公开(公告)号：WO1998010803A1

公开(公告)日：1998-03-19

申请号：PCT/EP1997005038

申请日：1997-09-15

Applicant: LIPOMATRIX INCORPORATED

Inventor： LIPOMATRIX INCORPORATED ,  KNAPP, Terry, R. ,  ANDREWS, Winston, A. ,  COMTE, Pierre

IPC: A61L27/00

CPC classification number: A61F2/12 ,  A61L27/56

Abstract: The invention relates to a tissue implant having visco-elastic characteristics which simulate the natural tissue that is intended to be augmented or replaced. The implant is comprised of a shell or envelope enclosing a compound foam body and a fluid filler material. Both the foam body and the fluid filler should be biocompatible and preferably are substantially radiolucent using standard mammographic materials and protocols. The compound foam body is of elastomeric cellular foam materials. Intercellular communication of the fluid filler provides a hydraulic mechanism for imparting shape and tissue-like consistency to the implant. The compound foam body has multiple regions, each region having a different cellular density, for simulating the tactile characteristics of the natural tissue that the implant is intended to augment or replace. The implant may also have a cavity in the compound foam body configured for providing a hydraulic reservoir for the fluid filler. The resiliency of the compound foam body permits realistic elastic deformation, in response to external pressure, and "rebound" following such deformation.

Abstract translation: 本发明涉及具有粘弹性特性的组织植入物，其模拟旨在增加或替换的天然组织。 植入物由围绕复合泡沫体和流体填充材料的外壳或信封构成。 泡沫体和流体填充物都应该是生物相容性的，并且优选地使用标准乳房X射线照相材料和方案实质上是可透射的。 复合泡沫体是弹性体泡沫材料。 流体填充物的细胞间通信提供了用于赋予植入物形状和组织样稠度的液压机构。 复合泡沫体具有多个区域，每个区域具有不同的细胞密度，用于模拟植入物旨在增加或替代的天然组织的触觉特性。 所述植入物还可以具有在所述复合泡沫体中具有用于为所述流体填充物提供液压储存器的空腔。 复合泡沫体的弹性允许响应于外部压力的现实弹性变形和这种变形之后的“回弹”。