Polymer coatings containing drug powder of controlled morphology

    公开(公告)号:AU2011232760A1

    公开(公告)日:2011-10-27

    申请号:AU2011232760

    申请日:2011-10-05

    Abstract: C:NRPobWCC\SXD\3914539_ .DOC-5/10/201I A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical 5 agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do I0 not substantially modify the morphology of said pharmaceutical agent.

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