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    MEANS AND METHODS FOR DETECTING BACTERIA IN AN AEROSOL SAMPLE
    1.
    发明申请
    MEANS AND METHODS FOR DETECTING BACTERIA IN AN AEROSOL SAMPLE 审中-公开
    用于检测气溶胶样品中细菌的方法和方法

    公开(公告)号：WO2010032245A3

    公开(公告)日：2010-05-20

    申请号：PCT/IL2009000908

    申请日：2009-09-16

    Applicant: OPTICUL DIAGNOSTICS LTD ,  BEN-DAVID MOSHE ,  GANNOT GALLYA ,  ERUV TOMER ,  MARKOWITZ ZVI

    Inventor： BEN-DAVID MOSHE ,  GANNOT GALLYA ,  ERUV TOMER ,  MARKOWITZ ZVI

    IPC: G06K9/00 ,  G01N33/50

    CPC classification number: G06K9/00496

    Abstract: This disclosure provides a method for detecting and/or identifying uncultured bacteria. The sample is an aerosol sample selected from a group consisting of cough, sneeze, saliva, mucus, bile, urine, vaginal secretions, middle ear aspirate, pus, pleural effusions, synovial fluid, abscesses, cavity swabs, serum, blood and spinal fluid. The method comprises obtaining absorption spectra (AS) of the sample, extracting and processing the acquired data, thereby detecting and/or identifying the bacteria.

    Abstract translation: 本公开提供了用于检测和/或识别未培养的细菌的方法。 样品是选自咳嗽，打喷嚏，唾液，粘液，胆汁，尿液，阴道分泌物，中耳抽吸物，脓液，胸腔积液，滑液，脓肿，腔拭子，血清，血液和脊髓液的气溶胶样品 。 该方法包括获得样品的吸收光谱（AS），提取和处理所获取的数据，从而检测和/或识别细菌。

    MEANS AND METHODS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA IN A SAMPLE
    2.
    发明申请
    MEANS AND METHODS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA IN A SAMPLE 审中-公开
    用于检测样品中抗生素抗细菌的方法和方法

    公开(公告)号：WO2010041251A3

    公开(公告)日：2010-06-03

    申请号：PCT/IL2009000960

    申请日：2009-10-11

    Applicant: OPTICUL DIAGNOSTICS LTD ,  BEN-DAVID MOSHE ,  GANNOT GALLYA ,  ERUV TOMER ,  MARKOWITZ ZVI

    Inventor： BEN-DAVID MOSHE ,  GANNOT GALLYA ,  ERUV TOMER ,  MARKOWITZ ZVI

    IPC: G06K9/00 ,  G01N33/50

    CPC classification number: G06K9/00496

    Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample, comprising steps of: a. obtaining an absorption spectrum (AS) of said uncultured sample; b. acquiring the n dimensional volume boundaries for said specific bacteria; c. data processing said AS; i. noise reducing; ii. extracting m features from said entire AS; iii. dividing said AS into several segments according to said m features; iv. calculating m 1 features of each of said segment; and, d. detecting and/or identifying said specific bacteria if said m 1 features and/or said m features are within said n dimensional volume; wherein said bacteria is a antibiotics resistance bacteria.

    Abstract translation: 本发明提供了用于检测和/或鉴定未培养样品内的特定细菌的方法，包括以下步骤：a。 获得所述未培养样品的吸收光谱（AS） 湾 获取所述特定细菌的n维体积边界; C。 数据处理所述AS; 一世。 降噪; II。 从所述整个AS中提取m个特征; III。 根据所述m个特征将所述AS划分成若干段; IV。 计算每个所述片段的m 1个特征; 和，d。 如果所述m 1特征和/或所述m个特征在所述n维体积内，则检测和/或识别所述特定细菌; 其中所述细菌是抗生素抗性细菌。

    СПОСОБ СПЕКТРАЛЬНОГО ОБНАРУЖЕНИЯ И ИДЕНТИФИКАЦИИ МИКРООРГАНИЗМОВ В КУЛЬТУРЕ
    3.
    发明专利
    СПОСОБ СПЕКТРАЛЬНОГО ОБНАРУЖЕНИЯ И ИДЕНТИФИКАЦИИ МИКРООРГАНИЗМОВ В КУЛЬТУРЕ 未知

    公开(公告)号：EA033790B1

    公开(公告)日：2019-11-26

    申请号：EA201400824

    申请日：2012-12-19

    Applicant: OPTICUL DIAGNOSTICS LTD ,  OPTICUL DIAGNOSTICS INC

    Inventor： GANNOT GALLYA ,  LEDERMAN DROR ,  MOINUDDIN HASSAN ,  GANNOT ISRAEL

    IPC: G01N21/00 ,  G01N21/25 ,  G01N33/00

    Abstract: Раскрываетсяспектроскопическийспособдляспектроскопическогообнаруженияи идентификациибактерийв культуре. Способвключаетв себяпостроениепоменьшеймереодногонабораданных, которыйможетвключатьспектр, интерференционнуюкартинуиликартинурассеяниякультивированногообразца, предположительносодержащегоуказанныебактерии. Наборданныхкорректируетсянаналичиеводыв образце, спектральныепризнакиизвлекаютсяс помощьюанализаглавныхкомпонентов, афункцииклассификацииполученыс использованиемалгоритмаобучения. Внекоторыхвариантахосуществленияизобретения, напримердлядифференциации MRSA из MSSA, используетсямультимодальныйанализ, вкоторомидентификациябактерийвыполненанаосновеспектраобразца, интерференционнойкартины, используемойдляопределениятолщиныклеточнойстенки, ирассеяния, используемогодляопределенияшероховатостиклеточнойстенки. Такжераскрытодинвариантустройствадляосуществленияспособа, которыйвключаетв себянесколькоанализаторовобразцов.

    MEANS AND METHODS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA IN A SAMPLE
    4.
    发明专利
    MEANS AND METHODS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA IN A SAMPLE 未知

    公开(公告)号：CA2738813A1

    公开(公告)日：2010-04-15

    申请号：CA2738813

    申请日：2009-10-11

    Applicant: OPTICUL DIAGNOSTICS LTD

    Inventor： BEN-DAVID MOSHE ,  GANNOT GALLYA ,  ERUV TOMER ,  MARKOWITZ ZVI

    IPC: G06K9/00 ,  G01N33/50

    Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample, comprising steps of: a. obtaining an absorption spectrum (AS) of said uncultured sample; b. acquiring the n dimensional volume boundaries for said specific bacteria; c. data processing said AS; i. noise reducing; ii. extracting m features from said entire AS; iii. dividing said AS into several segments according to said m features; iv. calculating m 1 features of each of said segment; and, d. detecting and/or identifying said specific bacteria if said m 1 features and/or said m features are within said n dimensional volume; wherein said bacteria is a antibiotics resistance bacteria.

    MEANS AND METHODS FOR DETECTING BACTERIA IN A SAMPLE
    5.
    发明专利
    MEANS AND METHODS FOR DETECTING BACTERIA IN A SAMPLE 未知

    公开(公告)号：CA2683142A1

    公开(公告)日：2008-10-16

    申请号：CA2683142

    申请日：2008-04-06

    Applicant: OPTICUL DIAGNOSTICS LTD

    Inventor： ERUV TOMER ,  GANNOT GALLYA ,  BEN-DAVID MOSHE

    IPC: C12Q1/04 ,  G16B45/00

    Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample. The method comprises steps se lected inter alia from (a) obtaining an absorption spectrum (AS) of said unc ultured sample; (b) acquiring the n dimensional volume boundaries for said s pecific bacteria; (c) data processing said AS; and, (d) detecting and/or ide ntifying said specific bacteria if said m1 statistical correlation and/or sa id m features are within said n dimensional volume.

    SPECTROSCOPIC MEANS AND METHODS FOR IDENTIFYING MICROORGANISMS IN CULTURE
    6.
    发明专利
    SPECTROSCOPIC MEANS AND METHODS FOR IDENTIFYING MICROORGANISMS IN CULTURE 未知

    公开(公告)号：CA2859951A1

    公开(公告)日：2013-06-27

    申请号：CA2859951

    申请日：2012-12-19

    Applicant: OPTICUL DIAGNOSTICS INC ,  OPTICUL DIAGNOSTICS LTD

    Inventor： GANNOT GALLYA ,  LEDERMAN DROR ,  MOINUDDIN HASSAN ,  GANNOT ISRAEL

    IPC: C12Q1/04 ,  C12M1/34 ,  G01J3/10 ,  G01N21/01 ,  G01N21/25 ,  G01N33/483 ,  G06F19/10

    Abstract: A spectroscopic method for spectroscopic detection and identification of bacteria in culture is disclosed. The method incorporates construction of at least one data set, which may be a spectrum, interference pattern, or scattering pattern, from a cultured sample suspected of containing said bacteria. The data set is corrected for the presence of water in the sample, spectral features are extracted using a principal components analysis, and the features are classified using a learning algorithm. In some embodiments of the invention, for example, to differentiate MRS A from MSSA, a multimodal analysis is performed in which identification of the bacteria is made based on a spectrum of the sample, an interference pattern used to determine cell wall thickness, and a scattering pattern used to determine cell wall roughness. An apparatus for performing the method is also disclosed, one embodiment of which incorporates a multiple sample analyzer.

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