公开(公告)号：WO1998013336A1

公开(公告)日：1998-04-02

申请号：PCT/US1997017561

申请日：1997-09-26

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  KOHN, Harold

IPC: C07C235/06

CPC classification number: C07C235/34 ,  C07B2200/07 ,  C07C235/06

Abstract: The present invention is directed to a compound useful as an anticonvulsant. The compound has formula (I); X2R1 when X2=S, HX2R1 when X2=S.

Abstract translation: 本发明涉及可用作抗惊厥药的化合物。 该化合物具有式（I）; X2R1当X2 = S时，HX2R1当X2 = S时。

公开(公告)号：WO1997033861A1

公开(公告)日：1997-09-18

申请号：PCT/US1997004579

申请日：1997-03-17

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  KOHN, Harold

IPC: C07C237/22

CPC classification number: C07C237/22 ,  A61K31/165 ,  C07B2200/07

Abstract: The present invention is directed to a compound in the R configuration about the asymmetric carbon in formula (I), wherein Ar is phenyl which is unsubstituted or substituted with at least one halo group; Q is lower alkoxy, and Q1 is methyl; pharmaceutical compositions containing same and the use thereof in treating CNS disorders in animals.

Abstract translation: 本发明涉及R构型中关于式（I）中不对称碳的化合物，其中Ar是未被取代或被至少一个卤素取代的苯基; Q是低级烷氧基，Q 1是甲基; 含有它们的药物组合物及其在治疗动物中的CNS紊乱中的用途。

公开(公告)号：EP0888289B1

公开(公告)日：2001-06-13

申请号：EP97916897.8

申请日：1997-03-17

Applicant: Research Corporation Technologies, Inc

Inventor： KOHN, Harold

IPC: C07C237/22 ,  A61K31/16

CPC classification number: C07C237/22 ,  A61K31/165 ,  C07B2200/07

Abstract: The present invention is directed to a compound in the R configuration about the asymmetric carbon in formula (I), wherein Ar is phenyl which is unsubstituted or substituted with at least one halo group; Q is lower alkoxy, and Q1 is methyl; pharmaceutical compositions containing same and the use thereof in treating CNS disorders in animals.

公开(公告)号：EP0888289A1

公开(公告)日：1999-01-07

申请号：EP97916897.0

申请日：1997-03-17

Applicant: Research Corporation Technologies, Inc

Inventor： KOHN, Harold

IPC: A61K31 ,  A61P25 ,  C07C237

CPC classification number: C07C237/22 ,  A61K31/165 ,  C07B2200/07

Abstract: The present invention is directed to a compound in the R configuration about the asymmetric carbon in formula (I), wherein Ar is phenyl which is unsubstituted or substituted with at least one halo group; Q is lower alkoxy, and Q1 is methyl; pharmaceutical compositions containing same and the use thereof in treating CNS disorders in animals.