公开(公告)号：WO1993012087A1

公开(公告)日：1993-06-24

申请号：PCT/US1992010822

申请日：1992-12-16

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  GOLLAMUDI, Ramachander ,  FENG, Zixia

IPC: C07D211/60

CPC classification number: C07D211/60

Abstract: The present invention relates to substantially pure stereoisomers of a compound of formula (I) wherein n1 and n2 are the same or different and are 1 or 2; X is alkyl (C1-C10), aryl (C6-C10) or aralkyl (C7-C12); and wherein R, R1, R2 and R3 are the same or different and are chosen from H, alkyl (C1-C10), aryl (C6-C10), aralkyl (C7-C12), or a heterocyclic group, and addition salts thereof with pharmaceutically acceptable acids. The invention also relates to a method for the inhibition of blood platelet aggregation in a blood supply comprising administering to said blood supply a blood platelet aggregation inhibiting amount of the compounds of the present invention.