815 ,  G01R33/32 ,  G01R33/34

Abstract: Provided is a low magnetic field and ultra-low magnetic field NMR and MRI apparatus. The low magnetic field and ultra-low magnetic field NMR and MRI apparatus includes a SQUID sensor and a prepolarization magnetic field coil. The prepolarization magnetic field coil generates a prepolarization magnetic field to polarize a sample. The prepolarization magnetic coil generates a counter pulse in a direction opposite to that of the prepolarization magnetic field immediately before or immediately after the prepolarization magnetic field is generated. The counter pulse demagnetizes wanted magnetization including that of the prepolarization magnetic field coil itself.

公开(公告)号：US09759793B2

公开(公告)日：2017-09-12

申请号：US14262251

申请日：2014-04-25

Applicant: Korea Research Institute of Standards and Science

Inventor： Kiwoong Kim ,  Chan-Seok Kang ,  Seong-Joo Lee ,  Yong-ho Lee ,  Kwon-Kyu Yu

IPC: G01V3/00 ,  G01R33/44 ,  G01N24/08 ,  G01R33/32

CPC classification number: G01R33/448 ,  G01N24/08 ,  G01R33/326 ,  G01R33/445

Abstract: Provided are an object discrimination method and an object discrimination apparatus using an ultra-low magnetic field nuclear magnetic resonance (NMR). The method includes measuring the respective spin-lattice relaxation times at a plurality of strengths of prepolarization magnetic fields with respect to a measurement target and classifying the measurement target using the spin-lattice relaxation times.

公开(公告)号：US20160209482A1

公开(公告)日：2016-07-21

申请号：US14618535

申请日：2015-02-10

Applicant: Korea Research Institute of Standards and Science

Inventor： Seong-min Hwang ,  Kiwoong Kim ,  Kwon-Kyu Yu ,  Seong-Joo Lee ,  Jeong-Hyun Shim

IPC: G01R33/44 ,  G01R33/3815 ,  G01R33/32

CPC classification number: G01R33/445 ,  G01R33/326 ,  G01R33/34023 ,  G01R33/3815

Abstract: Provided is a low magnetic field and ultra-low magnetic field NMR and MRI apparatus. The low magnetic field and ultra-low magnetic field NMR and MRI apparatus includes a SQUID sensor and a prepolarization magnetic field coil. The prepolarization magnetic field coil generates a prepolarization magnetic field to polarize a sample. The prepolarization magnetic coil generates a counter pulse in a direction opposite to that of the prepolarization magnetic field immediately before or immediately after the prepolarization magnetic field is generated. The counter pulse demagnetizes wanted magnetization including that of the prepolarization magnetic field coil itself.

Abstract translation: 提供了低磁场和超低磁场NMR和MRI装置。 低磁场和超低磁场NMR和MRI装置包括SQUID传感器和预极化磁场线圈。 预极化磁场线圈产生极化磁极以使样品极化。 前极化磁线圈在产生前极化磁场之前或之后产生与反极化磁场相反方向的计数脉冲。 计数脉冲使包括预极化磁场线圈本身的所需磁化消磁。

公开(公告)号：US12245857B2

公开(公告)日：2025-03-11

申请号：US17853769

申请日：2022-06-29

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Kwon-Kyu Yu ,  Yong-Ho Lee ,  Hyukchan Kwon ,  Jin-Mok Kim ,  Sang-Kil Lee ,  Bokyung Kim ,  Min-Young Kim ,  Kiwong Kim

IPC: A61B5/245 ,  A61B5/00 ,  G01R33/00 ,  G01R33/035

Abstract: A dual-helmet magnetoencephalography measuring apparatus includes: an internal container storing a liquid refrigerant; an external container disposed to surround the internal container and including a first external helmet and a second external helmet disposed to be spaced apart from each other; a first sensor-mounted helmet disposed to surround the first external helmet between the external container and the internal container; a second sensor-mounted helmet disposed to surround the second external helmet between the externa container and the internal container; a plurality of first SQUID sensor module disposed on the first sensor-mounted helmet; and a plurality of second SQUID sensor module disposed on the second sensor-mounted helmet.

公开(公告)号：US10585151B2

公开(公告)日：2020-03-10

申请号：US15097912

申请日：2016-04-13

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Kwon-Kyu Yu ,  Yong-Ho Lee ,  Kiwoong Kim ,  Jin-Mok Kim ,  Hyukchan Kwon ,  Sang-Kil Lee

IPC: A61B5/00 ,  G01R33/035 ,  A61B5/04 ,  G01R33/00 ,  G01R33/022

Abstract: Superconducting quantum interference device (SQUID) sensor module and a magnetoencephalography (MEG) measuring apparatus. The SQUID sensor module includes a fixed block having one end fixed to the sensor-mounted helmet, a bobbin having one end combined with the other end of the fixed block and having a groove in which a pick-up coil is wound, a bobbin fixing or attachment structure or material fixed to the other end of the fixed block via a through-hole formed in the center of the bobbin, a SQUID printed circuit board (PCB) disposed one an upper side surface of the bobbin and including a SQUID sensor, and a signal line connection PCB inserted into an outer circumferential surface of the fixed block and adapted to transmit a signal detected in the SQUID sensor to an external circuit.

公开(公告)号：US20150226813A1

公开(公告)日：2015-08-13

申请号：US14692294

申请日：2015-04-21

Applicant: Korea Research Institute of Standards and Science

Inventor： Kwon-Kyu Yu ,  Yong-Ho Lee ,  Hyukchan Kwon ,  Jin-Mok Kim ,  Kiwoong Kim ,  Sang-Kil Lee

IPC: G01R33/035 ,  G01R33/00

CPC classification number: G01R33/0354 ,  A61B5/04005 ,  A61B5/05 ,  G01R33/0047 ,  G01R33/0082 ,  H05K7/02

Abstract: Provided are a low-temperature cooling apparatus and a superconducting quantum interference device (SQUID) sensor module. The low-temperature cooling apparatus includes an outer container; an inner container disposed inside the outer container, the inner container including a neck portion having a first diameter and a body portion having a second diameter greater than the first diameter; an insert inserted into the neck portion of the inner container; and a plurality of SQUID sensor modules inserted into the body portion of the inner container. Each of the SQUID sensor modules is in the form of a fan-shaped pillar and is fixedly coupled with an inner bottom plate of the inner container.

Abstract translation: 提供低温冷却装置和超导量子干涉装置（SQUID）传感器模块。 低温冷却装置包括外容器; 内部容器，其设置在所述外部容器的内部，所述内部容器包括具有第一直径的颈部部分和具有大于所述第一直径的第二直径的主体部分; 插入到所述内部容器的颈部中的插入件; 以及插入到所述内部容器的主体部分中的多个SQUID传感器模块。 每个SQUID传感器模块都是扇形柱的形式，并与内部容器的内底板固定连接。

公开(公告)号：US20140235996A1

公开(公告)日：2014-08-21

申请号：US14260750

申请日：2014-04-24

Applicant: Korea Research Institute of Standards and Science

Inventor： Kiwoong Kim ,  Hyukchan Kwon ,  Yong-Ho Lee ,  Kwon-Kyu Yu ,  Jin-Mok Kim

IPC: A61B5/04 ,  A61B6/03 ,  A61B5/055

CPC classification number: A61B5/04011 ,  A61B5/04007 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/0522 ,  A61B5/055 ,  A61B6/03 ,  G16H50/50

Abstract: A method for mapping of myocardial electric activity includes measuring electrocardiogram data or magnetocardiogram data and mapping the degree of electric activity of a myocardial surface using the electrocardiogram data or the magnetocardiogram data. A signal source of the electrocardiogram data or the magnetocardiogram data is a myocardial surface potential that is scalar quantity. The mapping uses a lead-field vector which represents the sensitivity between the myocardial surface potential and the electrocardiogram or magnetocardiogram data, and a modified lead-field vector which combines a constraint matrix with a constraint condition where no potential sources exist in a specific region.

Abstract translation: 用于映射心肌电活动的方法包括使用心电图数据或心电图数据测量心电图数据或磁心图数据并映射心肌表面的电活动程度。 心电图数据或心电图数据的信号源是标量量的心肌表面电位。 映射使用表示心肌表面电位和心电图或磁心图数据之间的灵敏度的引导场向量，以及将约束矩阵与在特定区域中不存在潜在源的约束条件组合的修改的引线域向量。

公开(公告)号：US09921280B2

公开(公告)日：2018-03-20

申请号：US14446764

申请日：2014-07-30

Applicant: Korea Research Institute of Standards and Science

Inventor： Kiwoong Kim ,  Yong-ho Lee ,  Seong-Joo Lee ,  Kwon-Kyu Yu

IPC: A61B5/055 ,  G01R33/385 ,  G01R33/32 ,  G01R33/26 ,  G01R33/48 ,  A61B5/05 ,  G01R33/44

CPC classification number: G01R33/385 ,  A61B5/05 ,  A61B5/055 ,  G01R33/26 ,  G01R33/326 ,  G01R33/445 ,  G01R33/48 ,  G01R33/4806

Abstract: Provided are an ultra-low-field nuclear magnetic resonance device and an ultra-low-field nuclear magnetic resonance measuring method. The method includes applying a first measurement bias magnetic field corresponding to an excitation frequency of a coherent biomagnetic field generated in association with the electrophysiological activity of human body organs, applying a second measurement bias magnetic field having the same direction as the first measurement bias magnetic field and having a different magnitude than the first measurement bias magnetic field, and measuring a magnetic resonance signal generated in the human body by using magnetic field measuring means.