公开(公告)号：EP1113791A2

公开(公告)日：2001-07-11

申请号：EP98951778.4

申请日：1998-10-20

Applicant: Korea Institute of Science and Technology

Inventor： BOK, Song, Hae ,  JEONG, Tae, Sook ,  CHOI, Myung, Sook ,  MOON, Surk, Sik ,  KWON, Yong, Kook ,  LEE, Eun, Sook ,  HYUN, Byung, Hwa ,  CHOI, Yang, Kyu ,  LEE, Chul, Ho ,  AHN, Byung, Tae ,  LEE, Sae, Bom ,  BAE, Ki, Hwan ,  PARK, Yong, Bok

IPC: A61K31/35 ,  A61K31/70 ,  A23L2/56

CPC classification number: A61K31/34 ,  Y10S514/866

Abstract: A use of bioflavonoid of formula (I) or a plant extract containing same for lowering the blood glucose level in a mammal.

公开(公告)号：EP1123096A1

公开(公告)日：2001-08-16

申请号：EP98951779.2

申请日：1998-10-20

Applicant: Korea Institute of Science and Technology

Inventor： BOK, Song, Hae ,  JEONG, Tae, Sook ,  CHOI, Myung, Sook ,  MOON, Surk, Sik ,  KWON, Yong, Kook ,  LEE, Eun, Sook ,  HYUN, Byung, Hwa ,  CHOI, Yang, Kyu ,  LEE, Chul, Ho ,  AHN, Byung, TaeBella Apt. C-105 ,  LEE, Sae, Bom ,  KIM, Sung, Gyu ,  MOON, Og, Sung ,  PARK, Yong, Bok

IPC: A61K31/353 ,  A61K35/78

Abstract: A use of a bioflavonoid of formula (I) or plant extract containing same for increasing the plasma high density lipoprotein (HDL) level in a mammal, wherein, R?1, R2, R3, R4, R5, R6, R7, R8 and R9¿ are each independently hydrogen; a hydroxy group; a C¿1-9? alkoxy group optionally substituted with one or more substituents selected from the group consisting of a hydroxy, C1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amide group; a C5-9 cycloalkyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C5-9 cycloalkylcarbonyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C2-10 or C16-18 acyloxy group optionally substituted with one or more substituents selected from the group consisting of a hydroxy, C1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen and nitro group; a rutinosyl group; or a rhaminosyl group; and X is a single or double bond.