公开(公告)号：WO9962399A9

公开(公告)日：2000-05-04

申请号：PCT/US9911818

申请日：1999-05-27

Applicant: MASIMO CORP

Inventor： AL-ALI AMMAR ,  DIAB MOHAMED K ,  KIANI MASSI E ,  KOPOTIC ROBERT J ,  TOBLER DAVID R

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/024 ,  A61B5/1455 ,  A61M16/00

CPC classification number: A61B5/14551 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/1459 ,  A61B5/6814 ,  A61B5/6815 ,  A61B5/6819 ,  A61B5/6825 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/742 ,  A61B5/746 ,  A61M16/00 ,  A61M16/021 ,  A61M2230/205

Abstract: An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple sites. In particular, this multiple-site, multiple-parameter pulse oximeter, or "stereo pulse oximeter" (100) simultaneously measures both arterial (SPA02) and venous (SPV02) oxygen saturation at any specific site and generates a corresponding plethysmograph waveform. A corresponding computation of arterial minus venous oxygen saturation is particularly advantageous for oxygen therapy management. An active pulse-inducing mechanism having a scattering-limited drive generates a consistent pulsatile venous signal utilized for the venous blood measurements. The stereo pulse oximeter also measures arterial oxygen saturation and plethysmograph shape parameters across multiple sites. A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistant pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aortic coarctation.

Abstract translation: 改进的脉搏血氧饱和度计在单个和多个位置提供同时，无创的氧状态和光谱体积描记测量。 特别地，这种多位置多参数脉搏血氧计或“立体声脉搏血氧计”（100）同时测量任何特定部位的动脉（SPA02）和静脉（SPV02）氧饱和度，并产生相应的体积描记图波形。 动脉负静脉血氧饱和度的相应计算对于氧疗治疗特别有利。 具有散射限制驱动的主动脉冲诱导机构产生用于静脉血液测量的一致的脉动静脉信号。 立体声脉搏血氧饱和度计还可测量多个部位的动脉血氧饱和度和体积描记图形状参数。 对于新生儿（PPHN），动脉导管未闭（PDA）和主动脉缩窄的持续性肺动脉高压的检测和管理，多个位点之间相应的三角动脉饱和度计算和体积描记图形状参数的比较特别有利。

公开(公告)号：WO0002483A3

公开(公告)日：2000-04-13

申请号：PCT/US9915420

申请日：1999-07-09

Applicant: MASIMO CORP

Inventor： TOBLER DAVID R ,  DIAB MOHAMED K ,  KOPOTIC ROBERT J

IPC: A61B5/00

CPC classification number: A61B5/14542 ,  A61B5/1464 ,  A61B5/6839 ,  A61B5/6882 ,  A61B2503/02

Abstract: A sensor provides pulse oximetry measurements from the presenting portion of a fetus. In particular, a spiral probe is designed to attach the sensor to the fetal scalp. In one sensor configuration, a light emitting region of the probe embedded in the scalp in conjunction with a light detector located at the scalp surface measures absorption from a larger volume of the scalp tissue than conventional fetal sensors. In another sensor configuration, light emitting and light collecting regions of the probe embedded in the scalp are angled with respect to the scalp surface to measure absorption from a larger volume and deeper layers of the scalp tissue than conventional fetal sensors. These sensors increase the likelihood of measuring blood volume changes occurring in larger arterioles versus smaller arterioles or capillaries, yielding a representative measurement of central arterial oxygen saturation. These sensors also reduce the calibration errors caused by a low blood fraction. Localized arteriolar flow is stimulated with heat or vasodilating substances to reduce the effects of localized oxygen consumption and to increase blood fraction. A three-wavelength sensor is utilized to detect a low blood fraction condition.

Abstract translation: 传感器提供来自胎儿呈现部分的脉搏血氧测量。 特别是，螺旋探头设计用于将传感器连接到胎儿头皮上。 在一种传感器配置中，与位于头皮表面处的光检测器一起嵌入头皮中的探头的发光区域测量比传统胎儿传感器更大量的头皮组织的吸收。 在另一种传感器配置中，埋入头皮中的探针的光发射和光收集区域相对于头皮表面成角度，以测量头皮组织比常规胎儿传感器的更大体积和更深层的吸收。 这些传感器增加了测量较大的小动脉相对于较小的小动脉或毛细血管发生的血容量变化的可能性，产生中央动脉血氧饱和度的代表性测量值。 这些传感器还可以减少由低血量导致的校准误差。 局部小动脉血流受热或血管舒张物质刺激，以减少局部氧消耗和增加血液分数的影响。 三波长传感器被用于检测低血液分数状况。

公开(公告)号：CA2333062A1

公开(公告)日：1999-12-09

申请号：CA2333062

申请日：1999-05-27

Applicant: MASIMO CORP

Inventor： AL-ALI AMMAR ,  TOBLER DAVID R ,  KIANI MASSI E ,  DIAB MOHAMED K ,  KOPOTIC ROBERT J

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/024 ,  A61B5/1455 ,  A61M16/00

Abstract: An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple site s. In particular, this multiple-site, multiple-parameter pulse oximeter, or "stereo pulse oximeter" (100) simultaneously measures both arterial (SPA02) and venous (SPV02) oxygen saturation at any specific site and generates a corresponding plethysmograph waveform. A corresponding computation of arteri al minus venous oxygen saturation is particularly advantageous for oxygen thera py management. An active pulse-inducing mechanism having a scattering-limited drive generates a consistent pulsatile venous signal utilized for the venous blood measurements. The stereo pulse oximeter also measures arterial oxygen saturation and plethysmograph shape parameters across multiple sites. A corresponding calculation of delta arterial saturation and comparison of plethysmograph shape parameters between multiple sites is particularly advantageous for the detection and management of persistant pulmonary hypertension in neonates (PPHN), a patent ductus arteriosis (PDA), and aorti c coarctation.

公开(公告)号：AU4214199A

公开(公告)日：1999-12-20

申请号：AU4214199

申请日：1999-05-27

Applicant: MASIMO CORP

Inventor： AL-ALI AMMAR ,  DIAB MOHAMED K ,  KIANI MASSI E ,  KOPOTIC ROBERT J ,  TOBLER DAVID R

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/024 ,  A61B5/1455 ,  A61M16/00