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Patent Agency Ranking1.发明申请STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF 审中-公开作为抗坏血酸纤维素形成的抑制剂的苯乙烯苯并呋喃衍生物及其制备方法
公开(公告)号：WO2009151299A2
公开(公告)日：2009-12-17
申请号：PCT/KR2009/003165
申请日：2009-06-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , HANMI PHARM. CO., LTD. , KIM, Dong Jin , YOO, Kyung Ho , BYUN, Ji Hun , KIM, YoungSoo , KIM, Hye Yun , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , LEE, Ji Hoon , LEE, Myoung-Hwan , HWANG, Hana , RYU, Jiyeon
Inventor： KIM, Dong Jin , YOO, Kyung Ho , BYUN, Ji Hun , KIM, YoungSoo , KIM, Hye Yun , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , LEE, Ji Hoon , LEE, Myoung-Hwan , HWANG, Hana , RYU, Jiyeon
IPC: C07D307/78
CPC classification number: C07D307/81 , C07D307/80
Abstract: The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
Abstract translation: 本发明涉及有效抑制脑中β-淀粉样蛋白原纤维形成以用于预防或治疗退行性脑病的新型化合物，其制备方法和含有该衍生物作为活性成分的药物组合物。
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2.发明申请COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开用于抑制形成β-淀粉样纤维的化合物，其制备方法和包含其的药物组合物
公开(公告)号：WO2008030072A1
公开(公告)日：2008-03-13
申请号：PCT/KR2007/004364
申请日：2007-09-10
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , HANMI PHARM. CO., LTD. , KIM, Dong Chan , KIM, Dong Jin , YOO, Kyung Ho , SHIN, Kye Jung , BYEON, Seong Rim , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , MOOK, Inhee
Inventor： KIM, Dong Chan , KIM, Dong Jin , YOO, Kyung Ho , SHIN, Kye Jung , BYEON, Seong Rim , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , MOOK, Inhee
IPC: C07D213/34
CPC classification number: C07D213/38 , C07D213/30
Abstract: The present invention relates to a novel compound which is effective in inhibiting the formation of beta-amyloid fibril in the brain, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
Abstract translation: 本发明涉及一种有效抑制脑中β-淀粉样蛋白原纤维形成的新型化合物及其制备方法，以及含有作为活性成分的药物组合物。
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3.发明申请
公开(公告)号：WO2005121144A1
公开(公告)日：2005-12-22
申请号：PCT/KR2005/001798
申请日：2005-06-14
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , YOO, Kyung Ho , KIM, Dong Jin , KANG, Yong Koo , LEE, Kyung Seok , LEE, Gwan Sun , KIM, Maeng Sup , KANG, Jae Hoon
Inventor： YOO, Kyung Ho , KIM, Dong Jin , KANG, Yong Koo , LEE, Kyung Seok , LEE, Gwan Sun , KIM, Maeng Sup , KANG, Jae Hoon
IPC: C07D477/20
CPC classification number: C07D477/20
Abstract: The present invention relates to a novel 1β-methylcarbapenem derivative, a process for the preparation thereof and a pharmaceutical composition comprising the 1β-methylcarbapenem derivative or a pharmaceutically acceptable salt thereof as an active antibacterial ingredient.
Abstract translation: 本发明涉及一种新型的β-甲基碳青霉烯类衍生物，其制备方法和药物组合物，其包含作为活性抗菌成分的β-甲基碳青霉烯衍生物或其药学上可接受的盐。
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4.发明公开
公开(公告)号：EP1765822A1
公开(公告)日：2007-03-28
申请号：EP05753525.4
申请日：2005-06-14
Applicant: Korea Institute of Science and Technology
Inventor： YOO, Kyung Ho, Gunyoung Apt. 104-1501 , KIM, D. J., Taereung Hyundai Hometwn Sweet 104-306 , KANG, Yong Koo, Gunyoung 3-cha Apt. , LEE, Kyung Seok , LEE, Gwan Sun , KIM, Maeng Sup , KANG, Jae Hoon
IPC: C07D477/20
CPC classification number: C07D477/20
Abstract: The present invention relates to a novel 1β-methylcarbapenem derivative, a process for the preparation thereof and a pharmaceutical composition comprising the 1β-methylcarbapenem derivative or a pharmaceutically acceptable salt thereof as an active antibacterial ingredient.
Abstract translation: 本发明涉及一种新的1β-甲基碳代青霉烯衍生物，其制备方法和含有1β-甲基碳代青霉烯衍生物或其药学上可接受的盐作为活性抗菌成分的药物组合物。
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5.发明公开STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF 审中-公开作为β-淀粉样蛋白纤维形成抑制剂的STYRYLBENZOFURAN衍生物及其制备方法
公开(公告)号：EP2291364A2
公开(公告)日：2011-03-09
申请号：EP09762685.7
申请日：2009-06-12
Inventor： KIM, Dong Jin , YOO, Kyung Ho , BYUN, Ji Hun , KIM, YoungSoo , KIM, Hye Yun , LEE, Gwan Sun , KIM, Maeng Sup , AHN, Young Gil , LEE, Ji Hoon , LEE, Myoung-Hwan , HWANG, Hana , RYU, Jiyeon
IPC: C07D307/78 , A61K31/343
CPC classification number: C07D307/81 , C07D307/80
Abstract: The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
Abstract translation: 本发明涉及有效抑制脑中β-淀粉样原纤维形成以用于预防或治疗退行性脑疾病的新型化合物，其制备方法，以及包含其作为活性成分的药物组合物。
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