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公开(公告)号：SG175047A1
公开(公告)日：2011-11-28
申请号：SG2011072162
申请日：2010-04-05
Applicant: SCHERING CORP , PTC THERAPEUTICS INC
Inventor： MACCOSS MALCOLM , NJOROGE F GEORGE , NOMEIR AMIN , CHEN GUANGMING , HUANG SONG XIAO , KAKARLA RAMESH , KARP GARY MITCHELL , LENNOX WILLIAM JOSEPH , LI CHUNSHI , LIU RONGGANG , LIU YALEI , MORRILL CHRISTIE , PAGET STEVEN D , SMITH SEAN W , TAKASUGI JAMES , TURPOFF ANTHONY A , REN HONGYU , ZHANG NANJING , ZHANG XIAOYAN , ZHU JIN
Abstract: The present invention is directed to compounds and forms and pharmaceutical compositions thereof useful for treating a viral infection, or for affecting viral activity by modulating viral replication.
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公开(公告)号：CA2757640A1
公开(公告)日：2010-10-14
申请号：CA2757640
申请日：2010-04-05
Applicant: PTC THERAPEUTICS INC
Inventor： MACCOSS MALCOLM , NJOROGE F GEORGE , NOMEIR AMIN , CHEN GUANGMING , HUANG SONG XIAO , KAKARLA RAMESH , KARP GARY MITCHELL , LENNOX WILLIAM JOSEPH , LI CHUNSHI , LIU RONGGANG , LIU YALEI , MORRILL CHRISTIE , PAGET STEVEN D , SMITH SEAN W , TAKASUGI JAMES , TURPOFF ANTHONY A , REN HONGYU , ZHANG NANJING , ZHANG XIAOYAN , ZHU JIN
IPC: C07D401/04 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P31/12 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: The present invention is directed to compounds and forms and pharmaceutical compositions thereof useful for treating a viral infection, or for affecting viral activity by modulating viral replication.
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Patent Agency Ranking
公开(公告)号：MX2011010482A
公开(公告)日：2012-01-30
申请号：MX2011010482
申请日：2010-04-05
Applicant: PTC THERAPEUTICS INC
Inventor： NJOROGE F GEORGE , LENNOX WILLIAM JOSEPH , TAKASUGI JAMES , REN HONGYU , KARP GARY MITCHELL , LI CHUNSHI , ZHANG XIAOYAN , ZHU JIN , LIU RONGGANG , MACCOSS MALCOLM , NOMEIR AMIN , CHEN GUANGMING , HUANG SONG XIAO , KAKARLA RAMESH , LIU YALEI , MORRILL CHRISTIE , PAGET STEVEN D , SMITH SEAN W , TURPOFF ANTHONY A , ZHANG NANJING
IPC: C07D401/04 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P31/12 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: La presente invención está dirigida a compuestos y formas y composiciones farmacéuticas de los mismos, útiles para el tratamiento de una infección viral, o para afectar la actividad viral modulando la replicación viral.
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公开(公告)号：SG175048A1
公开(公告)日：2011-11-28
申请号：SG2011072170
申请日：2010-04-05
Applicant: SCHERING CORP , PTC THERAPEUTICS INC
Inventor： MACCOSS MALCOLM , NJOROGE F GEORGE , NOMEIR AMIN , CHEN GUANGMING , HUANG SONG XIAO , KAKARLA RAMESH , KARP GARY MITCHELL , LENNOX WILLIAM JOSEPH , LI CHUNSHI , LIU RONGGANG , LIU YALEI , MORRILL CHRISTIE , PAGET STEVEN D , SMITH SEAN W , TAKASUGI JAMES , TURPOFF ANTHONY A , REN HONGYU , ZHANG NANJING , ZHANG XIAOYAN , ZHU JIN
Abstract: The present invention is directed to compounds and forms and pharmaceutical compositions thereof useful for treating a viral infection, or for affecting viral activity by modulating viral replication.
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公开(公告)号：NZ596144A
公开(公告)日：2014-01-31
申请号：NZ59614410
申请日：2010-04-05
Applicant: PTC THERAPEUTICS INC
Inventor： HUANG SONG XIAO , MORRILL CHRISTIE , MACCOSS MALCOLM , LIU RONGGANG , KARP GARY MITCHELL , ZHANG NANJING , NJOROGE F GEORGE , REN HONGYU , LI CHUNSHI , NOMEIR AMIN , LENNOX WILLIAM JOSEPH , TURPOFF ANTHONY A , LIU YALEI , ZHANG XIAOYAN , ZHU JIN , KAKARLA RAMESH , SMITH SEAN W , CHEN GUANGMING , TAKASUGI JAMES , PAGET STEVEN D
IPC: C07D401/04 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P31/12 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: 596144 Disclosed herein is a compound of formula (I), wherein the variables are defined in the specification, or a free acid, free base, salt, hydrate, solvate, clathrate, isotopologue, racemate, enantiomer, diastereomer, stereoisomer or polymorph form thereof; and the use of said compound in the treatment of a viral infection, wherein the viral infection is hepatitis C virus. Embodiments of the compound include the following: N-[6-(3-cyano-1-cyclobutyl-6-methoxy-1H-indol-2-yl)pyridazin-3-yl]ethanesulfonamide, and 5-fluoro-6-methyl-1-(pyridin-3-yl)-2-(5-{ [(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl} pyridin-2-yl)-1H-indole-3-carboxamide.
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公开(公告)号：CO6450616A2
公开(公告)日：2012-05-31
申请号：CO11147742
申请日：2011-11-01
Applicant: PTC THERAPEUTICS INC
Inventor： NOMEIR AMIN , HUANG SONG XIAO , KARP GARY MITCHELL , LI CHUNSHI , NJOROGE F GEORGE , CHEN GUANGMING , KAKARLA RAMESH , LENNOX WILLIAM JOSEPH , LIU RONGGANG , LIU YALEI , PAGET STEVEN DAVID , TAKASUGI JAMES , REN HONGYU , ZHANG XIAOYAN , RILL CHRISTIE , SMITH SEAN W , TURPOFF ANTHONY A , ZHANG NANJING , ZHU JIN , MACCOSS MALCOM
IPC: C07D401/04
Abstract: La presente invención se refiere a compuestos o composiciones de indol, o uno de sus ácidos libres, bases libres, sales, hidratos, solvatos, clatratos, isotopólogos, racematos, enantiómeros, diastereómeros, estereoisómeros o sus formas polimórficas.
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公开(公告)号：CR20110542A
公开(公告)日：2012-01-30
申请号：CR20110542
申请日：2011-10-18
Applicant: PTC THERAPEUTICS INC
Inventor： MACCOSS MALCOLM , NJOROGE F GEORGE , NOMEIR AMIN , CHEN GUANGMING , HUANG SONG XIAO , KAKARLA RAMESH , KARP GARY MITCHELL , LENNOX WILLIAM JOSEPH , LI CHUNSHI , LIU RONGGANG , LIU YALEI , MORRILL CHRISTIE , PAGET STEVEN D , SMITH SEAN W , TAKASUGI JAMES , TURPOFF ANTHONY A , REN HONGYU , ZHANG NANJING , ZHANG XIAOYAN , ZHU JIN
IPC: C07D401/04 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/506 , A61P31/12 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: La presente invención se refiere a compuestos y sus formas y composiciones farmacéuticas de utilidad para tratar una infección viral o para afectar la actividad viral al modular la replicación viral.
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