公开(公告)号：WO1997007955A1

公开(公告)日：1997-03-06

申请号：PCT/US1996012756

申请日：1996-08-21

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  LAWECKI, Mark ,  GELBLUM, Eugene, A. ,  ROBINSON, Michelle ,  WOLSTENHOLME, Ralph ,  WOLSTENHOLME, Eugene, B.

IPC: B29C45/17

CPC classification number: B65B3/006 ,  B29C45/0084 ,  B29C45/1701 ,  Y10S425/815

Abstract: An apparatus and method are provided for manufacturing articles, such as syringe barrels (126), substantially free from contaminants. The apparatus is an enclosure (10) defining at least a class 100 and MCB-3 environment, and includes a molding isolation module (12) and a packaging isolation module (14). Any contaminants that may exist within the enclosure (10) are removed by the use of horizontal and vertical laminar airflows directed by air filter units (50). Further, the molding temperature may be selected such that it renders the fabricated articles substantially free from contaminants. The molding isolation module (12) and packaging isolation module (14) keep the fabricated articles substantially free from contaminants from the time the articles are molded to the time the articles are placed in sealed containers (128a, 130, 132, 134) for shipment.

Abstract translation: 提供了一种用于制造基本上没有污染物的制品例如注射器筒（126）的装置和方法。 该设备是限定至少100级和MCB-3环境的外壳（10），并且包括模制隔离模块（12）和封装隔离模块（14）。 可以通过使用由空气过滤器单元（50）引导的水平和垂直层流气流来移除可能存在于外壳（10）内的任何污染物。 此外，可以选择成型温度，使得其使制造的制品基本上不含污染物。 成型隔离模块（12）和包装隔离模块（14）在物品被放置在密封容器（128a，130,132,134）中以便装运时保持制造物品基本上不受污染物的污染 。

公开(公告)号：WO1994022520A1

公开(公告)日：1994-10-13

申请号：PCT/US1994003618

申请日：1994-04-01

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  TROMBLEY, Frederick, W., III ,  DEDOLA, Salvatore, J.

IPC: A61M25/00

CPC classification number: A61M39/10 ,  A61M2039/1033 ,  A61M2039/1044 ,  Y10S604/905

Abstract: A luer connector (10) is provided with a tactile and audible torque indicator. The indicator comprises a detent incorporated between the female cylindrical component (14) of the luer connector and a rotatable collar (32) mounted thereon. As the collar (32) is turned in a clockwise direction, the collar is impeded by the detent formed by opposingly projecting protuberances (34, 38) between the inside of the collar and the outside of the female cylindrical luer component (14). As the threaded luer connection is tightened, requiring additional torque to tighten it further, the additional torque overcomes the resistance of the detent, allowing the collar protuberance to slip past the cylinder protuberance. The female luer component may also be provided with a color patch or pattern (40), to indicate by its rotation, when the detent has been overcome, that the luer connection has been appropriately tightened.

Abstract translation: 路厄连接器（10）设置有触觉和听觉扭矩指示器。 指示器包括结合在路厄尔连接器的阴圆柱形部件（14）和安装在其上的可旋转轴环（32）之间的制动器。 当套环（32）沿顺时针方向转动时，套环由在套环的内部和阴圆柱形路厄器件（14）的外侧之间相对突出的突起（34,38）形成的制动器阻碍。 当螺纹鲁尔连接被拧紧时，需要额外的扭矩来进一步拧紧，额外的扭矩克服了制动器的阻力，允许轴环凸起滑过气缸凸起。 阴路厄部件还可以设置有色块或图案（40），以通过其旋转来指示当制动器已被克服时，鲁尔连接已被适当地拧紧。

公开(公告)号：WO1994012102A1

公开(公告)日：1994-06-09

申请号：PCT/US1993011383

申请日：1993-11-23

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  RHINEHART, Edward, J. ,  SPOHN, Michael, A.

IPC: A61B05/055

CPC classification number: G01R33/34084 ,  A61B2017/00557 ,  A61B2090/374

Abstract: An insertable intracavity probe (10) for use in magnetic resonance imaging of an area of interest in a relatively inaccessible region of the body is disclosed. The probe has an internal pickup coil (18) carried at the distal end of a shaft (12) for rectal insertion of the coil and an inflatable anti-migration cuff (72) to hold the probe in position and prevent outward migration thereof during a procedure. The anti-migration cuff (72) is carried on an outer sleeve (16) which is slidably and rotatably mounted on the shaft. The coil (18) is carried on a resilient tip structure (38) at the distal end of the shaft which is flexible in the plane normal to the plane of the coil. Deflection of the coil assembly is controlled by a pair of control lines (46 and 48) attached to the distal end of the tip structure. The lines may be selectively tensioned to deflect the coil in the direction of tension by a thumb wheel control (56) at the handle (26) of the probe.

Abstract translation: 公开了一种可插入腔内探针（10），用于在身体相对不可接近的区域中的感兴趣区域的磁共振成像。 该探头具有一个内部拾取线圈（18），该拾取线圈（18）承载在用于直线插入线圈的轴（12）的远端，以及一个可充气的反向移动箍（72），用于将探针保持在适当的位置，并防止在 程序。 反移动袖带（72）承载在可滑动地并可旋转地安装在轴上的外套筒（16）上。 线圈（18）承载在轴的远端处的弹性尖端结构（38）上，该顶端结构在垂直于线圈平面的平面中是柔性的。 线圈组件的偏转由附接到尖端结构的远端的一对控制线（46和48）控制。 可以选择性地张紧线以通过在探针的手柄（26）处的拇指轮控制（56）沿着张力方向偏转线圈。

公开(公告)号：WO1993005706A1

公开(公告)日：1993-04-01

申请号：PCT/US1992007891

申请日：1992-09-17

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  KRESSEL, Herbert, Y. ,  RHINEHART, Edward, J. ,  SCHNALL, Mitchell ,  LENKINSKI, Robert, E. ,  IMAI, Yutaka

IPC: A61B05/055

CPC classification number: G01R33/341 ,  A61B5/055 ,  A61B5/4255 ,  A61M25/1011 ,  G01R33/285 ,  G01R33/34084

Abstract: An insertable intracavity probe (10) for use in magnetic resonance imaging of an area of interest in a body cavity particularly the colon, has an elongate shaft with a handle (18) at its proximal end and an inflatable balloon structure (16) at its distal end. The balloon structure has an outer balloon (26) containing a loop-type pickup coil (20) for connection to an interfacing network (12). The coil is sandwiched between two internal separately inflatable balloons (22 and 24), and when the probe is inserted, the coil can be optimally positioned relative to the area of interest by controlled differential inflation of the balloons. The probe also has an insertable rod-like mandrel (56) for providing twisting orbital-type movement of the balloon structure on the shaft, by rotation of the mandrel, useful to steer the probe along curves or bends in the body cavity when it is being inserted. In a modified form of the probe, the mandrel can be used to rotate the coil and the internal balloons as a unit within the outer balloon for optimal in situ angular positioning of the coil.

公开(公告)号：WO1987003107A1

公开(公告)日：1987-05-21

申请号：PCT/US1986002432

申请日：1986-11-14

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  JOHANSSON, Leif, A. ,  HELLMICK, Mark ,  WEBER, Otto

IPC: G03B42/02

CPC classification number: G03B42/045

Abstract: A film feeding mechanism for use during medical x-ray techniques, particularly angiography. Sheets of film (46) are fed sequentially at high speed into a film exposure device (34), in a manner so as to reduce damage to the films, including the build-up and discharge of static charge on the films. In the film exposure device (34), a free-floating lower clamping assembly (144) clamps each film (46) from the center of the film progressively outward towards its leading and trailing ends, to eliminate wrinkling of the film.

Abstract translation: 一种用于医疗x射线技术，特别是血管造影术的胶片输送机构。 膜（46）的片材以高速顺序进料到膜曝光装置（34）中，以便减少对膜的损伤，包括膜上静电荷的积聚和放电。 在薄膜曝光装置（34）中，自由浮动的下夹紧组件（144）将每个薄膜（46）从薄膜的中心逐渐向外朝向其前端和后端夹紧，以消除薄膜的起皱。

公开(公告)号：WO1998017336A1

公开(公告)日：1998-04-30

申请号：PCT/US1997017840

申请日：1997-10-01

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  HIRSCHMAN, Alan, D. ,  REILLY, David, M.

IPC: A61M05/145

CPC classification number: A61M5/14546 ,  A61M5/1456 ,  A61M5/1458 ,  A61M5/31511 ,  A61M2005/14573

Abstract: The present invention provides a syringe and a powered injector for use therewith in which the syringe is attachable to a powered drive member of an injector over a range of relative axial positions of the syringe plunger and the drive member. The syringe comprises a plunger, and a plunger extension connected thereto and extending rearward from the plunger, such that the syringe may be operated manually or by a powered injector. By providing a plurality of cooperating attachment members over a range of axial positions on at least one of the plunger extension or the powered drive member, operative attachment of the plunger and the drive member is made possible at multiple axial positions of the plunger (within the syringe) for each axial position of the drive member over at least a range of possible plunger axial positions. Attachment of the plunger to the drive member at various axial positions of the plunger thus becomes an easier task than previously possible with current powered injector systems.

Abstract translation: 本发明提供了一种注射器和用于其的动力注射器，其中注射器可在注射器柱塞和驱动构件的相对轴向位置的范围内附接到注射器的动力驱动构件。 注射器包括柱塞和连接到其上并从柱塞向后延伸的柱塞延伸部，使得注射器可以手动操作或通过动力注射器操作。 通过在柱塞延伸部或动力驱动部件中的至少一个上的一定范围的轴向位置设置多个配合的附接部件，可以在柱塞的多个轴向位置 注射器），用于驱动构件的每个轴向位置在可能的柱塞轴向位置的至少一个范围上。 因此，柱塞在柱塞的各个轴向位置处附接到驱动构件成为比以前可能的当前动力喷射器系统更容易的任务。

公开(公告)号：WO1997045150A1

公开(公告)日：1997-12-04

申请号：PCT/US1997007923

申请日：1997-05-09

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  UBER, Arthur, E., III ,  HAVRILLA, Joseph, B. ,  HIRSCHMAN, Alan, D.

IPC: A61M05/142

CPC classification number: A61M5/16827 ,  A61M5/007 ,  A61M5/142 ,  A61M5/16886 ,  A61M5/172 ,  A61M2205/12

Abstract: The present invention provides a number of pumping systems and injection systems particularly useful for injecting a liquid medium into a patient. In general, the pumping systems comprise a removable pumping unit. The removable pumping unit includes means for pressurizing the liquid medium via the rotational displacement of the liquid medium. The present invention also provides a pumping system comprising a pumping unit for pressurizing the liquid medium and a feedback-controlled drive means in connection with the pumping unit for providing a controlled powered drive to the pumping unit. The pumping system further comprises a flow meter for measuring the flow rate of the pressurized liquid medium exiting the pumping system and control means in communicative connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit. The control means is suitable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit. The control signal provided to the drive means is a function of the feedback signal.

Abstract translation: 本发明提供了一些特别可用于将液体介质注射到患者体内的泵送系统和注射系统。 通常，泵送系统包括可拆卸的泵送单元。 可移除泵送单元包括用于通过液体介质的旋转位移对液体介质进行加压的装置。 本发明还提供了一种泵送系统，其包括用于对液体介质进行加压的泵送单元和与泵送单元结合的反馈控制的驱动装置，用于向泵送单元提供受控的动力驱动。 泵送系统还包括用于测量离开泵送系统的加压液体介质的流量的流量计和与驱动装置通信连接的控制装置，用于提供控制信号以控制提供给泵送单元的动力驱动。 控制装置适于从流量计接收对应于离开泵送单元的加压液体介质的流量的反馈信号。 提供给驱动装置的控制信号是反馈信号的函数。

公开(公告)号：WO1995011722A1

公开(公告)日：1995-05-04

申请号：PCT/US1994012229

申请日：1994-10-27

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  HEILMAN, Marlin, S. ,  UBER, Arthur, E., III

IPC: A61M31/00

CPC classification number: A61M5/142 ,  A61M5/007 ,  A61M5/16827 ,  A61M5/16886 ,  A61M5/172 ,  A61M2205/12

Abstract: This invention is an apparatus and process for injection of a multiple number of patients with a sterile fluid while assuring sterility by providing means which control the fluid flow (35) in such ways that injection means (31) are isolated from each other, as well as from the source of sterile fluid, such as by use of selective valving means and disposable dosing units.

Abstract translation: 本发明是一种用于通过提供以注射装置（31）彼此分离的方式控制流体流动（35）的装置来同时确保无菌的同时注射多个患有无菌流体的患者的装置和方法，以及 如来自无菌流体的源，例如通过使用选择性阀装置和一次性给药单元。

公开(公告)号：WO1998020920A3

公开(公告)日：1998-05-22

申请号：PCT/US1997020122

申请日：1997-11-04

Applicant: MEDRAD, INC.

Inventor： MEDRAD, INC. ,  HITCHINS, Mark, W. ,  RHINEHART, Edward, J. ,  REILLY, David, M. ,  MCCOPPIN, Anthony, S. ,  DUFALLA, Thomas, L. ,  MASARIK, Robert, J.

IPC: A61M05/145

公开(公告)号：WO1997036635A1

公开(公告)日：1997-10-09

申请号：PCT/US1997005014

申请日：1997-03-27

Applicant: MEDRAD, INC. ,  SPOHN, Michael, A. ,  ASHCRAFT, Robert, J., Jr. ,  BOWSER, Craig, John ,  PAVLIK, P., Eric ,  YARZEBINSKI, Albert, John

Inventor： MEDRAD, INC.

IPC: A61M37/00

CPC classification number: A61M5/14546 ,  A61M5/14566

Abstract: The present syringe adapter (100), which permits use of syringes (40) of various types, sizes and configurations to be used with a front-loading injector (10), includes a removable injector face plate (120) having a releasable mounting mechanism (122a, 122b) for attaching the adapter face plate (120) to a front-load injector (10), a reducing sleeve (140) having a recess (190) for receiving the distal flange (44) of syringe (40), locking pivot arms (220, 240) pivotly attached to the reducing sleeve (140) to releasably engage syringe flange (44), and a piston extension (320) provided for extending the injector drive piston (16) for engagement with syringe plunger (46).

Abstract translation: 本注射器适配器（100），其允许使用与前装载注射器（10）一起使用的各种类型，尺寸和构型的注射器（40），其包括具有可释放的安装机构的可移除的注射器面板（120） （122a），用于将适配器面板（120）附接到前负载喷射器（10）;还原套筒（140）具有用于接收注射器（40）的远端凸缘（44）的凹部（190） 枢转地附接到所述还原套筒（140）以可释放地接合注射器凸缘（44）的枢转臂（220,240）和设置用于延伸所述注射器驱动活塞（16）以与注射器柱塞（46）接合的活塞延伸部 ）。