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公开(公告)号：EP2959275A4
公开(公告)日：2016-12-14
申请号：EP14754054
申请日：2014-02-19
Applicant: NAT UNIV SINGAPORE
Inventor： HUANG ZHIWEI , BERGHOLT MADS SYLVEST , ZHENG WEI , HO KHEK YU
CPC classification number: A61B5/0075 , A61B1/00165 , A61B5/0084 , G01J3/0218 , G01J3/0272 , G01J3/18 , G01J3/28 , G01J3/44 , G01N21/65 , G01N2201/129 , G02B23/2469 , G02B23/26
Abstract: A diagnostic instrument comprises a monochromatic light source, transmission means to transmit light from the light source to a test site, collection means to transmit scattered light from the test site, and spectral analysis apparatus to receive light from the collection means, the spectral analysis apparatus comprising a diffraction grating having a first grating element and a second grating element, wherein the first grating element diffracts light within a first wavelength range and the second grating element diffracts light within a second wavelength range, the spectral analysis apparatus further comprising a light-sensing apparatus, the first grating element arranged to diffract light onto a first area of the light-sensing apparatus and the second grating element arranged to diffract light onto a second area of the light-sensing apparatus.
Abstract translation: 诊断仪器包括单色光源，将光从光源透射到测试部位的传输装置，用于传输来自测试部位的散射光的收集装置，以及用于从收集装置接收光的光谱分析装置，光谱分析装置 包括具有第一光栅元件和第二光栅元件的衍射光栅，其中所述第一光栅元件衍射第一波长范围内的光，所述第二光栅元件在第二波长范围内衍射光，所述光谱分析设备还包括光感测 装置，第一光栅元件被布置成将光衍射到光感测装置的第一区域上，第二光栅元件被布置成将光衍射到光感测装置的第二区域上。
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公开(公告)号：CA2917308C
公开(公告)日：2021-07-13
申请号：CA2917308
申请日：2013-07-02
Applicant: NAT UNIV SINGAPORE
Inventor： HUANG ZHIWEI , HO KHEK YU , BERGHOLT MADS SYLVEST , ZHENG WEI , YEOH KHAY GUAN , DURAIPANDIAN SHIYAMALA
IPC: G01N21/65 , A61B5/00 , A61B6/00 , G01J3/44 , G01N33/574
Abstract: A method of achieving instrument independent measurements for quantitative analysis of fiber-optic Raman spectroscope system, the system comprising a laser source, a spectroscope and a fiber optic probe to transmit light from the laser source to a target and return scattered light to the spectroscope, the method comprising transmitting light from the laser source to a standard target having a known spectrum, recording a calibration spectrum of the scattered light from the standard target, comparing the known spectrum and the calibration system and generating a probe and/or probe-system transfer function, and storing the transfer function. Further provided is a method of performing real-time diagnostic Raman spectroscopy optionally in combination with the other disclosed methods.
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公开(公告)号：ES2930428T3
公开(公告)日：2022-12-12
申请号：ES13813251
申请日：2013-07-02
Applicant: NAT UNIV SINGAPORE
Inventor： HUANG ZHIWEI , HO KHEK YU , BERGHOLT MADS SYLVEST , ZHENG WEI , YEOH KHAY GUAN , DURAIPANDIAN SHIYAMALA
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