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公开(公告)号:US20190316116A1
公开(公告)日:2019-10-17
申请号:US15535899
申请日:2015-12-15
Applicant: MONASH UNIVERSITY
Inventor: Benjamin POREBSKI , Ashley BUCKLE
Abstract: The invention relates to a highly stable polypeptide scaffold comprising an amino acid sequence based on a fibronectin type III (Fn3) domain and a polypeptide comprising the scaffold with grafted loops. The invention also relates to a nucleic acid molecule encoding the polypeptide scaffold, a method of making the polypeptide scaffold, and a composition comprising the polypeptide scaffold.