公开(公告)号：SG10202001388YA

公开(公告)日：2020-04-29

申请号：SG10202001388Y

申请日：2016-08-17

Applicant: ACADEMIA SINICA ,  MEMORIAL SLOAN KETTERING CANCER CENTER

Inventor： MOORE MALCOLM ,  SHIEH JAE-HUNG ,  SU TSANN-LONG ,  LEE TE-CHANG

Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of small lung cell carcinoma (SCLC).

公开(公告)号：CA2994009A1

公开(公告)日：2017-02-23

申请号：CA2994009

申请日：2016-08-17

Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER ,  ACADEMIA SINICA

Inventor： MOORE MALCOLM ,  SHIEH JAE HUNG ,  SU TSANN LONG ,  LEE TE CHANG

IPC: C07C275/42 ,  A61P35/02 ,  C07D215/42 ,  C07D219/08

Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of a cancer, selected from the group consisting of various types of human leukemia [such as acute myeloid leukemia (ALL) and acute B Lymphoblastic leukemia (B-ALL)], lymphomas, small lung cell carcinoma (SCLC), sarcomas, and others.

公开(公告)号：AU2016308116A1

公开(公告)日：2018-02-15

申请号：AU2016308116

申请日：2016-08-17

Applicant: ACADEMIA SINICA ,  MEMORIAL SLOAN KETTERING CANCER CENTER

Inventor： MOORE MALCOLM ,  SHIEH JAE HUNG ,  SU TSANN LONG ,  LEE TE CHANG

IPC: C07C275/42 ,  A61P35/02 ,  C07D215/42 ,  C07D219/08

Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of a cancer, selected from the group consisting of various types of human leukemia [such as acute myeloid leukemia (ALL) and acute B Lymphoblastic leukemia (B-ALL)], lymphomas, small lung cell carcinoma (SCLC), sarcomas, and others.

公开(公告)号：KR20180052617A

公开(公告)日：2018-05-18

申请号：KR20187005781

申请日：2016-08-17

Applicant: ACAD SINICA ,  MEMORIAL SLOAN KETTERING CANCER CENTER

Inventor： MOORE MALCOLM ,  SHIEH JAE HUNG ,  SU TSANN LONG ,  LEE TE CHANG

IPC: A61K31/17 ,  A61K45/06 ,  A61P35/02

CPC classification number: A61K31/17 ,  A61K45/06

Abstract: 다양한유형의인간백혈병[급성골수성백혈병(ALL) 및급성 B 림프구성백혈병(B-ALL)과같은], 림프종, 소폐세포암(SCLC), 육종등으로이루어진군으로부터선택되는, 암의치료에서, 수용성 NDA 가교제인, 우레이도무스틴(BO-1055)을사용하는방법.

公开(公告)号：AU2012335668A1

公开(公告)日：2014-07-03

申请号：AU2012335668

申请日：2012-11-09

Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER

Inventor： MOORE MALCOLM ,  ERTEM SERVER A

IPC: C07D213/87 ,  A61K31/166 ,  A61K31/341 ,  A61K31/415 ,  A61K31/44 ,  A61P35/00

Abstract: Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a benzylidinebenzohydrazide of formula: formula (I), wherein X is carbon or nitrogen.

公开(公告)号：AU2012335665A1

公开(公告)日：2014-07-03

申请号：AU2012335665

申请日：2012-11-09

Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER

Inventor： MOORE MALCOLM ,  ERTEM SERVER A

IPC: C07D311/92 ,  A61K31/352 ,  A61P35/00

Abstract: Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a 2-amino-4H-naphtho[1,2-b]pyran-3-carbonitrile of formula. (I). wherein Y is CR