公开(公告)号：WO2021236466A1

公开(公告)日：2021-11-25

申请号：PCT/US2021/032614

申请日：2021-05-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： FOX, Daniel N. ,  FOX, Nathan M. ,  HARRIS, Rodney C.

IPC: G01N15/14

Abstract: Disclosed is a system for use in a flow cytometer for unclogging obstructions in a nozzle from salt crystal formations and clumps of cells or debris. A nozzle system is moved to a docking station so that a nozzle tip is seated in the docking station. Deionized water is pushed through the nozzle in a reverse direction to a waste port so that the nozzle is flushed. The nozzle system can remain in the docked position during nonuse so that salt crystals do not form in or on the nozzle.

公开(公告)号：EP3948223A1

公开(公告)日：2022-02-09

申请号：EP20832026.7

申请日：2020-06-25

Applicant: Life Technologies Corporation

Inventor： GULLEY, Lincoln T. ,  FOX, Daniel N. ,  GOLDFAIN, Angela L.

IPC: G01N15/14

公开(公告)号：EP4474053A2

公开(公告)日：2024-12-11

申请号：EP24195215.9

申请日：2020-06-25

Applicant: Life Technologies Corporation

Inventor： GULLEY, Lincoln T. ,  FOX, Daniel N. ,  GOLDFAIN, Angela L.

IPC: B01L1/02

Abstract: Disclosed is an integrated biocontainment cell sorter that isolates portions of the cell sorter that can create contamination. Two containment systems are utilized. A main cabinet containment system contains input samples. An aerosol management containment area includes a nozzle chamber with a nozzle and a sort chamber with sort plates and collection media that collect a droplet stream from the nozzle. The main cabinet is maintained at a first low pressure and clean air is recirculated under a positive pressure. The aerosol management containment area is kept at a second low pressure, which is lower than the first pressure, so that contamination does not leak from the aerosol management containment area into the main cabinet containment area. A sliding sash window is located over an access opening in the main cabinet and can be moved to access different portions of the main cabinet without changing the substantially constant first low pressure in the main cabinet.

公开(公告)号：EP4474053A3

公开(公告)日：2025-02-19

申请号：EP24195215.9

申请日：2020-06-25

Applicant: Life Technologies Corporation

Inventor： GULLEY, Lincoln T. ,  FOX, Daniel N. ,  GOLDFAIN, Angela L.

IPC: G01N15/14 ,  B01L1/02 ,  G01N35/00

Abstract: Disclosed is an integrated biocontainment cell sorter that isolates portions of the cell sorter that can create contamination. Two containment systems are utilized. A main cabinet containment system contains input samples. An aerosol management containment area includes a nozzle chamber with a nozzle and a sort chamber with sort plates and collection media that collect a droplet stream from the nozzle. The main cabinet is maintained at a first low pressure and clean air is recirculated under a positive pressure. The aerosol management containment area is kept at a second low pressure, which is lower than the first pressure, so that contamination does not leak from the aerosol management containment area into the main cabinet containment area. A sliding sash window is located over an access opening in the main cabinet and can be moved to access different portions of the main cabinet without changing the substantially constant first low pressure in the main cabinet.

公开(公告)号：EP3948224A1

公开(公告)日：2022-02-09

申请号：EP21731631.4

申请日：2021-05-14

Applicant: Life Technologies Corporation

Inventor： FOX, Daniel N. ,  FOX, Nathan M. ,  HARRIS, Rodney C.

IPC: G01N15/14