MICROFLUIDIC MIXING DEVICE AND METHOD
    3.
    发明申请
    MICROFLUIDIC MIXING DEVICE AND METHOD 审中-公开
    微流体混合装置和方法

    公开(公告)号:WO2017143120A1

    公开(公告)日:2017-08-24

    申请号:PCT/US2017/018268

    申请日:2017-02-17

    CPC classification number: B01F13/0059 B01F11/0071

    Abstract: A microfluidic mixing device comprising two bellows pumps (105, 115), microfluidic cartridges comprising the same and methods for use of the same are provided. The disclosed device enables efficient mixing of samples at the microfluidic scale. More particularly, the microfluidic mixing device comprises: a first bellows pump (105); a second bellows pump (115); a first microchannel fluidly interconnecting the first bellows pump (105) with a sample inlet and a reagent reservoir, wherein the first microchannel comprises a valve (V10) interposed between the pump and the inlet, and a valve (V1) interposed between the pump and the reservoir; a second microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump (115), wherein the second micro channel comprises a valve (V11) interposed between the first and second pump; a third microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump, wherein the third micro channel comprises a valve (V11) interposed between the first and second pump; a first and second pneumatic member pneumatically connected to the first and second bellows pumps; wherein, the volume of the second bellows pump (115) is greater than the volume of the first bellows pump (105).

    Abstract translation: 提供了一种包括两个波纹管泵(105,115)的微流体混合装置,包括其的微流体筒及其使用方法。 所公开的装置能够在微流体规模上有效地混合样品。 更特别地,微流体混合装置包括:第一波纹管泵(105); 第二波纹管泵(115); 将所述第一波纹管泵(105)与样品入口和试剂储存器流体互连的第一微通道,其中所述第一微通道包括介于所述泵和所述入口之间的阀(V10)以及介于所述泵和所述入口之间的阀(V1) 水库; 将所述第一波纹管泵(105)与所述第二波纹管泵(115)流体互连的第二微通道,其中所述第二微通道包括插入在所述第一和第二泵之间的阀(V11) 将所述第一波纹管泵(105)与所述第二波纹管泵流体互连的第三微通道,其中所述第三微通道包括插入在所述第一泵和所述第二泵之间的阀(V11) 气动连接到第一和第二波纹管泵的第一和第二气动元件; 其中第二波纹管泵(115)的容积大于第一波纹管泵(105)的容积。

    SPECIMEN COLLECTION AND DELIVERY APPARATUS
    4.
    发明申请
    SPECIMEN COLLECTION AND DELIVERY APPARATUS 审中-公开
    样本采集和传送设备

    公开(公告)号:WO2016176613A1

    公开(公告)日:2016-11-03

    申请号:PCT/US2016/030194

    申请日:2016-04-29

    Abstract: A specimen collection and delivery apparatus for collecting clinical specimens and delivery of samples thereof to, e.g., microfluidic testing devices for diagnostic analysis is disclosed. The specimen collection and delivery apparatus includes a closure housing for coupling with a sample tube at one end, an open luer for coupling with a complementary luer on a microfluidic device at the other end, and a filter matrix disposed in the interior. The filter matrix is air permeable and liquid impermeable at atmospheric pressure and prevents sample from flowing through the open luer end when coupled to a sample tube containing a specimen. Under vacuum, the liquid sample fraction of the specimen can be drawn through the filter matrix and into the microfluidic testing device through the luer connection for diagnostic analysis.

    Abstract translation: 公开了用于收集临床标本并将其样品递送到例如用于诊断分析的微流体测试装置的样本收集和递送装置。 样品收集和输送装置包括用于在一端与样品管连接的封闭壳体,用于与在另一端的微流体装置上的互补鲁棒耦合的开口鲁尔以及设置在内部的过滤器矩阵。 过滤器基体在大气压力下是透气的和液体不可渗透的,并且当与包含样品的样品管相耦合时,防止样品流过开口鲁尔端。 在真空下,样品的液体样品分数可以通过过滤器基质并通过鲁尔连接进入微流体测试装置进行诊断分析。

    MICROFLUIDIC MIXING DEVICE AND METHOD
    5.
    发明公开

    公开(公告)号:EP3416738A1

    公开(公告)日:2018-12-26

    申请号:EP17708105.6

    申请日:2017-02-17

    Abstract: A microfluidic mixing device comprising two bellows pumps (105, 115), microfluidic cartridges comprising the same and methods for use of the same are provided. The disclosed device enables efficient mixing of samples at the microfluidic scale. More particularly, the microfluidic mixing device comprises: a first bellows pump (105); a second bellows pump (115); a first microchannel fluidly interconnecting the first bellows pump (105) with a sample inlet and a reagent reservoir, wherein the first microchannel comprises a valve (V10) interposed between the pump and the inlet, and a valve (V1) interposed between the pump and the reservoir; a second microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump (115), wherein the second micro channel comprises a valve (V11) interposed between the first and second pump; a third microchannel fluidly interconnecting the first bellows pump (105) with the second bellows pump, wherein the third micro channel comprises a valve (V11) interposed between the first and second pump; a first and second pneumatic member pneumatically connected to the first and second bellows pumps; wherein, the volume of the second bellows pump (115) is greater than the volume of the first bellows pump (105).

Patent Agency Ranking