公开(公告)号：WO2004106903A8

公开(公告)日：2005-04-07

申请号：PCT/JP2004007442

申请日：2004-05-25

Applicant: OLYMPUS CORP ,  NAMBA AKIHIRO ,  SAWADA RYUJI

Inventor： NAMBA AKIHIRO ,  SAWADA RYUJI

IPC: G01N21/64 ,  G02B21/00

CPC classification number: G01N21/76 ,  G01N21/6458 ,  G02B21/0076

Abstract: A measuring device (100) comprising a cofocal-point optical microscope (110), an excitation light source unit (130) that emits an excitation light for generating fluorescence from a fluorescent material, and a light receiving unit (140). The cofocal-point optical microscope (110) has an excitation light input port (112) for capturing an excitation light from the excitation light source unit (130), and an output port (113) for outputting fluorescence generated by an excitation light. The light receiving unit (140) has an input unit (141) for capturing a signal light including fluoresence from the microscope (110). The input unit (141) of the light receiving unit (140) is optically connected to the output port (113) of the microscope (110) via an optical fiber (153).

Abstract translation: 包括共焦点光学显微镜（110）的测量装置（100），发射用于从荧光材料产生荧光的激发光的激发光源单元（130）和光接收单元（140）。 共焦点光学显微镜（110）具有用于捕获来自激发光源单元（130）的激发光的激发光输入端口（112）和用于输出由激发光产生的荧光的输出端口（113）。 光接收单元（140）具有用于从显微镜（110）捕获包括荧光的信号光的输入单元（141）。 光接收单元（140）的输入单元（141）经由光纤（153）与显微镜（110）的输出端口（113）光学连接。

公开(公告)号：AT503177T

公开(公告)日：2011-04-15

申请号：AT04734732

申请日：2004-05-25

Applicant: OLYMPUS CORP

Inventor： NAMBA AKIHIRO ,  SAWADA RYUJI

IPC: G01N21/64 ,  G02B21/00

Abstract: Onto a surface of an Al x Ga y In 1-x-y As z P 1-z (0‰¤x, y, z‰¤1) layer including GaAs alone or an InP substrate, an electron beam controlled to an arbitrary electron beam diameter and current density is irradiated so as to selectively substitute or generate Ga 2 O 3 for a natural oxide layer formed on the Al x Ga y In 1-x-y As z P 1-z layer surface, then the Al x Ga y In 1-x-y As z P 1-z layer surface is dry-etched by a bromide in single atomic layer units, whereby the natural oxide layer other than the part substituted by the Ga 2 O 3 and Al x Ga y In 1-x-y As z P 1-z substrate are removed.

公开(公告)号：EP1637871A4

公开(公告)日：2008-03-12

申请号：EP04734732

申请日：2004-05-25

Applicant: OLYMPUS CORP

Inventor： NAMBA AKIHIRO ,  SAWADA RYUJI

IPC: G01N21/64 ,  G02B21/00

CPC classification number: G01N21/76 ,  G01N21/6458 ,  G02B21/0076

Abstract: A measuring device (100) comprising a cofocal-point optical microscope (110), an excitation light source unit (130) that emits an excitation light for generating fluorescence from a fluorescent material, and a light receiving unit (140). The cofocal-point optical microscope (110) has an excitation light input port (112) for capturing an excitation light from the excitation light source unit (130), and an output port (113) for outputting fluorescence generated by an excitation light. The light receiving unit (140) has an input unit (141) for capturing a signal light including fluoresence from the microscope (110). The input unit (141) of the light receiving unit (140) is optically connected to the output port (113) of the microscope (110) via an optical fiber (153).

公开(公告)号：JP2012187306A

公开(公告)日：2012-10-04

申请号：JP2011054275

申请日：2011-03-11

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： HIBINO HIROKI ,  SAWADA RYUJI

IPC: A61B5/1473 ,  A61F2/84 ,  A61M5/32

Abstract: PROBLEM TO BE SOLVED: To provide a sensor insertion apparatus in which even a flexible biosensor can be indwelled without being transformed after inserted under the skin.SOLUTION: The sensor insertion apparatus 10 includes a long and thin needle shape section 12 that accommodates a strip sensor piece 3 inserted under the skin and measuring biological information in the long axis direction to be extracted from the tip, wherein a blade surface 15 comprising a surface substantially parallel to the short axis of the sensor piece 3 accommodated in the needle shape section 12 is disposed at the tip of the needle shape section 12. According to the present invention, the sensor piece 3 is inserted substantially vertically to the direction in which the blade surface 15 pushes to expand a puncture hole, thereby that the pressure of the surface direction to the sensor piece 3 from the peripheral tissue is acted can be prevented.

Abstract translation: 要解决的问题：提供一种传感器插入装置，其中甚至柔性生物传感器可以在插入皮肤之后不被变形而被留置。 解决方案：传感器插入装置10包括长且细的针形部分12，其容纳插入皮肤下面的条状传感器片3，并测量从尖端提取的沿长轴方向的生物信息，其中刀片表面 包括基本上平行于容纳在针形部分12中的传感器片3的短轴的表面15设置在针状部分12的尖端处。根据本发明，传感器片3基本上垂直于 可以防止叶片表面15推动穿刺孔的方向，从而可以防止来自周边组织的传感器片3的表面方向的压力作用。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2014226157A

公开(公告)日：2014-12-08

申请号：JP2013105393

申请日：2013-05-17

Applicant: オリンパス株式会社 ,  Olympus Corp

Inventor： SAWADA RYUJI

IPC: A61B17/34

Abstract: 【課題】心臓が最も拡張している瞬間に穿刺針が心膜を破った場合にもガイドワイヤを心膜腔内に導入する。【解決手段】長手方向に貫通する貫通孔を有するとともに、一端に尖端2aを有する筒状の穿刺針2と、該穿刺針2を長手方向に移動可能に収容し、穿刺針2の尖端2aを出没させる先端開口3aを有する外筒部3と、穿刺針2の尖端2aを先端開口3aから外側に突出させた状態で、穿刺針2の外筒部3に対する長手方向の移動を固定する一方、穿刺針2の尖端2aに長手軸に交差する方向の力が作用した場合に固定を解除する係止手段4とを備えるガイド装置1を提供する。【選択図】図1

Abstract translation: 要解决的问题：为了提供一种引导装置，即使在心脏延伸最多的时刻，即使穿刺针撕裂心包，也将导丝引入心包空间。导引装置1包括：圆柱形穿刺针2，其具有 沿纵向贯穿的通孔，在一端具有点2a; 外周筒部3，其沿长度方向可移动地容纳穿刺针2，并且具有缩回穿刺针2的点2a的前端开口3a; 以及将穿刺针2的点2a从前端开口3a突出到外部时将穿刺针2的纵向运动固定在外筒部3上的锁定装置4，或者当将穿刺针2的力 与纵轴相交的方向作用在穿刺针2的点2a上。

公开(公告)号：JP2013088137A

公开(公告)日：2013-05-13

申请号：JP2011225997

申请日：2011-10-13

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： HYAKUMURA KAZUJI ,  SAWADA RYUJI

IPC: G01N21/47 ,  G01N21/27 ,  G01N21/39

Abstract: PROBLEM TO BE SOLVED: To provide a scattering coefficient measuring device which is capable of measuring a scattering coefficient of a sample while attaining reduction in the device size.SOLUTION: A scattering coefficient measuring device 1 is adopted which comprises: a light guide section 10 which emits light obliquely to a surface of a sample A; a plurality of photodetectors 20 arrayed, in the emission direction, around a light incident point on the surface of the sample A each for detecting the intensity of scattered light from the surface of the sample A; and a CPU 30 which calculates a scattering coefficient of the sample A from the distribution of the intensity of scattered light from the sample A detected by the photodetectors 20.

Abstract translation: 要解决的问题：提供一种能够在减小装置尺寸的同时测量样品的散射系数的散射系数测量装置。 解决方案：采用散射系数测量装置1，其包括：向样品A的表面倾斜发射光的导光部10; 多个光电检测器20沿发射方向排列在样品A表面上的光入射点，用于检测来自样品A的表面的散射光的强度; 以及CPU30，其根据由光电检测器20检测到的来自样品A的散射光的强度的分布来计算样品A的散射系数。（C）2013，JPO和INPIT

公开(公告)号：JP2004361087A

公开(公告)日：2004-12-24

申请号：JP2003155993

申请日：2003-05-30

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： SAWADA RYUJI ,  NANBA AKIHIRO

IPC: G01N21/64

Abstract: PROBLEM TO BE SOLVED: To grasp various movements or changes of a target specimen by performing a focus control of high precision in an optical axis direction corresponding to a plurality of focuses.
SOLUTION: The biomolecule analyzer is equipped with an image acquiring means (29) for acquiring an image containing the three-dimensional region corresponding to at least one observation region of a biological specimen (S) containing a biomolecule, an arranging means (20 or 25) for arranging a measuring point on an arbitrary position on the three-dimensional region in the image of the specimen acquired by the image acquiring means, a measuring means (10a and 10b) for measuring the signal originating from the dynamic data of a substance to be measured obtained from the measuring point arranged by the arranging means through an object lens (5) and an analyzing-means (20) for analyzing the result measured by the measuring means. In the arranging means, the measuring point is arranged at an arbitrary position in an optical direction by the movement of the predetermined lens arranged on the optical axis of the object lens in the optical direction.
COPYRIGHT: (C)2005,JPO&NCIPI

公开(公告)号：JP2004347562A

公开(公告)日：2004-12-09

申请号：JP2003147683

申请日：2003-05-26

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： SAWADA RYUJI

IPC: G01N21/64

Abstract: PROBLEM TO BE SOLVED: To provide a measuring apparatus for appropriately coping with fluorescent measurement, where conditions differ diversely.
SOLUTION: The measuring apparatus comprises a photodetecting apparatus 6 for detecting intensity in fluorescence from a sample 9 for varying photoreception sensitivity for outputting light intensity values; a statistical analysis apparatus 7 for statistically analyzing the light intensity values detected by the photodetecting apparatus 6; and a photoreception sensitivity setting apparatus 10 for outputting photoreception sensitivity setting values for setting the photoreception sensitivity of the photodetecting apparatus 6. The photoreception sensitivity setting values of the photoreception sensitivity setting apparatus 10 are determined so that the photoreception sensitivity of the photodetecting apparatus 6 becomes optimum depending on measuring conditions.
COPYRIGHT: (C)2005,JPO&NCIPI

公开(公告)号：JP2014161610A

公开(公告)日：2014-09-08

申请号：JP2013037082

申请日：2013-02-27

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： SAWADA RYUJI

IPC: A61B17/34

Abstract: PROBLEM TO BE SOLVED: To provide a fixing tool capable of stably fixing a medical instrument to a tissue while protecting a thinned incisal portion of the tissue due to an incision.SOLUTION: A fixing tool 1 comprises: a cylindrical body 2 that allows insertion of a medical instrument 50 and is attached on an outer peripheral surface of the medical instrument 50; and two holding members 3 and 4 that are arranged on an outer peripheral surface of the body 2 at intervals in a longitudinal direction and hold a tissue by pinching it in the longitudinal direction. The holding members 3 and 4 respectively include a contact section 7 capable of relatively moving in the longitudinal direction between a position of contacting in the longitudinal direction and a mutually separating position, and these contact sections 7 contact each other at a position outwardly apart in a radial direction from the outer peripheral surface of the body.

Abstract translation: 要解决的问题：提供一种能够将医疗器械稳定地固定在组织上的固定工具，同时保护由于切口而导致的组织的变薄的切口部分。解决方案：固定工具1包括：圆柱体2， 医疗器械50，并且附接在医疗器械50的外周面上; 以及两个保持构件3和4，其沿长度方向间隔设置在主体2的外周面上，并且通过在纵向方向上夹持来夹持组织。 保持构件3和4分别包括能够在纵向方向上接触的位置和相互分离位置之间在纵向上相对移动的接触部分7，并且这些接触部分7在一个位置向外分开的位置处彼此接触 径向从身体的外周表面。

公开(公告)号：JP2012130567A

公开(公告)日：2012-07-12

申请号：JP2010286300

申请日：2010-12-22

Applicant: Olympus Corp ,  オリンパス株式会社

Inventor： SAWADA RYUJI

IPC: A61B5/157 ,  A61B5/1459 ,  A61B5/151

Abstract: PROBLEM TO BE SOLVED: To ensure washability of skin when embedding a biosensor into the inside of a body.SOLUTION: A biosensor embedding device 1 includes: an introducing needle 4 which has a biosensor 2 attached to the distal end and is provided movably between a storage position and a puncture position at which it is projected to the distal end side more than the storage position and is capable of puncturing the skin; a disinfection means 5 for disinfecting the skin; and a puncture permission means for permitting the movement to the puncture position of the introducing needle 4 by the operation of the disinfection means 5.

Abstract translation: 要解决的问题：当将生物传感器嵌入身体内部时，确保皮肤的洗涤性。 生物传感器嵌入装置1包括：引导针4，其具有附接到远端的生物传感器2，并且可移动地设置在存储位置和穿刺位置之间，在该位置，其突出到远端侧 存储位置并且能够刺穿皮肤; 用于消毒皮肤的消毒装置5; 以及穿刺允许装置，用于通过消毒装置5的操作允许移动到引入针4的穿刺位置。（C）2012年，JPO和INPIT