公开(公告)号：US20220184277A1

公开(公告)日：2022-06-16

申请号：US17681064

申请日：2022-02-25

Applicant: OSIRIS THERAPEUTICS, INC.

Inventor： Dana Sue YOO ,  Jin-Qiang KUANG ,  Jaime PADEN ,  Scott A. MAXSON ,  Alla DANILKOVITCH ,  Erasmo LOPEZ ,  Samson TOM

IPC: A61L27/36 ,  A61K35/32 ,  A61L27/24 ,  A61L27/38 ,  A61L27/54 ,  A61K38/01 ,  A61L27/56 ,  A61L27/50

Abstract: This invention provides porated cartilage products and methods of producing porated cartilage products. Optionally, the cartilage products are sized, porated, and digested to provide a flexible cartilage product. Optionally, the cartilage products comprise viable chondrocytes, bioactive factors such as chondrogenic factors, and a collagen type II matrix. Optionally, the cartilage products are non-immunogenic.