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公开(公告)号:US20220152411A1
公开(公告)日:2022-05-19
申请号:US17588978
申请日:2022-01-31
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal , Aslak Godal
Abstract: This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2.
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公开(公告)号:US11235168B2
公开(公告)日:2022-02-01
申请号:US16063142
申请日:2016-12-19
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal , Aslak Godal
Abstract: This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2.
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公开(公告)号:US20200155683A1
公开(公告)日:2020-05-21
申请号:US16748332
申请日:2020-01-21
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
Abstract: This invention relates to a neoadjuvant therapy for bladder cancer in bladder cancer patients who are scheduled for a cystectomy and methods of carrying out such a neoadjuvant therapy. In particular, the invention relates to a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a neoadjuvant therapy for bladder cancer in a bladder cancer patient who is scheduled for a cystectomy, the therapy comprises instilling said composition into the bladder of said patient and exposing the inside of said bladder to light.
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公开(公告)号:US20190241672A1
公开(公告)日:2019-08-08
申请号:US16388379
申请日:2019-04-18
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
CPC classification number: C07K16/30 , A61K41/0061 , A61K2039/54 , A61P35/00 , C07K16/2818 , C07K16/2827
Abstract: This invention relates to an intravesical therapy for bladder cancer.
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公开(公告)号:US11311620B2
公开(公告)日:2022-04-26
申请号:US16748332
申请日:2020-01-21
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
Abstract: This invention relates to a neoadjuvant therapy for bladder cancer in bladder cancer patients who are scheduled for a cystectomy and methods of carrying out such a neoadjuvant therapy. In particular, the invention relates to a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a neoadjuvant therapy for bladder cancer in a bladder cancer patient who is scheduled for a cystectomy, the therapy comprises instilling said composition into the bladder of said patient and exposing the inside of said bladder to light.
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公开(公告)号:US11066478B2
公开(公告)日:2021-07-20
申请号:US16388379
申请日:2019-04-18
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
Abstract: This invention relates to an intravesical therapy for bladder cancer.
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公开(公告)号:US20190022404A1
公开(公告)日:2019-01-24
申请号:US16063142
申请日:2016-12-19
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal , Aslak Godal
Abstract: This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2
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公开(公告)号:US11980772B2
公开(公告)日:2024-05-14
申请号:US17588978
申请日:2022-01-31
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal , Aslak Godal
CPC classification number: A61N5/062 , A61K41/0061 , A61B1/307 , A61N2005/061 , A61N2005/0663
Abstract: This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2.
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公开(公告)号:US10556010B2
公开(公告)日:2020-02-11
申请号:US16063185
申请日:2016-12-19
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
Abstract: This invention relates to a neoadjuvant therapy for bladder cancer in bladder cancer patients who are scheduled for a cystectomy and methods of carrying out such a neoadjuvant therapy. In particular the invention relates to a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a neoadjuvant therapy for bladder cancer in a bladder cancer patient who is scheduled for a cystectomy, the therapy comprises instilling said composition into the bladder of said patient and exposing the inside of said bladder to light.
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公开(公告)号:US20180371101A1
公开(公告)日:2018-12-27
申请号:US16063169
申请日:2016-12-19
Applicant: PHOTOCURE ASA
Inventor: Kjetil Hestdal
Abstract: This invention relates to an intravesical therapy for bladder cancer.
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