公开(公告)号：CA1253507A

公开(公告)日：1989-05-02

申请号：CA494544

申请日：1985-11-04

Applicant: MITSUI TOATSU CHEMICALS

Inventor： UENO TOMOYUKI ,  HONDA TADATOSHI ,  JIMBO TAKASHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J23/90 ,  C07D209/08

Abstract: In a process for preparing an indole by reacting an aniline with a diol, a catalyst the activity of which has been reduced through its use in the reaction is brought into contact with an inert gas containing 5 vol.% or less of oxygen so that the catalyst is regenerated for its repeated utilization. The activity of the regenerated catalyst is enhanced further when it is subjected to a reducing treatment for actuation upon its reutilization.

公开(公告)号：CA1194492A

公开(公告)日：1985-10-01

申请号：CA432038

申请日：1983-07-07

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIHIDE ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J21/00 ,  B01J23/00 ,  B01J27/00 ,  C07B61/00 ,  C07D209/08

Abstract: SPECIFICATION Title of the Invention PREPARATION PROCESS FOR INDOLES Disclosed herein is a preparation process for an indole, which process comprises subjecting an N-(.beta.-hydroxy)-alkylaniline, in the presence of a catalyst and at a superatmospheric pressure, to a gas-phase catalytic reaction. The present process improves the selectivity of the reaction and the service life of the catalyst.

公开(公告)号：GB2123820A

公开(公告)日：1984-02-08

申请号：GB8316911

申请日：1983-06-22

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIO ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/08 ,  C07D209/12

Abstract: Indoles are prepared by reacting an aniline and an ethylene glycol in the gas-phase in the presence of a catalyst, the reaction being carried out at superatmospheric pressure, e.g. in the range 1.1 ô 10 to 1.0 ô 10 Pa, and e.g. at a temperature in the range 200 to 600 DEG C. The aniline and glycol can be passed over the catalyst at a molar ratio of 1:0.01 to 5 and at a feed rate of 0.01 to 10 per hour in terms of liquid hourly space velocity. By conducting the reaction at superatmospheric pressure, the selectivity and catalyst life are improved.

公开(公告)号：FR2529202A1

公开(公告)日：1983-12-30

申请号：FR8310514

申请日：1983-06-24

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIO ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/08

Abstract: Disclosed herein is to react an aniline and an ethylene glycol at a superatmospheric pressure in preparing an indole by subjecting the aniline and ethylene glycol to a gas-phase catalytic reaction in the presence of a catalyst, thereby improving the selectivity of the reaction and the service life of the catalyst.

公开(公告)号：DK0427287T3

公开(公告)日：1995-10-02

申请号：DK90121473

申请日：1990-11-09

Applicant: MITSUI TOATSU CHEMICALS

Inventor： HONDA TADATOSHI ,  KOTANI MAKOTO

IPC: C07D209/68 ,  B01J23/50 ,  B01J23/89 ,  C07B61/00 ,  C07D209/04

Abstract: A process is provided for the preparation of an indole from aniline or a derivative thereof and a polyhydric alcohol. The reaction is carried out in the presence of a catalyst composed of a carrier having a specific surface area of at least 10 m /g and silver supported on the carrier. The catalyst also contains as an additional component a specific amount of at least one element selected from Co, Fe and Ni. Deterioration in catalytic performance of the catalyst during the reaction and its regeneration are therefore minimized.

公开(公告)号：CH654572A5

公开(公告)日：1986-02-28

申请号：CH343383

申请日：1983-06-23

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIO ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/08 ,  C07D209/04

公开(公告)号：GB2123822A

公开(公告)日：1984-02-08

申请号：GB8317676

申请日：1983-06-29

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIHIDE ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J21/00 ,  B01J23/00 ,  B01J27/00 ,  C07B61/00 ,  C07D209/08

Abstract: Indoles are prepared by subjecting an N-(???-hydroxy) alkylaniline, in the presence of a catalyst and at a superatmospheric pressure, to a gas-phase catalytic reaction, whereby the selectivity of the reaction and the service life of the catalyst are improved.

公开(公告)号：DE3324092A1

公开(公告)日：1984-01-12

申请号：DE3324092

申请日：1983-07-05

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIHIDE ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J21/00 ,  B01J23/00 ,  B01J27/00 ,  C07B61/00 ,  C07D209/08

Abstract: Disclosed herein is a preparation process for an indole, which process comprises subjecting an N-( beta -hydroxy)-alkylaniline, in the presence of a catalyst and at a super-atmospheric pressure, to a gas-phase catalytic reaction. The present process improves the selectivity of the reaction and the service life of the catalyst.

公开(公告)号：DE3581587D1

公开(公告)日：1991-03-07

申请号：DE3581587

申请日：1985-11-05

Applicant: MITSUI TOATSU CHEMICALS

Inventor： UENO TOMOYUKI ,  HONDA TADATOSHI ,  JIMBO TAKASHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J23/90 ,  C07D209/08 ,  B01J23/94 ,  B01J23/96

Abstract: In a process for preparing an indole by reacting an aniline with a diol, a catalyst the activity of which has been reduced through its use in the reaction is brought into contact with an inert gas containing 5 vol.% or less of oxygen so that the catalyst is regenerated for its repeated utilization. The activity of the regenerated catalyst is enhanced further when it is subjected to a reducing treatment for activation upon its reutilization.

公开(公告)号：CH653674A5

公开(公告)日：1986-01-15

申请号：CH374183

申请日：1983-07-07

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KUDOH AKIHIDE ,  HONDA TADATOSHI ,  KOTANI MAKOTO ,  TERADA KAZUHIRO ,  TSUDA TAKESHI ,  KIYONO SHINJI

IPC: C07D209/04 ,  B01J21/00 ,  B01J23/00 ,  B01J27/00 ,  C07B61/00 ,  C07D209/08