公开(公告)号：US10889794B2

公开(公告)日：2021-01-12

申请号：US14385829

申请日：2012-12-27

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS

Inventor： Sung-Kyu Seo ,  Geon-Soo Jin ,  Un-Hwan Ha ,  Se-Hwan Paek ,  Seung-Pil Pack

IPC: G01N21/01 ,  G01N33/487 ,  G01J1/02 ,  C12M1/34

Abstract: The present invention relates to an apparatus that uses shadow images of cells to continuously measure cell activity at a high processing rate in order to provide cell activity and cell number results. According to one embodiment of the present invention, instead of a highly experienced examiner or technician using a microscope, ELISA reader, etc. having to collect various cell activity measurements and cell numbers, the collection of said information can be automated so as to reduce cost and largely reduce errors in measurements through the development of computer software coupled with hardware using low cost and compact optoelectronic components and simple image processing techniques.

公开(公告)号：US20150338350A1

公开(公告)日：2015-11-26

申请号：US14650056

申请日：2013-11-25

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Sung-Kyu Seo ,  Un-Hwan Ha

IPC: G01N21/84 ,  G01N33/487

CPC classification number: G01N21/8422 ,  G01N21/00 ,  G01N33/4875 ,  G01N33/48785 ,  G01N2201/061

Abstract: The present invention relates to a device for monitoring a biofilm, which can monitor a formation state of the biofilm by using a biofilm shadow image. According to one embodiment of the present invention, the device for monitoring a biofilm can comprise: a water tank for storing water; a monitoring substrate arranged inside the water tank and surface-treated so as to accelerate the biofilm formation; a light-emitting module located at an upper portion of the monitoring substrate so as to emit light in a monitoring substrate direction; and an image sensor unit arranged below the monitoring substrate so as to capture a shadow image of the biofilm, which is formed on the monitoring substrate.

Abstract translation: 本发明涉及用于监测生物膜的装置，其可以通过使用生物膜阴影图像来监测生物膜的形成状态。 根据本发明的一个实施例，用于监测生物膜的装置可以包括：用于储存水的水箱; 监测基板，布置在水箱内部并进行表面处理，以加速生物膜形成; 位于监视基板的上部的发光模块，以便在监视基板方向上发光; 以及图像传感器单元，其布置在所述监视基板的下方，以捕获形成在所述监视基板上的所述生物膜的阴影图像。

公开(公告)号：US10018568B2

公开(公告)日：2018-07-10

申请号：US14650056

申请日：2013-11-25

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS

Inventor： Sung-Kyu Seo ,  Un-Hwan Ha

IPC: C12M1/00 ,  G01N21/00 ,  G01N33/00 ,  G01N21/84 ,  G01N33/487

CPC classification number: G01N21/8422 ,  G01N21/00 ,  G01N33/4875 ,  G01N33/48785 ,  G01N2201/061

Abstract: The present invention relates to a device for monitoring a biofilm, which can monitor a formation state of the biofilm by using a biofilm shadow image. According to one embodiment of the present invention, the device for monitoring a biofilm can comprise: a water tank for storing water; a monitoring substrate arranged inside the water tank and surface-treated so as to accelerate the biofilm formation; a light-emitting module located at an upper portion of the monitoring substrate so as to emit light in a monitoring substrate direction; and an image sensor unit arranged below the monitoring substrate so as to capture a shadow image of the biofilm, which is formed on the monitoring substrate.

公开(公告)号：US20150050684A1

公开(公告)日：2015-02-19

申请号：US14385829

申请日：2012-12-27

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Sung-Kyu Seo ,  Geon-Soo Jin ,  Un-Hwan Ha ,  Se-Hwan Paek ,  Seung-Pil Pack

IPC: G01N33/487 ,  G01J1/02 ,  G01N21/01

CPC classification number: C12M41/46 ,  G01J1/0295

Abstract: The present invention relates to an apparatus that uses shadow images of cells to continuously measure cell activity at a high processing rate in order to provide cell activity and cell number results. According to one embodiment of the present invention, instead of a highly experienced examiner or technician using a microscope, ELISA reader, etc. having to collect various cell activity measurements and cell numbers, the collection of said information can be automated so as to reduce cost and largely reduce errors in measurements through the development of computer software coupled with hardware using low cost and compact optoelectronic components and simple image processing techniques.

Abstract translation: 本发明涉及使用细胞的阴影图像以高处理速率连续测量细胞活性以便提供细胞活性和细胞数目结果的装置。 根据本发明的一个实施方案，代替使用显微镜，ELISA读取器等的经验丰富的检验者或技术人员必须收集各种细胞活性测量值和细胞数量，可以自动地收集所述信息以降低成本 并通过开发与硬件相结合的计算机软件，通过低成本，紧凑的光电子元件和简单的图像处理技术，大大减少了测量误差。