公开(公告)号：US11992297B2

公开(公告)日：2024-05-28

申请号：US17164686

申请日：2021-02-01

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Ik Hwan Kwon ,  Tae Geol Lee ,  Sang Won Lee

IPC: A61B5/00 ,  A01K1/03 ,  A01K61/00 ,  A61B5/024 ,  A61D3/00 ,  G03H1/04

CPC classification number: A61B5/024 ,  A01K1/031 ,  A01K61/00 ,  A61D3/00 ,  G03H1/0443 ,  A61B2503/40

Abstract: Provided is a method of monitoring a heart rate of an open circulatory system aquatic organism including water fleas, zebrafish, brine shrimp, and the method of evaluating individual response by real time measurement of a heart rate of an aquatic organism and the individual response evaluation apparatus by real time measurement of a heart rate of an aquatic organism according to the present invention may effectively fix the aquatic organism for real time measurement of the heart rate of an aquatic organism, and may measure the heart rate using digital holography to display the heart rate while configuring a data format to allow the corresponding data to be stored for a long time, thereby treating a compound for inducing an individual response, securing a heart rate change in real time by image processing, and then effectively determining the presence or absence of harmfulness due to induction of the individual response.

公开(公告)号：US12011223B2

公开(公告)日：2024-06-18

申请号：US17280284

申请日：2019-10-08

Applicant: Korea Research Institute of Standards and Science

Inventor： Sang Won Lee ,  Il Doh ,  Hyunji Lee

IPC: A61B3/00 ,  A61B3/10 ,  A61B3/12

CPC classification number: A61B3/0025 ,  A61B3/102 ,  A61B3/1241

Abstract: The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.

公开(公告)号：US20220000356A1

公开(公告)日：2022-01-06

申请号：US17280284

申请日：2019-10-08

Applicant: Korea Research Institute of Standards and Science

Inventor： Sang Won Lee ,  Il Doh ,  Hyunji Lee

IPC: A61B3/00 ,  A61B3/12 ,  A61B3/10

Abstract: The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.