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Patent Agency Ranking
公开(公告)号：CA2369793A1
公开(公告)日：2000-10-26
申请号：CA2369793
申请日：2000-04-20
Applicant: OPTIX LP
Inventor： GUTHERMANN HOWARD E
IPC: A61B5/0245 , A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/1495
Abstract: The absence of a defined optical path length for in vivo measurements create s problems for the noninvasive measurement of analyte concentration. These problems can be reduced by combining measurements made at several wavelength s and using the fact that normal renal function causes the concentration of water in whole blood to be tightly controlled. Hence, the concentration of water in arterial blood can serve as a useful internal standard for such measurements. The measurements are then procured so as to remove the dependency of concentration on path length traversed by the illuminating radiation and on the scattering properties of the volume through which the illuminating radiation propagates. Using this method, one can create improve d calibration for measurements of absorbing constituents in arterial blood and thereby provide absolute concentration measurements of constituents such as hemoglobin and glucose in arterial blood.
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公开(公告)号：AU4518101A
公开(公告)日：2001-06-25
申请号：AU4518101
申请日：2000-12-06
Applicant: OPTIX LP
Inventor： GUTHERMANN HOWARD E
Abstract: A method of improving the accuracy and reproducibility of non-invasive measurements of a concentration of a constituent of interest carried in a body part has been developed. The method relies on elevating the body part during the measurement cycle so that the body part is maintained above the heart during the measurement cycle. Measurements of the constituent during an arterial pulse leads to improved intra-run and run-to-tun determinations.
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公开(公告)号：AU4366800A
公开(公告)日：2000-11-02
申请号：AU4366800
申请日：2000-04-20
Applicant: OPTIX LP
Inventor： GUTHERMANN HOWARD E
IPC: A61B5/0245 , A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/1495
Abstract: The absence of a defined optical pathlength for in vivo measurements creates problems for the noninvasive measurement of analyte concentration. These problems can be reduced by combining measurements made at several wavelengths and using the fact that normal renal function causes the concentration of water in whole blood to be tightly controlled. Hence, the concentration of water in arterial blood can serve as a useful internal standard for such measurements. The measurements are then procured so as to remove the dependency of concentration on path length traversed by the illuminating radiation and on the scattering properties of the volume through which the illuminating radiation propagates. Using this method, one can create improved calibration for measurements of absorbing constituents in arterial blood and thereby provide absolute concentration measurements of constituents such as hemoglobin and glucose in arterial blood.
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公开(公告)号：WO0143634A3
公开(公告)日：2002-02-14
申请号：PCT/US0042590
申请日：2000-12-06
Applicant: OPTIX LP
Inventor： GUTHERMANN HOWARD E
CPC classification number: G01N21/4795 , A61B5/0059 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14558 , G01N21/359 , G01N21/49 , G01N2021/3137
Abstract: A method of improving the accuracy and reproducibility of non-invasive measurments of a concentration of a constituent of interest carried in a body part has been developed. The method relies on elevating the body part during the measurement cycle so that the body part is maintained above the heart during the measurement cycle. Measurements of the constituent during an arterial pulse leads to improved intra-run and run-to-run determinations.
Abstract translation: 已经开发了提高身体部位携带的感兴趣成分的浓度的非侵入性测量的准确性和可重复性的方法。 该方法依赖于在测量周期内提升身体部位，使得身体部位在测量周期内保持在心脏上方。 在动脉脉搏期间对成分的测量导致改进的运行内和跑步运行测定。
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