公开(公告)号：WO1997033513A1

公开(公告)日：1997-09-18

申请号：PCT/IB1997000537

申请日：1997-03-11

Applicant: LIPOMATRIX INCORPORATED

Inventor： LIPOMATRIX INCORPORATED ,  KNAPP, Terry ,  KOVACS, Gregory, T., A.

IPC: A61B05/00

CPC classification number: A61B1/00029 ,  A61B1/00016 ,  A61B1/041 ,  A61B1/0653 ,  A61B1/0684 ,  A61B5/0031 ,  A61B5/413 ,  A61B2560/0214 ,  A61B2560/0219 ,  A61B2562/08 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/0291 ,  G06F19/00

Abstract: A biosensing transponder for implantation in an organism including a human comprises a biosensor for sensing one or more physical properties related to the organism after the device has been implanted, including optical, mechanical, chemical, and electrochemical properties, and a transponder for wirelessly transmitting data corresponding to the sensed parameter value to a remote reader. Disclosed embodiments utilize temperature sensors, strain sensors, pressure sensors, magnetic sensors, acceleration sensors, ionizing radiation sensors, acoustic wave sensors, chemical sensors including direct chemical sensors and dye based chemical sensors, and photosensors including imagers and integrated spectrophotometers. The transponder includes an energy coupler for wirelessly energizing the device with a remote energy source, and a control circuit for controlling and accessing the biosensor and for storing identifying data. The energy coupler can be an inductive circuit for coupling electromagnetic energy, a photoelectric transducer for coupling optical energy, or a piezoelectric transducer for coupling ultrasonic energy. The control circuit can be configured to delay, either randomly or by a fixed period of time, transmission of data indicative of the sensed parameter value to thereby prevent a data collision with an adjacent like device. Methods for using an implantable biosensing transponder include the steps of associating the device with an implant, including temporary implants, prostheses, and living tissue implants, physically attaching the device to a flexible catheter, sensing parameter values in an organism, and transmitting data corresponding to the sensed parameter values to a remote reader.

Abstract translation: 用于植入包括人的生物体的生物传感应答器包括用于感测在器件植入之后与生物相关的一种或多种物理性质的生物传感器，包括光学，机械，化学和电化学性质，以及用于无线传输数据的应答器 对应于感测到的远程读取器的参数值。 公开的实施例使用温度传感器，应变传感器，压力传感器，磁传感器，加速度传感器，电离辐射传感器，声波传感器，包括直接化学传感器和基于染料的化学传感器的化学传感器，以及包括成像器和集成分光光度计的光电传感器。 应答器包括能量耦合器，用于利用远程能量源无线地激励装置，以及用于控制和访问生物传感器并用于存储识别数据的控制电路。 能量耦合器可以是用于耦合电磁能的感应电路，用于耦合光能的光电传感器，或用于耦合超声波能量的压电传感器。 控制电路可以被配置为随机地或者在固定的时间段内延迟指示所感测的参数值的数据的传输，从而防止与相邻的类似设备的数据冲突。 使用植入式生物传感应答器的方法包括以下步骤：将装置与植入物相关联，包括临时植入物，假体和活组织植入物，将装置物理地附接到柔性导管，感测生物体中的参数值，以及发送对应于 感测到的参数值给远程读取器。

公开(公告)号：EP0888079A1

公开(公告)日：1999-01-07

申请号：EP97919601.0

申请日：1997-03-11

Applicant: LIPOMATRIX INCORPORATED

Inventor： KNAPP, Terry ,  KOVACS, Gregory, T., A.

IPC: A61B5 ,  G01J3

CPC classification number: A61B1/00029 ,  A61B1/00016 ,  A61B1/041 ,  A61B1/0653 ,  A61B1/0684 ,  A61B5/0031 ,  A61B5/413 ,  A61B2560/0214 ,  A61B2560/0219 ,  A61B2562/08 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/0291 ,  G06F19/00

Abstract: A biosensing transponder for implantation in an organism including a human comprises a biosensor for sensing one or more physical properties related to the organism after the device has been implanted, including optical, mechanical, chemical, and electrochemical properties, and a transponder for wirelessly transmitting data corresponding to the sensed parameter value to a remote reader. Disclosed embodiments utilize temperature sensors, strain sensors, pressure sensors, magnetic sensors, acceleration sensors, ionizing radiation sensors, acoustic wave sensors, chemical sensors including direct chemical sensors and dye based chemical sensors, and photosensors including imagers and integrated spectrophotometers. The transponder includes an energy coupler for wirelessly energizing the device with a remote energy source, and a control circuit for controlling and accessing the biosensor and for storing identifying data. The energy coupler can be an inductive circuit for coupling electromagnetic energy, a photoelectric transducer for coupling optical energy, or a piezoelectric transducer for coupling ultrasonic energy. The control circuit can be configured to delay, either randomly or by a fixed period of time, transmission of data indicative of the sensed parameter value to thereby prevent a data collision with an adjacent like device. Methods for using an implantable biosensing transponder include the steps of associating the device with an implant, including temporary implants, prostheses, and living tissue implants, physically attaching the device to a flexible catheter, sensing parameter values in an organism, and transmitting data corresponding to the sensed parameter values to a remote reader.

Abstract translation: 用于植入包括人类的生物体中的生物传感应答器包括生物传感器和用于无线传输数据的应答器，所述生物传感器用于在植入装置之后感测与生物体有关的一个或多个物理性质，包括光学，机械，化学和电化学特性 对应于到远程阅读器的感测参数值。 所公开的实施例利用温度传感器，应变传感器，压力传感器，磁性传感器，加速度传感器，电离辐射传感器，声波传感器，包括直接化学传感器和染料基化学传感器的化学传感器，以及包括成像器和集成分光光度计的光电传感器。 应答器包括用于利用远程能量源对设备进行无线激励的能量耦合器以及用于控制和访问生物传感器并用于存储识别数据的控制电路。 能量耦合器可以是用于耦合电磁能量的电感电路，用于耦合光能量的光电换能器或用于耦合超声能量的压电换能器。 控制电路可以被配置为随机地或通过固定的时间段来延迟表示所感测的参数值的数据的传输，从而防止与相邻的类似设备的数据冲突。 使用植入式生物传感应答器的方法包括将装置与植入物相关联的步骤，所述植入物包括临时植入物，假体和活组织植入物，物理地将所述装置附接到柔性导管，感测生物体中的参数值， 将感测到的参数值发送给远程读取器。