公开(公告)号：US20180136193A1

公开(公告)日：2018-05-17

申请号：US15846883

申请日：2017-12-19

Applicant: Nueon Inc.

Inventor： Robert G. Messerschmidt ,  Howland D.T. Jones

IPC: G01N33/49 ,  G01N21/35 ,  G01N33/80

CPC classification number: G01N33/492 ,  A61B5/0082 ,  A61B5/021 ,  A61B5/02108 ,  A61B5/14546 ,  A61B5/1455 ,  G01J3/42 ,  G01N21/35 ,  G01N21/552 ,  G01N33/80 ,  G01N2201/129 ,  G01N2333/805 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/52 ,  G16H10/40

Abstract: Biomarkers of high blood pressure are measured to identify high blood pressure of the subject based on one or more biomarkers. In many embodiments, the response of the biomarker to blood pressure occurs over the course of at least an hour, such that the high blood pressure identification is based on a cumulative effect of physiology of the subject over a period of time. The methods and apparatus of identifying high blood pressure with biomarkers have the advantage of providing improved treatment of the subject, as the identified biomarker can be related to an effect of the high blood pressure on the subject, such as a biomarker corresponding to central blood pressure. The sample can be subjected to increases in one or more of pressure or temperatures, and changes in the blood sample measured over time.

公开(公告)号：US11371882B2

公开(公告)日：2022-06-28

申请号：US16947971

申请日：2020-08-26

Applicant: NUEON INC.

Inventor： Robert Messerschmidt ,  Howland D.T. Jones

IPC: G01J3/02 ,  G01N21/03 ,  G01N21/552 ,  G01N21/25 ,  G01N33/49

Abstract: Described herein are methods and apparatus for spectroscopic analysis of samples. In many embodiments, an apparatus for providing spectroscopic analysis of a sample comprises a sample holder. For example, the sample holder may comprise a consumable single use sample holder that can be readily coupled to and removed from a measurement apparatus such as a spectrometer. The sample holder may comprise a measurement surface configured to receive the sample during measurement, wherein the measurement surface may comprise a porous mesh. The porous mesh can receive the sample to optimally configure the sample for spectroscopic measurement, as described in further detail herein.

公开(公告)号：US20190226910A1

公开(公告)日：2019-07-25

申请号：US16137012

申请日：2018-09-20

Applicant: NUEON INC.

Inventor： Robert G. Messerschmidt ,  Howland D.T. Jones

IPC: G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01N33/49

CPC classification number: G01J3/0267 ,  G01J3/0264 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/25 ,  G01N21/552 ,  G01N33/49 ,  G01N2021/0339 ,  G01N2021/0346 ,  G01N2021/035

Abstract: Described herein are methods and apparatus for spectroscopic analysis of samples. In many embodiments, an apparatus for providing spectroscopic analysis of a sample comprises a sample holder. For example, the sample holder may comprise a consumable single use sample holder that can be readily coupled to and removed from a measurement apparatus such as a spectrometer. The sample holder may comprise a measurement surface configured to receive the sample during measurement, wherein the measurement surface may comprise a porous mesh. The porous mesh can receive the sample to optimally configure the sample for spectroscopic measurement, as described in further detail herein.