公开(公告)号：WO2015134139A1

公开(公告)日：2015-09-11

申请号：PCT/US2015/014210

申请日：2015-02-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： KADUCHAK, Gregory ,  AKERLUND, Jace ,  MALKIN, Jason ,  WARD, Michael

IPC: G01N15/14

CPC classification number: G01N15/1012 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N2015/1018 ,  G01N2015/1068 ,  G01N2015/1075 ,  G01N2015/1438

Abstract: The present set of embodiments relates to systems and methods for diagnosing a fluidics system and determining data processing settings for a flow cytometer. Systems and methods for diagnosing a fluidics system require accurate measurement and interpretation of fluctuations within the fluid delivery system. Systems and methods for determining data processing settings require an accurate measurement of peak times among various channels and being able to adjust time delay settings wherein peak time is the measurement of time elapsed from the beginning of the data collection time window to the highest peak in the window.

Abstract translation: 本组实施例涉及用于诊断流体系统并确定流式细胞仪的数据处理设置的系统和方法。 用于诊断流体系统的系统和方法需要准确测量和解释流体输送系统内的波动。 用于确定数据处理设置的系统和方法需要精确测量各种通道中的峰值时间，并且能够调整时间延迟设置，其中峰值时间是从数据采集时间窗口开始到数据采集时间窗口的最高峰值的时间的测量 窗口。

公开(公告)号：WO2018005984A1

公开(公告)日：2018-01-04

申请号：PCT/US2017/040322

申请日：2017-06-30

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： WARD, Michael ,  SELBERG, Saul ,  MALKIN, Jason ,  LEFTON, Ken

IPC: G01N15/14 ,  G01N15/10

Abstract: The present disclosure provides devices, systems and methods for concentrating particles after application of a field and flipping the direction of the particles. The field applied to the particles can be an acoustic field. The particles can be flipped from a first flow stream at a higher speed into a second flow stream at a lower speed to aid in concentrating the particles, including concentration within an analysis region.

Abstract translation: 本公开提供了用于在施加场并翻转粒子的方向之后浓缩粒子的装置，系统和方法。 应用于粒子的场可以是声场。 颗粒可以以较高的速度从第一流动物流翻转到较低速度的第二流动物流中以有助于浓缩颗粒，包括浓度在分析区域内。

公开(公告)号：WO2017116651A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/065734

申请日：2016-12-09

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： WARD, Michael ,  MALKIN, Jason

IPC: G01N15/14 ,  F04B11/00 ,  F04B23/04 ,  G05D7/06 ,  F04C28/02

CPC classification number: G01N15/1404 ,  F04B11/00 ,  F04B13/00 ,  F04B23/04 ,  F04B49/065 ,  F04B2205/05 ,  F04B2205/09 ,  F04C2/08 ,  F04C15/0049 ,  F04C28/02 ,  F04C2270/145 ,  F04C2270/185 ,  F04C2270/205 ,  F04C2270/215 ,  F04C2270/44 ,  F04C2270/80 ,  F04C2270/86 ,  F04C2270/90 ,  G01N2015/1409 ,  G05D7/0682

Abstract: An embodiment of a system with a minute measure of pulsatility in a flow of a fluid is described that comprises a first pump configured to flow the fluid to a junction at a first flow rate that comprises a measure of pulsatility; and a second pump configured to flow a portion of the fluid from the junction at a second flow rate that is less than the first flow rate to produce a flow of the fluid at a third flow rate from the junction with a minute measure of pulsatility.

Abstract translation: 描述了在流体流动中具有微小脉动性度量的系统的实施例，其包括第一泵和第二泵，所述第一泵构造成以第一流量使流体流动到接合点，所述第一流量包括 搏动; 以及第二泵，所述第二泵构造成以小于所述第一流速的第二流速使来自所述接合部的所述流体的一部分流动，以从所述接头以第三流速产生具有微小脉动测量的流体流。

公开(公告)号：EP3479097A1

公开(公告)日：2019-05-08

申请号：EP17748584.4

申请日：2017-06-30

Applicant: Life Technologies Corporation

Inventor： WARD, Michael ,  SELBERG, Saul ,  MALKIN, Jason ,  LEFTON, Ken

IPC: G01N15/14 ,  G01N15/10

公开(公告)号：EP3114458A1

公开(公告)日：2017-01-11

申请号：EP15703722.7

申请日：2015-02-03

Applicant: Life Technologies Corporation

Inventor： KADUCHAK, Gregory ,  AKERLUND, Jace ,  MALKIN, Jason ,  WARD, Michael

IPC: G01N15/14

CPC classification number: G01N15/1012 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N2015/1018 ,  G01N2015/1068 ,  G01N2015/1075 ,  G01N2015/1438

Abstract: The present set of embodiments relates to systems and methods for diagnosing a fluidics system and determining data processing settings for a flow cytometer. Systems and methods for diagnosing a fluidics system require accurate measurement and interpretation of fluctuations within the fluid delivery system. Systems and methods for determining data processing settings require an accurate measurement of peak times among various channels and being able to adjust time delay settings wherein peak time is the measurement of time elapsed from the beginning of the data collection time window to the highest peak in the window.

Abstract translation: 本组实施例中涉及的系统和方法用于诊断流体系统和确定性采矿数据处理设置流式细胞仪。 用于诊断流体系统的系统和方法需要精确的测量和所述流体输送系统内的波动的解释。系统和用于确定性挖掘数据处理设置的方法需要对的各通道之间高峰时间精确测量，并能够调整时间延迟设置worin峰值时间 是时间从数据采集时间窗口在窗口中最高峰的开始经过测量。