公开(公告)号：WO1991008310A1

公开(公告)日：1991-06-13

申请号：PCT/US1990006887

申请日：1990-11-26

Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  PIENIAZEK, Norman, J. ,  SLEMENDA, Susan, B. ,  PIENIAZEK, Danuta ,  VELARDE, Jorge ,  LUFTIG, Ronald, B.

IPC: C12Q01/70

CPC classification number: C07K14/005 ,  A61K38/00 ,  C12N2710/10322

Abstract: The present invention relates to DNA and proteins of human Adenovirus Type 41 and their use in detection of said virus. More specifically, the present invention relates to the isolation of a 41.4 kd short fiber protein and a 60.6 kd long fiber protein of Adenovirus Type 41 (Ad41), as well as protein derived from the Ad41 E3 region, thereby providing virus-derived antigens and active derivatives and parts thereof, useful in the development of diagnostic assays, DNA probes and vaccines for said virus or other related viruses belonging to the human enteric family.

Abstract translation: 本发明涉及人腺病毒41型的DNA和蛋白质及其在检测所述病毒中的用途。 更具体地说，本发明涉及分离41.4kd的短纤维蛋白质和61.6型的Adenovirus 41型（Ad41）的长纤维蛋白质，以及衍生自Ad41 E3区域的蛋白质，从而提供病毒衍生的抗原和 活性衍生物及其部分，可用于开发用于所述病毒或属于人肠系氏病的其它相关病毒的诊断测定，DNA探针和疫苗。