公开(公告)号：WO2013165588A1

公开(公告)日：2013-11-07

申请号：PCT/US2013/031515

申请日：2013-03-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： MERRIMAN, Barry ,  MOLA, Paul ,  GARDNER, Mark

IPC: C12Q1/68

CPC classification number: C12Q1/6874

Abstract: A method of genotyping includes applying a sample solution including a plurality of copies of a sample polynucleotide to an array of sensors. The sample polynucleotide includes a region associated with an allele. The method further includes measuring using a plurality of sensors of the array of sensors a characteristic of the region of the plurality of copies of the sample polynucleotide and determining using a computational circuitry and the measured characteristics a statistical value indicative of the allele.

Abstract translation: 基因分型的方法包括将包含多个样品多核苷酸拷贝的样品溶液应用于传感器阵列。 样品多核苷酸包括与等位基因相关的区域。 该方法还包括使用传感器阵列的多个传感器测量样品多核苷酸的多个拷贝区域的特征，并使用计算电路和所测量的特征来确定指示等位基因的统计值。