公开(公告)号：JP2007046989A

公开(公告)日：2007-02-22

申请号：JP2005230935

申请日：2005-08-09

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： KAWAI TAKESHI ,  FUKUOKA TAKAHISA

IPC: G01N37/00 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide microarray having a reaction part of high uniformity.
SOLUTION: A plurality of grooves 12 extending almost in parallel to each other are formed to a substrate 11 comprising a silicon wafer, by using a photolithographic process due to a semiconductor process. Next, an alcohol solution of aminosilane is supplied to the end parts of the grooves 12 in a liquid droplet state by a dispensing mechanism, such as a dispensing nozzle 14. The alcohol solution is introduced into the grooves 12 upon the contact with the substrate 11 by the capillary phenomenon due to surface tension. After drying, a PSB of a bifunctional crosslinking agent dissolved in water is further brought into contact with the substrate 11. Thereafter, oligonucleoside 13, having an amino group added thereto being a probe, is brought into contact with the end parts of the grooves 12 by the dispensing nozzle 14 to be introduced into the grooves 12. Subsequently, after subjecting it to reaction the probe is set to solid phase and a reaction part that reacts with a target substance is formed.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：提供具有高均匀性的反应部分的微阵列。 解决方案：通过使用由于半导体工艺的光刻工艺，将包括硅晶片的基板11形成为彼此平行延伸的多个凹槽12。 接下来，氨基硅烷的醇溶液通过诸如分配喷嘴14之类的分配机构以液滴状态供应到槽12的端部部分。当与基板11接触时，将醇溶液引入槽12中 由毛细管现象引起的表面张力。 干燥后，溶解在水中的双功能交联剂的PSB进一步与基板11接触。此后，将其中添加有氨基的寡核苷酸13作为探针与槽12的端部接触 通过分注喷嘴14被引入到凹槽12中。随后，在使其进行反应之后，将探针设定为固相，形成与目标物质发生反应的反应部分。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2005215080A

公开(公告)日：2005-08-11

申请号：JP2004018859

申请日：2004-01-27

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： KAWAI TAKESHI ,  HARADA JIYUNYA

IPC: G02B7/04

Abstract: PROBLEM TO BE SOLVED: To provide a lens driving device for driving a frame member to advance/retreat, whose sliding resistance is made small and which realizes miniaturization. SOLUTION: The camera 1 incorporates the lens driving device and a lens frame unit 7 having a photographic optical system and a CCD, and the lens driving device is provided to drive a 2nd group frame 72 holding a 2nd group lens so as to advance/retreat and has a half nut 82 having a female screw thread part and turnably supported by a sleeve 81 for the guide shaft of the 2nd group frame 72, and a nut pawl 83 having a female screw thread part and turnably supported by the half nut. The half nut 82 and the nut pawl 83 are held on and screwed in the outside diameter part of a feed screw shaft 103. Since the half nut 82 and the nut pawl 83 are turnably supported, unnatural force does not act on the screwed part even when positional deviation between the guide shafts 75 and 76 and the feed screw shaft 103 is caused, and the frame 72 is smoothly driven to advance/retreat. COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种用于驱动框架构件前进/后退的透镜驱动装置，其滑动阻力小并且实现小型化。

解决方案：相机1包括透镜驱动装置和具有摄影光学系统和CCD的透镜框单元7，并且透镜驱动装置被设置成驱动保持第二组透镜的第二组框架72，以便 前进/后退，并具有一个具有内螺纹部分的半螺母82，并且可旋转地由用于第二组框架72的引导轴的套筒81支撑，以及具有内螺纹部分的螺母棘爪83，并且可旋转地由半 坚果。 半螺母82和螺母棘爪83保持在进给螺杆轴103的外径部分上并拧紧。由于半螺母82和螺母棘爪83是可转动地支撑的，所以不自然的力也不会作用在螺纹部分上 当引导轴75和76与进给丝杠轴103之间发生位置偏离时，框架72平稳地被驱动以进退。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2004173204A

公开(公告)日：2004-06-17

申请号：JP2002339717

申请日：2002-11-22

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： KAWAI TAKESHI ,  MATSUMOTO NAOKI ,  YOSHIDA HITOSHI

IPC: G03B17/02 ,  G03B17/17 ,  H04N5/225 ,  H04N101/00

Abstract: PROBLEM TO BE SOLVED: To provide a camera whose thickness in a direction parallel to an incident light axis (first optical axis) of light of an object is thin and which can be made small.
SOLUTION: A lens barrel 10 having a prism 33 for refracting luminous flux of the object downward, an electric substrate unit 5 and a power supply unit 6 arranged to the left and right of the lens barrel 10, an LCD unit 9 disposed at the rear side of the lens barrel 10, and a switch substrate 58 disposed at an upper part of the LCD unit 9 are incorporated in the electronic camera 1 while being covered with front and rear covers 2 and 3. The LCD unit 9 has a light guide plate 17 whose thickness reduces downward, and the lens barrel 10 has a CCD 55 projecting backward at a lower side and a CCD substrate 56. A CCD side being a projecting side of the lens barrel 10 is arranged oppositely to a side where the thickness of the LCD unit 9 is thin to be housed in the camera so that the camera can be made thinner.
COPYRIGHT: (C)2004,JPO

公开(公告)号：JP2006340686A

公开(公告)日：2006-12-21

申请号：JP2005171208

申请日：2005-06-10

Applicant: OLYMPUS CORP

Inventor： MATSUO YUICHIRO ,  TAKAGI KOSUKE ,  KAWAI TAKESHI

IPC: C12Q1/06 ,  C12M1/34 ,  G01N21/64 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To accurately count number of cells by reducing load of examiners and inspection mistakes. SOLUTION: The cell analysis method comprises a process for inputting image information accepting lights emitted from cells as two or more images with a predetermined interval, a luminance value operation process for calculating a rate of presence of pixel over a predetermined value of two or more images obtained in the process for inputting the image information and a comparative operation process for comparatively operating the rate of presence of pixel over the predetermined value of two or more images obtained in the process for inputting the image information. COPYRIGHT: (C)2007,JPO&INPIT

公开(公告)号：JP2006145393A

公开(公告)日：2006-06-08

申请号：JP2004336160

申请日：2004-11-19

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： KAWAI TAKESHI

IPC: G01N21/03 ,  G01N21/01

Abstract: PROBLEM TO BE SOLVED: To provide a measuring container for reducing fluctuation of a distance between an objective lens and a sample, and a holding mechanism for holding the measuring container.
SOLUTION: In this measuring container formed with a plurality of sample vessels having an opening part in a container surface side, a measuring area 2a with a bottom face 2 formed of an optically transparent member, constituted to position the bottom face 2 in an inner side of a grounding portion of a frame 1, and for observing/measuring the sample inside the sample vessel 3 through the bottom face 2, the bottom face 2 is formed greater than the measuring area 2a, and a size thereof has at least a size allowing support in an area 2b other than the measuring area 2a, by a support member 21.
COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种用于减小物镜与样品之间的距离的波动的测量容器以及用于保持测量容器的保持机构。 解决方案：在容器表面侧具有开口部的多个样本容器的测量容器中，具有由光学透明构件形成的底面2的测量区域2a，其被构造成将底面2定位在 框架1的接地部分的内侧，并且通过底面2观察/测量样品容器3内的样品，底面2形成为大于测量区域2a，其尺寸至少为 通过支撑构件21允许在除了测量区域2a之外的区域2b中支撑的尺寸。版权所有（C）2006，JPO＆NCIPI

公开(公告)号：JP2007020449A

公开(公告)日：2007-02-01

申请号：JP2005205574

申请日：2005-07-14

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： TAKAGI KOSUKE ,  SHIMADA YOSHIHIRO ,  MATSUO YUICHIRO ,  KAWAI TAKESHI

IPC: C12Q1/02 ,  C12M1/34 ,  G01N33/15 ,  G01N33/50 ,  G06T1/00

Abstract: PROBLEM TO BE SOLVED: To carry out the screening of medicines in high accuracy by using a proper morphological character.
SOLUTION: The screening method comprises the analysis of cell images photographed by a microscope, the evaluation of the parameterized value of the deviation of the contour of the cell from circles C
I and C
O as a morphological character representing the morphological character of each cell in the cell images and the screening of medicines based on the evaluation.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：通过适当的形态特征，高精度地进行药物筛选。 解决方案：筛选方法包括通过显微镜拍摄的细胞图像的分析，细胞轮廓偏离参数值的评估圆圈C I 和C O 作为代表细胞图像中的每个细胞的形态特征和基于评估的药物筛选的形态特征。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2007215472A

公开(公告)日：2007-08-30

申请号：JP2006039184

申请日：2006-02-16

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： MATSUO YUICHIRO ,  KAWAI TAKESHI ,  SHIMADA YOSHIHIRO

IPC: C12M1/22 ,  C12M3/00 ,  C12M3/06

CPC classification number: C12M23/10 ,  C12M23/34 ,  C12M25/02 ,  C12M27/22

Abstract: PROBLEM TO BE SOLVED: To provide a cell culture container which enables the free selection of a timing and amount for supplying a biochemical substance or the like secreted from one kind of cells in a culture process to the other kind of cells, and thereby facilitating finer observation of the culture.
SOLUTION: This cell culture container is characterized by disposing a dividing wall 2b for approximately horizontally dividing culture regions X, Y for culturing the cells A, B therein in the culture regions X, Y, disposing passages 3 permitting the pass of a culture solution 5 in the dividing wall 2b, and disposing filter members 4 permitting the pass of the culture solution 5 but inhibiting the pass of the cells A, B and an opening or closing means 6 for opening or closing the pass 3 in the dividing wall 2b.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 待解决的问题：提供一种细胞培养容器，其能够自由选择将培养过程中从一种细胞分泌的生物化学物质等供给另一种细胞的时间和量，以及 从而促进对文化的更好的观察。 解决方案：该细胞培养容器的特征在于在培养区域X，Y中设置用于大致水平分割用于培养细胞A，B的培养区域X，Y的分隔壁2b， 分离壁2b中的培养液5，并且设置允许培养液5通过但阻止细胞A，B通过的过滤器部件4和用于打开或关闭分隔壁中的通过部3的打开或关闭装置6 2B。 版权所有（C）2007，JPO＆INPIT