Abstract:
In part, the invention relates to a probe suitable for use with image data collection system. The probe, in one embodiment, includes an optical transceiver, such as a beam director, and an acoustic transceiver such as an ultrasound transducer. The optical transceiver is in optical communication with an optical fiber in optical communication with a beam director configured to transmit light and receive scattered light from a sample such as a wall of a blood vessel. The acoustic transceiver includes an ultrasound device or subsystem such as a piezoelectric element configured to generate acoustic waves and receive reflected acoustic waves from the sample.
Abstract:
In one aspect, the invention relates to an imaging probe. The imaging probe includes an elongate body having a proximal end and distal end, the elongate body adapted to enclose a portion of a slidable optical fiber, the optical fiber having a longitudinal axis; and a first optical assembly attached to a distal end of the fiber. The first optical assembly includes a beam director adapted to direct light emitted from the fiber to a plane at a predetermined angle to the longitudinal axis, a linear actuator disposed at the proximal portion of the elongated body, the actuator adapted to affect relative linear motion between the elongate body and the optical fiber; and a second optical assembly located at the distal portion of the elongate body and attached thereto, the second optical assembly comprising a reflector in optical communication with the first optical assembly, the reflector adapted to direct the light to a position distal to the elongate body.
Abstract:
In certain embodiments, the invention provides a method of flushing a lumen of interest having a first diameter and a lumen wall. The method can include the steps of selecting a flush solution such that the flush solution lowers a fluid removal rate of a plurality of terminating lumens, the terminating lumens branching from and in fluid communication with the lumen of interest, at least one of the terminating lumens having a second diameter, the second diameter smaller than the first diameter; flushing the lumen with the flush solution; and collecting optical tomography scan data relative to a portion of the lumen wall.
Abstract:
In certain embodiments, the invention provides a method of flushing a lumen of interest having a first diameter and a lumen wall. The method can include the steps of selecting a flush solution such that the flush solution lowers a fluid removal rate of a plurality of terminating lumens, the terminating lumens branching from and in fluid communication with the lumen of interest, at least one of the terminating lumens having a second diameter, the second diameter smaller than the first diameter; flushing the lumen with the flush solution; and collecting optical tomography scan data relative to a portion of the lumen wall.
Abstract:
Un sistema de recopilación de datos de imágenes (12), que comprende: una sonda de recopilación de datos (25), que comprende: una envoltura (31); un hilo de torsión (98); un marcador radiopaco (99) que comprende un primer extremo y un segundo extremo, estando el primer extremo unido al hilo de torsión (98) y el segundo extremo unido a una punta de sonda (33); un cuerpo de sonda (28), comprendiendo el cuerpo de sonda (28) una fibra óptica; comprendiendo la punta de sonda (33) un material de refuerzo (60); un subsistema de recopilación de datos ópticos que comprende un elemento de dirección de haces (50) configurado para dirigir un haz de luz que tiene un eje central óptico, estando soportado el elemento de dirección de haces (50) por el material de refuerzo (60) y estando inclinado para dirigir el haz de luz distalmente en un ángulo que varía de 0 grados a 20 grados con respecto a la normal de un eje longitudinal de la fibra óptica; y un subsistema de recopilación de datos acústicos que tiene un extremo distal y un extremo proximal dispuesto sobre una región del material de refuerzo y soportado por el material de refuerzo (60), comprendiendo el subsistema de recopilación de datos acústicos un transductor ultrasónico (55) configurado para generar una onda acústica que tiene un eje central acústico, estando el transductor (55) inclinado para dirigir la onda acústica distalmente en un ángulo que varía de 5 grados a 15 grados con respecto a la normal de un eje longitudinal de la fibra óptica, donde el elemento de dirección de haces (50) está dispuesto entre el segundo extremo del marcador radiopaco (99) y el extremo proximal del transductor ultrasónico (55) de modo que el elemento de dirección de haces (50) y el transductor ultrasónico (55) están desplazados axialmente de modo que no se superponen entre sí en una dirección axial y de modo que el eje central óptico del haz de luz y el eje del centro acústico de la onda acústica estén separados entre sí en la dirección axial una distancia de entre aproximadamente 300 y aproximadamente 500 micras, donde el elemento de dirección de haces y el transductor ultrasónico están situados de modo que durante velocidades de rotación de sonda que varían de aproximadamente 100 Hz a aproximadamente 200 Hz y velocidades de retroceso de sonda de recopilación de datos que varían de aproximadamente 18 mm/s a aproximadamente 36 mm/s, un período de tiempo entre el momento en que el eje central óptico del haz de luz y el eje central acústico de la onda acústica cruzan un punto de referencia común, varía de aproximadamente M a aproximadamente N; y la punta de sonda (33), el cuerpo de sonda (28), el marcador radiopaco (99) y el hilo de torsión (98) están dispuestos en la envoltura (31), y donde la fibra óptica del cuerpo de sonda (28) está en comunicación óptica con el subsistema de recopilación de datos ópticos.
Abstract:
In certain embodiments, the invention provides a method of flushing a lumen of interest having a first diameter and a lumen wall. The method can include the steps of selecting a flush solution such that the flush solution lowers a fluid removal rate of a plurality of terminating lumens, the terminating lumens branching from and in fluid communication with the lumen of interest, at least one of the terminating lumens having a second diameter, the second diameter smaller than the first diameter; flushing the lumen with the flush solution; and collecting optical tomography scan data relative to a portion of the lumen wall.
Abstract:
In one aspect, the invention relates to one or more rotatable elements and one or more stationary element such that the elements are arranged along a common axis of rotation co- linear with or substantially parallel to an optical path. The optical path is a portion of a sample arm of an interferometer. Further, the rotatable and stationary elements are configured to couple electrical signals and optical signals between a data collection probe and an interface unit or other component of an imaging system. In one embodiment, the data collection probe is a combination ultrasound and OCT probe. In one aspect, the invention relates to a rotary joint in which the optical fiber and a fiber optic rotary joint lie in the center of one or more conductive elements of an electrical rotary joint which are annularly disposed around one or both of the optical fiber and optical rotary joint.
Abstract:
A flush catheter (10) is provided which is configured to be introduced into an orifice to create a flush zone therein. The flush catheter (10) includes a catheter body (11) having an inner cavity (14), the inner cavity being configured to communicate with a source of flush solution, one or more openings (15) configured to expel therethrough flush solution, and a sheath (45) at least partially covering the one or more openings, wherein when flush solution is expelled through the one or more openings, the flush solution is directed by the sheath to flow along an outer surface of the catheter body, (11) thereby creating a flush zone along a length of the outer surface of the catheter body. The flush catheter may be used in combination with an image catheter/probe (36) such as an image catheter/probe utilized in OCT imaging systems.
Abstract:
In certain embodiments, the invention provides a method of flushing a lumen of interest having a first diameter and a lumen wall. The method can include the steps of selecting a flush solution such that the flush solution lowers a fluid removal rate of a plurality of terminating lumens, the terminating lumens branching from and in fluid communication with the lumen of interest, at least one of the terminating lumens having a second diameter, the second diameter smaller than the first diameter; flushing the lumen with the flush solution; and collecting optical tomography scan data relative to a portion of the lumen wall.