公开(公告)号：AU2002258277A1

公开(公告)日：2003-09-22

申请号：AU2002258277

申请日：2002-05-17

Applicant: POSTECH FOUNDATION

Inventor： PARK JAIWOOK ,  KIM MAHN-JOO ,  CHOI JUN HO ,  AHN YANGSOO

IPC: C07F15/00 ,  C07F17/00 ,  C07F17/02

Abstract: Novel aminocyclopentadienyl ruthenium complex is useful as a catalyst in the racemization of a chiral compound.

公开(公告)号：AU2002258278A1

公开(公告)日：2003-09-22

申请号：AU2002258278

申请日：2002-05-17

Applicant: POSTECH FOUNDATION

Inventor： PARK JAIWOOK ,  KIM MAHN-JOO ,  CHOI JUN HO ,  AHN YANGSOO

IPC: C07C29/00 ,  C07C29/56 ,  C12P41/00 ,  C07C67/42 ,  C12P7/24 ,  C07F15/00

Abstract: A chiral compound, particularly a chiral secondary alcohol, can be efficiently resolved under a mild condition by acylation with an alkenyl acetate in the presence of a novel aminocyclopentadienyl ruthenium complex, an enzyme catalyst, and a base.

公开(公告)号：CA2478408A1

公开(公告)日：2003-09-18

申请号：CA2478408

申请日：2002-05-17

Applicant: POSTECH FOUNDATION

Inventor： AHN YANGSOO ,  CHOI JUN HO ,  KIM MAHN-JOO ,  PARK JAIWOOK

IPC: C07C29/00 ,  C07C29/56 ,  C12P41/00 ,  C07C67/42 ,  C07F15/00 ,  C12P7/24

Abstract: A chiral compound, particularly a chiral secondary alcohol, can be efficient ly resolved under a mild condition by acylation with an alkenyl acetate in the presence of a novel aminocyclopentadienyl ruthenium complex, an enzyme catalyst, and a base.

公开(公告)号：CA2441430A1

公开(公告)日：2003-07-17

申请号：CA2441430

申请日：2003-01-13

Applicant: POSTECH FOUNDATION ,  POSCO

Inventor： KIM MAHN-JOO ,  LEE JAE KWAN

IPC: C12N9/00 ,  C12N9/20 ,  C12N9/96 ,  C12P41/00 ,  C12S9/00

Abstract: Disclosed is an ionic liquid-coated enzyme, wherein the ionic liquid is an organic salt which presents as a liquid phase at a temperature of about 150~ C or below. The ionic liquid-coated enzyme according to the present invention remarkably improves enzyme functions, such as enantioselectivity and stability, when the enzyme which may be lipase is coated with an ionic liqui d. Further, even in the case of when the ionic liquid-coated enzyme is reused, the enantiomeric excess, enantioselectivity, and activity are not degenerate d. The coated enzyme is usable as a catalyst for providing a chiral intermediat e required in the synthesis of chiral pesticides, medicines, natural chemicals , and so on.

公开(公告)号：AU2003247201A1

公开(公告)日：2005-02-14

申请号：AU2003247201

申请日：2003-07-25

Applicant: POSTECH FOUNDATION ,  POSCO

Inventor： KIM DAEHO ,  KIM MAHN-JOO ,  PARK JAIWOOK ,  CHUNG YONG IL ,  CHOI JUN HO ,  LEE HAN KI ,  CHOI YOON KYUNG

IPC: B01J31/00 ,  B01J31/20 ,  B01J31/22 ,  B01J31/24 ,  C07C29/09 ,  C07C29/143 ,  C07C29/145 ,  C07C67/03 ,  C12P7/02 ,  C12P7/62 ,  C07C29/00 ,  C07F15/00

Abstract: The present invention relates to a method for preparing chiral alcohol having optical activity. More specifically, the present invention relates to a method for preparing (S)-chiral alcohol with a high yield and a high optical purity by mixing achiral substrates such as racemic alcohol or ketone with metal catalyst and protein hydrolase to perform a dynamic kinetic resolution reaction.

公开(公告)号：CA2478410A1

公开(公告)日：2003-09-18

申请号：CA2478410

申请日：2002-05-17

Applicant: POSTECH FOUNDATION

Inventor： AHN YANGSOO ,  PARK JAIWOOK ,  CHOI JUN HO ,  KIM MAHN-JOO

IPC: C07F15/00 ,  C07F17/00 ,  C07F17/02

Abstract: Novel aminocyclopentadienyl ruthenium complex is useful as a catalyst in the racemization of a chiral compound.

公开(公告)号：CA2437251A1

公开(公告)日：2003-06-12

申请号：CA2437251

申请日：2002-12-06

Applicant: POSCO ,  POSTECH FOUNDATION

Inventor： CHOI YOON KYUNG ,  AHN YANGSOO ,  KIM MI JUNG ,  KIM MAHN-JOO

IPC: C12P41/00 ,  C07D311/68 ,  C07D333/36 ,  C12P13/02 ,  C12P17/04 ,  C12P17/10

Abstract: Disclosed is a method of preparing chiral amine. The method includes reactin g ketoxime, palladium, lipase, acyl-donating compound, and tertiary amine to prepare amide, and amide is hydrolyzed.

公开(公告)号：EP1451171A4

公开(公告)日：2004-11-10

申请号：EP02791042

申请日：2002-12-06

Applicant: POSCO ,  POSTECH FOUNDATION

Inventor： KIM MAHN-JOO ,  AHN YANGSOO ,  CHOI YOON KYUNG ,  KIM MI JUNG

IPC: C12P41/00 ,  C07D311/68 ,  C07D333/36 ,  C12P13/02 ,  C12P17/04 ,  C12P17/10 ,  C07C209/40 ,  C07C211/08

CPC classification number: C07D311/68 ,  C12P13/02 ,  C12P17/04 ,  C12P17/10

Abstract: Disclosed is a method of preparing chiral amine. The method includes reacting ketoxime, palladium, lipase, acyl-donating compound, and tertiary amine to prepare amide, and amide is hydrolyzed.

公开(公告)号：EP1483229A4

公开(公告)日：2005-04-20

申请号：EP02728244

申请日：2002-05-17

Applicant: POSTECH FOUNDATION

Inventor： PARK JAIWOOK ,  KIM MAHN-JOO ,  CHOI JUN HO ,  AHN YANGSOO

IPC: C07C29/00 ,  C07C29/56 ,  C12P41/00 ,  C07C67/42 ,  C07F15/00 ,  C12P7/24

CPC classification number: C12P41/004

Abstract: A chiral compound, particularly a chiral secondary alcohol, can be efficiently resolved under a mild condition by acylation with an alkenyl acetate in the presence of a novel aminocyclopentadienyl ruthenium complex, an enzyme catalyst, and a base.