PD-1 peptide inhibitors
    1.
    发明专利

    公开(公告)号:AU2017325866B2

    公开(公告)日:2021-09-09

    申请号:AU2017325866

    申请日:2017-09-15

    Applicant: LEIDOS INC

    Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PDL1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.

    PD-1 PEPTIDE INHIBITORS
    2.
    发明专利

    公开(公告)号:CA3036251A1

    公开(公告)日:2018-03-22

    申请号:CA3036251

    申请日:2017-09-15

    Applicant: LEIDOS INC

    Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PDL1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.

    PD-1 peptide inhibitors
    7.
    发明专利

    公开(公告)号:AU2017325866A1

    公开(公告)日:2019-04-18

    申请号:AU2017325866

    申请日:2017-09-15

    Applicant: LEIDOS INC

    Abstract: This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of PD-1 with its ligand PDL1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.

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