公开(公告)号：DE602005013253D1

公开(公告)日：2009-04-23

申请号：DE602005013253

申请日：2005-09-01

Applicant: MICROCHIPS INC

Inventor： SANTINI JOHN T ,  SBIAA ZOUHAIR ,  COPPETA JONATHAN R ,  UHLAND SCOTT ,  SHEPPARD NORMAN F JR

IPC: B01L3/00 ,  A61K9/00 ,  A61M37/00

Abstract: Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.

公开(公告)号：CA2577709A1

公开(公告)日：2006-03-09

申请号：CA2577709

申请日：2005-09-01

Applicant: MICROCHIPS INC

Inventor： SBIAA ZOUHAIR ,  COPPETA JONATHAN R ,  SANTINI JOHN T JR ,  SHEPPARD NORMAN F JR ,  UHLAND SCOTT

IPC: B01L3/00 ,  A61K9/00 ,  A61M37/00

Abstract: Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.

公开(公告)号：AU2005279729A1

公开(公告)日：2006-03-09

申请号：AU2005279729

申请日：2005-09-01

Applicant: MICROCHIPS INC

Inventor： SANTINI JOHN T JR ,  UHLAND SCOTT ,  SBIAA ZOUHAIR ,  COPPETA JONATHAN R

IPC: B01L3/00 ,  A61K9/00 ,  A61M37/00

Abstract: Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.

公开(公告)号：AT505224T

公开(公告)日：2011-04-15

申请号：AT03815904

申请日：2003-08-15

Applicant: MICROCHIPS INC

Inventor： UHLAND SCOTT ,  POLITO BENJAMIN ,  MALONEY JOHN ,  SHEPPARD NORMAN ,  HERMAN STEPHEN ,  YOMTOV BARRY

IPC: A61M5/14 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/042 ,  A61K9/00 ,  A61M5/142 ,  A61M37/00 ,  A61N1/32

Abstract: Devices and methods are provided for the controlled release or exposure of reservoir contents. The device includes a substrate, a plurality of reservoirs in the substrate, reservoir contents disposed in the reservoirs, discrete reservoir caps covering each reservoir to seal the reservoir contents in the reservoirs, and control circuitry for selectively disintegrating the reservoir caps to release or expose the reservoir contents in vivo. At least one of the reservoir caps comprises a first electrically conductive layer coated with one or more protective layers. In one embodiment, the control circuitry comprises an electrical input lead and an electrical output lead connected to and directly contacting each of said reservoir caps and a source of electric power for applying an electrical current through each reservoir cap in an amount effective to rupture each of the reservoir caps.

公开(公告)号：AT424928T

公开(公告)日：2009-03-15

申请号：AT05805709

申请日：2005-09-01

Applicant: MICROCHIPS INC

Inventor： SANTINI JOHN ,  SBIAA ZOUHAIR ,  COPPETA JONATHAN ,  UHLAND SCOTT ,  SHEPPARD NORMAN F JR

IPC: B01L3/00 ,  A61K9/00 ,  A61M37/00

Abstract: Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.

公开(公告)号：AU2005279729B2

公开(公告)日：2010-12-02

申请号：AU2005279729

申请日：2005-09-01

Applicant: MICROCHIPS INC

Inventor： SANTINI JOHN T JR ,  UHLAND SCOTT ,  SBIAA ZOUHAIR ,  SHEPPARD NORMAN F JR ,  COPPETA JONATHAN R

IPC: B01L3/00 ,  A61K9/00 ,  A61M37/00

Abstract: Devices, such as medical devices, are provided which include a body portion having at least one reservoir which has two or more openings, the two or more openings being defined in part by a reservoir cap support; reservoir contents, such as a drug formulation or sensor, disposed inside the reservoir; and a reservoir cap which closes off the two or more reservoir openings. The reservoir cap, which can be ruptured, controls release or exposure of the reservoir contents. In one embodiment, the device is an implantable medical device and provides for the controlled release of drug or exposure of a sensor.